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HLA homozygous cells

  • US 8,586,358 B2
  • Filed: 12/21/2011
  • Issued: 11/19/2013
  • Est. Priority Date: 03/09/2007
  • Status: Active Grant
First Claim
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1. An isolated human stem cell or a progeny thereof, wherein the stem cell or progeny thereof is homozygous for a human leukocyte antigen (HLA) haplotype, the HLA haplotype comprising an entire HLA locus;

  • and wherein at least about 90% of the non-HLA loci in the cell or progeny thereof are heterozygous and the cell is not a parthenogenic stem cell.

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