Methods of treating valves

• US 8,585,756 B2
• Filed: 10/24/2011
• Issued: 11/19/2013
• Est. Priority Date: 08/03/2001
• Status: Expired due to Term

• Current Assignee: JenaValve Technology, Inc., Medtronic Vascular Galway Limited (Medtronic Plc)
• Original Assignee: JenaValve Technology, Inc., Medtronic Vascular Galway Limited (Medtronic Plc)
• Inventors: Bonhoeffer, Philipp, Boudjemline, Younes
• Primary Examiner(s): SEVERSON, RYAN J
• Application Number:
  US13/279,800
• Publication Number:
  US 20120209374A1
• Time in Patent Office: 757 Days
• Field of Search: 606/108, 606/200, 623/1.11, 623/1.12, 623/1.23, 623/1.24, 623/1.26, 623/1.36, 623/2.11, 623/23.68
• US Class Current: 623/2.11
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/001 for adjusting a diameter

Abstract

The implant implantation unit (2), at a determined position in the tubular element (51) with a wall comprising a cavity (50), is pushed there by a catheter (60) and the unit comprises deformable feelers (31) to, under the control of remote activation elements (42), change from a stowed form to a deployed functional form, to detect the cavity (50) and position itself there with reference to the position of the cavity.

Claims

1. A method of treating a native valve, the method comprising:

delivering an expandable anchor and a valve prosthesis to a vicinity of the native valve, wherein feeler elements extend from the anchor;

positioning the anchor and the feeler elements so that the native valve leaflets are between the feeler elements and the anchor;

expanding the anchor from a collapsed delivery configuration to an expanded configuration; and

positioning a proximal end of the anchor further from a left ventricle than a distal end of the anchor,

wherein the valve prosthesis allows the flow of blood through the valve prosthesis in a first configuration and prevents the flow of blood through the valve prosthesis in a second configuration.

2. The method of claim 1, wherein positioning the anchor and feeler elements comprise positioning the feeler elements radially outward of the native valve leaflets and positioning the anchor radially inward of the native valve leaflets.

3. The method of claim 1, wherein expanding the anchor from a collapsed delivery configuration to an expanded configuration comprises allowing the anchor to self-expand.

4. The method of claim 1, wherein the expandable anchor and the valve prosthesis are delivered separately.

5. The method of claim 1, wherein delivering the expandable anchor and valve prosthesis comprises endovascularly delivering the expandable anchor and valve prosthesis.

6. The method of claim 1, wherein the native valve is a native aortic valve.

7. A method of treating a native valve insufficiency, comprising:

positioning at least one feeler element in a cavity defined at least partially by a valve leaflet and a surface to which the valve leaflet is attached; and

positioning a carrier element configured to support a valve prosthesis on a side of the valve leaflet opposite to the cavity.

8. The method of claim 7, further comprising exerting an outward radial force via the

carrier element on the valve leaflet.

9. The method of claim 8, wherein exerting the radial force comprises exerting a radial force sufficient to anchor the carrier element in position relative to the valve leaflet.

10. The method of claim 8, wherein exerting the radial force via the carrier element comprises exerting a radial force via a shape memory alloy mesh.

11. The method of claim 7, wherein positioning the carrier element comprises positioning a carrier element supporting a valve prosthesis.

12. The method of claim 7, wherein positioning the carrier element comprises positioning the carrier element in a space substantially surrounded by a plurality of valve leaflets.

13. The method of claim 12, wherein positioning the at least one feeler element comprises respectively positioning a plurality of feeler elements connected to the carrier element in respective cavities defined by the plurality of valve leaflets and a surface to which the plurality of leaflets are attached.

14. The method of claim 12, wherein positioning the at least one feeler element comprises respectively positioning a plurality of feeler elements connected to the carrier element in locations disposed radially outward relative to the space.

15. The method of claim 7, wherein positioning the at least one feeler element comprises positioning a plurality of feeler elements into respective cavities defined by each of a respective plurality of valve leaflets and a wall to which the valve leaflets are attached.

16. The method of claim 15, wherein positioning the plurality of feeler elements comprises positioning exactly three feeler elements.

17. The method of claim 7, wherein positioning the at least one feeler element comprises positioning the at least one feeler element in a cavity defined by an aortic valve leaflet and a wall of the aorta to which the aortic valve leaflet is attached.

18. The method of claim 7, wherein positioning the at least one feeler element comprises positioning the at least one feeler element in a cavity defined by the valve leaflet and a wall of a blood vessel to which the valve leaflet is attached.

19. The method of claim 7, wherein the native valve is an aortic valve.

20. The method of claim 7, wherein the native valve is a native heart valve.

21. The method of claim 7, wherein positioning the carrier element comprises positioning a carrier element comprising a tubular mesh.

22. The method of claim 7, wherein positioning the at least one feeler element in the cavity comprises positioning a rounded end of the at least one feeler element in the cavity.

23. The method of claim 7, wherein positioning the carrier element comprises positioning a self-expandable carrier element.

24. The method of claim 7, wherein positioning the at least one feeler element comprises positioning at least one feeler element that is connected to and extends radially outward from the carrier element.

25. The method of claim 24, wherein positioning the at least one feeler element further comprises positioning at least one feeler element that extends radially outward at an acute angle relative to a longitudinal axis of the carrier element.

26. The method of claim 7, wherein positioning the at least one feeler element comprises positioning at least one feeler element that is connected and expandable radially outwardly relative to the carrier element.

27. A method of treating a valve insufficiency, comprising:

positioning at least one feeler element radially outward relative to a valve leaflet; and

positioning a carrier element configured to support a valve prosthesis radially inward relative to the valve leaflet.

28. The method of claim 27, further comprising exerting an outward radial force via the carrier element on the valve leaflet.

29. The method of claim 27, wherein positioning the carrier element comprises positioning a carrier element supporting a valve prosthesis.

30. The method of claim 27, wherein positioning the carrier element comprises positioning the carrier element radially inward relative to a plurality of valve leaflets, and wherein positioning the at least one feeler element comprises positioning a plurality of feeler elements radially outward relative to the plurality of valve leaflets, respectively.

31. The method of claim 27, wherein the valve is a native heart valve.

32. The method of claim 27, wherein positioning the carrier element comprises positioning a carrier element comprising a tubular mesh.

33. The method of claim 27, wherein positioning the at least one feeler element comprises positioning at least one feeler element that is connected and expandable radially outwardly relative to the carrier element.

34. A method of treating a native heart valve insufficiency by placement of a valve prosthesis, the method comprising:

positioning three feeler elements in respective cavities defined between respective native heart valve leaflets and a blood vessel wall to which the respective native heart valve leaflets are attached;

positioning in a space surrounded by the native heart valve leaflets a tubular carrier element to which the three feeler elements are connected, wherein the carrier element has a collapsed configuration and expanded configuration and supports a valve prosthesis; and

exerting an outward radial force against the native valve leaflets via the carrier element in the expanded configuration to anchor the valve prosthesis in place relative to the native heart valve.

35. The method of claim 34, wherein positioning the three feeler elements comprises positioning three feeler elements that are connected and expandable radially outwardly relative to the carrier element.