Method and means for connecting and controlling a large number of contacts for electrical cell stimulation in living organisms

• US 8,565,868 B2
• Filed: 09/28/2009
• Issued: 10/22/2013
• Est. Priority Date: 09/29/2008
• Status: Active Grant

• Current Assignee: Chong I.L. Lee, Sergio Lara Pereira Monteiro
• Original Assignee: Chong I.L. Lee, Sergio Lara Pereira Monteiro
• Inventors: Lee, Chong Il, Monteiro, Sergio Lara Pereira
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): OROPEZA, FRANCES P
• Application Number:
  US12/586,763
• Publication Number:
  US 20100082076A1
• Time in Patent Office: 1,485 Days
• Field of Search: 607/2
• US Class Current: 607/2
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/6868 Brain
• CPC Class Codes: A61B 5/6869 Heart
• CPC Class Codes: A61B 5/6877 Nerve
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/3752 Details of casing-lead connections
• CPC Class Codes: G01R 1/06744 Microprobes, i.e. having dimensions as IC details
• CPC Class Codes: G01R 1/06766 Input circuits therefor
• CPC Class Codes: G01R 1/07307 with individual probe elements, e.g. needles, cantilever beams or bump contacts, fixed in relation to each other, e.g. bed of nails fixture or probe card

Abstract

A picafina, or lead, includes a decoder within the picafina to provide directional stimulation to a multitude of electrode pads. The system of address wires, control switches and demultiplexers selects one of a plurality of the electrode pads. Time delay switches control the fixed length of the time the cells receive the electrical stimulation. Alternatively the fixed length of the time the cells receive the electrical stimulation may be implemented by periodically disconnecting the stimulation voltage as the battery output.

Claims

1. A system for directionally stimulating a cell of a living organism, the system comprising:

a picafina with a proximal extremity, a distal extremity, an inner lumen and an outer shell enclosing the inner lumen;

a plurality of one or more electrodes;

an electrical energy storage means and an electronics controlling unit are electrically coupled with an address decoder which is located within the picafina, wherein the decoder is electrically coupled to the electrodes located on the picafina;

wherein the electronics controlling unit and the picafina are provided with digital electronics to identify the electrodes;

whereby the digital electronics select a subset of at least one of the plurality of one or more electrodes.

2. The system of claim 1, further comprising a first plurality of wires connecting the electronics controlling unit to the picafina, a digital address from the electronics controlling unit to the picafina.

3. The system of claim 2, further comprising a time delay circuit keeping the selected stimulating electrodes in a stimulating state for a fixed length of time after which the selected stimulating electrodes return to a non-stimulating state.

4. The system of claim 2, wherein the selected stimulation electrodes assume the stimulating state once the digital address in conveyed and the electrical energy storage means is activated, and the selected stimulating electrodes assume the non-stimulating state when de-activated by the electrical energy storage means.

5. The system of claim 1, wherein the picafina is implanted at a first location and the electrical energy storage means and electronics controlling unit are implanted at a second location.

6. The system of claim 1, wherein the electronics controlling unit acts under the command of an external operator via telemetry.

7. The system of claim 1, wherein the electronics controlling unit further includes a microcomputer which is configured to select the electrodes to become active.

8. A system for directionally stimulating a cell of a living organism, the system comprising:

a picafina with a proximal extremity, a distal extremity, an inner lumen and an outer shell enclosing the inner lumen;

a plurality of one or more electrodes;

an electrical energy storage means to provide a plurality of electrical energy levels;

the electrical energy storage means and an electronics controlling unit are electrically coupled with an address decoder which is located within the picafina, wherein the decoder is electrically coupled to the electrodes located on the picafina;

wherein the electronics controlling unit comprises digital electronics to identify the electrodes and a plurality of electrical energy levels;

whereby the digital electronics select a subset of at least one of the plurality of one or more electrodes and one of the plurality of electrical energy levels.

9. The system of claim 8, further comprising a first plurality of wires connecting the electronics controlling unit to the picafina, to convey a first digital address from the electronics controlling unit to the picafina to select the subset of electrodes and a second plurality of wires connecting the electronics controlling unit to the picafina to convey a second digital address from the electronics controlling unit to the picafina to select the energy level.

10. The system of claim 9, further comprising a time delay circuit keeping the selected stimulating electrodes in a stimulating state for a fixed length of time after which the selected stimulating electrodes return to a non-stimulating state.

11. The system of claim 9, wherein the selected stimulation electrodes assume the stimulating state once the digital address in conveyed and the electrical energy storage means is activated, and the selected stimulating electrodes assume the non-stimulating state when de-activated by the electrical energy storage means.

12. The system of claim 8, wherein the picafina is implanted at a first location and the electrical energy storage means and electronics controlling unit are implanted at a second location.

13. The system of claim 8, wherein the electronics controlling unit acts under the command of an external operator via telemetry.

14. The system of claim 8, wherein the electronics controlling unit further includes a microcomputer which is configured to select the electrodes to become active and the electrical energy level for electrical stimulation.