Method and apparatus for intra-aortic substance delivery to a branch vessel
First Claim
1. A method of delivering fluid into the right and left renal arteries of a patient in conjunction with a radiographic contrast material administration procedure, comprising:
- administering a radiographic contrast material to the patient;
placing a localized bifurcated drug delivery system within an abdominal aorta of the patient;
wherein the localized bifurcated drug delivery system comprises a first sub-catheter and a second sub-catheter extending distally from a bifurcation location;
maneuvering the first sub-catheter of the localized drug delivery system from the abdominal aorta into the right renal artery of the patient;
maneuvering the second sub-catheter of the localized drug delivery system from the abdominal aorta into the left renal artery of the patient;
delivering an amount of fluid through the localized drug delivery system;
passing a first portion of the amount of fluid through the first sub-catheter and into the right renal artery;
passing a second portion of the amount of fluid through the second sub-catheter and into the left renal artery; and
simultaneously performing an interventional procedure on the patient such that the interventional procedure and the localized drug delivery are performed through a single percutaneous access.
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Accused Products
Abstract
A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.
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Citations
19 Claims
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1. A method of delivering fluid into the right and left renal arteries of a patient in conjunction with a radiographic contrast material administration procedure, comprising:
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administering a radiographic contrast material to the patient; placing a localized bifurcated drug delivery system within an abdominal aorta of the patient;
wherein the localized bifurcated drug delivery system comprises a first sub-catheter and a second sub-catheter extending distally from a bifurcation location;maneuvering the first sub-catheter of the localized drug delivery system from the abdominal aorta into the right renal artery of the patient; maneuvering the second sub-catheter of the localized drug delivery system from the abdominal aorta into the left renal artery of the patient; delivering an amount of fluid through the localized drug delivery system; passing a first portion of the amount of fluid through the first sub-catheter and into the right renal artery; passing a second portion of the amount of fluid through the second sub-catheter and into the left renal artery; and simultaneously performing an interventional procedure on the patient such that the interventional procedure and the localized drug delivery are performed through a single percutaneous access. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of delivering fluid into the right and left renal arteries of a patient in conjunction with a cardiac procedure, comprising:
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performing the cardiac procedure on the patient; placing a localized drug delivery system within an abdominal aorta of the patient; maneuvering a first sub-catheter of the localized drug delivery system from the abdominal aorta into the right renal artery of the patient; maneuvering a second sub-catheter of the localized drug delivery system from the abdominal aorta into the left renal artery of the patient;
wherein the first sub-catheter and the second-sub catheter extend bilaterally from a bifurcation location at a distal end of the localized drug delivery system;delivering an amount of fluid through the localized drug delivery system; wherein the cardiac procedure is performed simultaneously on the patient through a single percutaneous access. - View Dependent Claims (15)
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16. A method of delivering fluid into the right and left renal arteries of a patient comprising:
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placing a localized drug delivery system within an abdominal aorta of the patient, the localized drug delivery system comprising a bifurcated catheter having a first sub-catheter in fluid communication with a second sub-catheter; maneuvering a first sub-catheter of the localized drug delivery system from the abdominal aorta through a right renal ostia, and into the right renal artery of the patient; maneuvering a second sub-catheter of the localized drug delivery system from the abdominal aorta through a left renal ostia, and into the left renal artery of the patient; delivering an amount of fluid through the localized drug delivery system while allowing an amount of blood to flow through the abdominal aorta of the patient from a location upstream of the right and left ostia along the abdominal aorta to a location downstream of the right and left ostia; passing a first portion of the amount of fluid through the first sub-catheter and into the right renal artery; and passing a second portion of the amount of fluid through the second sub-catheter and into the left renal artery; and simultaneously performing cardiac procedure on the patient. - View Dependent Claims (17, 18, 19)
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Specification