Ion storage device with direction-selective radial ejection

• US 8,581,185 B2
• Filed: 09/06/2011
• Issued: 11/12/2013
• Est. Priority Date: 06/21/2004
• Status: Active Grant

• Current Assignee: Thermo Finnigan LLC (Thermo Fisher Scientific Incorporated)
• Original Assignee: Thermo Finnigan LLC (Thermo Fisher Scientific Incorporated)
• Inventors: Makarov, Alexander A., Denisov, Eduard V., Kholomeev, Alexander
• Primary Examiner(s): Wells, Nikita
• Application Number:
  US13/226,390
• Publication Number:
  US 20110315873A1
• Time in Patent Office: 798 Days
• Field of Search: 250/292, 250/290, 250/293, 250/281, 250/283, 250/286, 363/171
• US Class Current: 250/292
• CPC Class Codes: H01J 49/0031 Step by step routines describing the use of the apparatus H01J49/0081 takes precedence
• CPC Class Codes: H01J 49/022 Circuit arrangements, e.g. for generating deviation currents or voltages regulating electric or magnetic variables in general, e.g. current, magnetic field G05F; Components associated with high voltage supply high voltage supply per se H02M
• CPC Class Codes: H01J 49/36 Radio frequency spectrometers, e.g. Bennett-type spectrometers, Redhead-type spectrometers
• CPC Class Codes: H01J 49/423 with radial ejection
• CPC Class Codes: H01J 49/427 Ejection and selection methods

Abstract

The present invention provides a radio frequency (RF) power supply in a mass spectrometer. The power supply provides an RF signal to electrodes of a storage device to create a trapping field. The RF field is usually collapsed prior to ion ejection. In an illustrative embodiment the RF power supply includes a RF signal supply; a coil arranged to receive the signal provided by the RF signal supply and to provide an output RF signal for supply to electrodes of an ion storage device; and a shunt including a switch operative to switch between a first open position and a second closed position in which the shunt shorts the coil output.

Claims

1. An ion storage device, comprising:

at least four elongated electrodes defining an ion storage volume, the electrodes defining first and second radial directions along with ions may be ejected from the ion storage volume to a location external to the ion storage device, the first and second radial directions being different;

a power supply for providing RF potentials to the at least four electrodes to establish an RF field that radially confines ions within the ion storage volume;

the power supply further providing independently controllable DC offsets to each one of the at least four electrodes, the power supply being configured to, in response to selection of one of the first or second radial directions, adjust DC offsets applied to the at least four electrodes to cause ions to be orthogonally ejected from the ion volume in the selected radial direction.

2. The ion storage device of claim 1, wherein the power supply includes:

an RF signal supply;

a coil having a primary winding coupled to the RF signal supply, and a plurality of secondary windings coupled to the at least four electrodes, the primary and plurality of secondary windings being arranged to induce RF signals in each of the plurality of secondary windings; and

a shunt including a switch, operative to switch between a first state in which the shunt shorts the coil to switch off the RF field in the ion trap, and a second state in which the RF field is established within the ion trap.

3. The ion storage device of claim 1, wherein each of the independently controllable DC offsets is delivered to a corresponding one of the secondary windings.

4. The ion storage device of claim 3, wherein each of the independently controlllable DC offsets is routed through a high voltage supply switch.

5. The ion storage device of claim 2 wherein the shunt switch is a semiconductor switch.

6. The ion storage device of claim 1, wherein the at least four electrodes each have a hyperbolic surface facing the ion storage volume.

7. The ion storage device of claim 1, wherein at least a first and a second electrode of the at least four electrodes are adapted with an aperture through which ions may travel.

8. The ion storage device of claim 7, wherein the power supply is selectively operable to apply a first set of DC offsets to the at least four electrodes to eject ions through the aperture in the first electrode or a second set of DC offsets to the at least four electrodes to eject ions through the aperture in the second electrode.

9. The ion storage device of claim 1, wherein a first adjacent pair of the at least four electrodes define a first gap therebetween and a second adjacent pair of the at least four electrodes define a second gap therebetween, and wherein the power supply is selectively operable to apply a first set of DC offsets to the at least four electrodes to eject ions through the first gap or a second set of DC offsets to the at least four electrodes to eject ions through the second gap.

10. A mass spectrometer, comprising:

an ion storage device including at least four elongated electrodes defining an ion storage volume;

a first mass analyzer positioned to receive ions orthogonally ejected from the ion storage device in a first radial direction;

a processing device including at least one of a collision/reaction cell and a second mass analyzer positioned to receive ions orthogonally ejected from the ion storage device in a second radial direction, the second radial direction being different from the first radial direction;

a power supply for providing RF potentials to the at least four electrodes to establish an RF field that radially confines ions within the ion storage volume;

the power supply further providing independently controllable DC offsets to each one of the at least four electrodes, the power supply being configured to, in response to selection of one of the first or second radial directions, adjust DC offsets applied to the at least four electrodes to cause ions to be orthogonally ejected from the ion volume in the selected radial direction.

11. The mass spectrometer of claim 10, wherein at least one of the first and second radial directions extends through an aperture formed in one of the electrodes.

12. The mass spectrometer of claim 10, wherein at least one of the first and second radial directions extends through a gap defined between adjacent electrodes.