Systems for deploying intraocular shunts

• US 8,585,629 B2
• Filed: 12/08/2011
• Issued: 11/19/2013
• Est. Priority Date: 11/15/2010
• Status: Active Grant

• Current Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Original Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Inventors: Grabner, Guenther, Reitsamer, Herbert A., Horvath, Christopher, Romoda, Laszlo O.
• Primary Examiner(s): MARCETICH, ADAM M
• Application Number:
  US13/314,946
• Publication Number:
  US 20120165721A1
• Time in Patent Office: 712 Days
• Field of Search: 604/8, 604/9, 604/10, 604/264, 604/43, 604/506, 604/60, 604/63, 604/73, 604/93.01, 604/117, 604/158, 604/59, 604/162, 604/164.01, 604/164.08, 604/164.09, 604/165.01, 606/167, 606/170, 606/172, 606/181, 606/184, 606/185, 606/190, 623/4.1, 623/5.11, 623/23.64
• US Class Current: 604/8
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

The present invention generally relates to systems for deploying intraocular shunts without the use of an optical apparatus that contacts an eye, such as a goniolens. In certain embodiments, systems of the invention include a locking mechanism, and a device configured to hold and deploy an intraocular shunt, in which a distal portion of the device is movable within a proximal portion of the device and the distal portion of the device is configured to mate with the locking mechanism to prevent movement of the distal portion when the locking mechanism is engaged.

Claims

1. A system for deploying an intraocular shunt, the system comprising:

a locking mechanism; and

a device configured to hold and deliver an intraocular shunt into an eye, the device comprising;

a housing comprising a proximal portion and a distal portion, the distal portion being movable within the proximal portion, the distal portion being configured to mate with the locking mechanism to prevent movement of the distal portion when the locking mechanism is engaged, the distal portion comprising a sleeve;

a deployment mechanism at least partially disposed within the housing; and

a hollow shaft coupled to the deployment mechanism, the shaft being configured to hold the intraocular shunt at least partially within the shaft; and

wherein the device has an insertion configuration in which the hollow shaft is fully disposed within the sleeve.

2. The system according to claim 1, wherein the locking mechanism is configured to fit at least partially around the distal portion of the device.

3. The system according to claim 1, wherein the locking mechanism comprises teeth that mate with holes in the distal portion of the device.

4. The system according to claim 1, further comprising an intraocular shunt that is at least partially disposed within the shaft.

5. The system according to claim 1, wherein a distal end of the distal portion forms an angle that is identical to an anterior chamber angle of an eye.

6. The system according to claim 1, wherein the deployment mechanism further comprises a member that limits axial retraction of the distal portion of the housing.

7. The system according to claim 1, wherein the distal portion comprises a capsule configured to mate with the locking mechanism.

8. The system according to claim 1, wherein the device comprises a shaft exposure configuration in which the shaft at least partially protrudes from the sleeve.

9. The system according to claim 8, wherein, when in the shaft exposure configuration, retraction of the distal portion into the proximal portion of the housing exposes a distal portion of the hollow shaft from the sleeve.

10. The system according to claim 1, wherein the deployment mechanism comprises a pusher component and a retraction component.

11. The system according to claim 1, wherein the hollow shaft is a needle.

12. The system according to claim 1, wherein the locking mechanism comprises a pair of arms.

13. A system for deploying an intraocular shunt, the system comprising:

a locking mechanism; and

a device configured to hold and deliver an intraocular shunt into an eye, the device comprising;

a housing comprising a proximal portion and a distal portion, the distal portion being movable within the proximal portion, the distal portion being configured to mate with the locking mechanism to prevent movement of the distal portion when the locking mechanism is engaged;

a deployment mechanism at least partially disposed within the housing, the deployment mechanism comprising a pusher component, a retraction component, and a rotatable component, wherein rotation of the rotatable component sequentially engages the pusher component and then the retraction component; and

a hollow shaft coupled to the deployment mechanism, the shaft being configured to hold the intraocular shunt at least partially within the shaft.

14. The system according to claim 13, further comprising an intraocular shunt that is at least partially disposed within the device.

15. The system according to claim 13, wherein the distal portion comprises a capsule configured to mate with the locking mechanism.

16. The system according to claim 13, wherein the pusher component is configured to push the shunt to partially deploy the shunt from within the shaft, and the retraction component is configured to retract the shaft from around the shunt.

17. The system according to claim 13, wherein the deployment mechanism further comprises at least one member that limits axial movement of the shaft.

18. The system according to claim 13, wherein the hollow shaft is a needle.

19. The system according to claim 13, wherein the device is a handheld device.

20. The system according to claim 13, wherein the device further comprises an indicator mechanism, formed on the housing and the deployment mechanism, that provides feedback to an operator as to the state of the deployment mechanism.

21. The system according to claim 20, wherein the indicator mechanism comprises a slot, formed in the housing and extending along the deployment mechanism, for providing visual indication of the state of the deployment mechanism.

22. A system for deploying an intraocular shunt, the system comprising:

a locking mechanism; and

a device configured to hold and deliver an intraocular shunt into an eye, the device comprising;

a housing comprising a proximal portion and a distal portion, the distal portion being movable within the proximal portion, the distal portion being configured to mate with the locking mechanism to prevent movement of the distal portion when the locking mechanism is engaged, the distal portion comprising a sleeve, a distal end of the sleeve comprising a protrusion;

a deployment mechanism at least partially disposed within the housing; and

a hollow shaft coupled to the deployment mechanism, the shaft being configured to hold the intraocular shunt at least partially within the shaft.

23. The system according to claim 22, wherein the device has an insertion configuration in which the hollow shaft is fully disposed within the sleeve.

24. The system according to claim 22, wherein the protrusion provides resistance against advancement of the device when the protrusion contacts scleral tissue on an inside of an anterior chamber.

25. The system according to claim 22, wherein the protrusion comprises a flat bottom portion and an angled top portion that is oriented at an angle with respect to the flat bottom portion.

26. The device according to claim 25, wherein the angle is an acute angle configured to be substantially identical to an anterior chamber angle of an eye.

27. The system according to claim 22, wherein the locking mechanism comprises a pair of arms.

28. The system according to claim 22, wherein the distal portion comprises a capsule configured to mate with the locking mechanism.