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Method and apparatus for nanoparticle electrogenerated chemiluminescence amplification

DC CAFC
  • US 8,586,378 B2
  • Filed: 04/07/2009
  • Issued: 11/19/2013
  • Est. Priority Date: 04/11/2008
  • Status: Active Grant
First Claim
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1. A method of analyzing a sample comprising:

  • contacting a liquid sample with a working electrode;

    wherein the liquid sample comprises a plurality or electrogenerated chemiluminescent (ECL) moieties and a colloidal suspension of one or more conductive or redox active nanoparticles; and

    detecting one or more transient optical properties resulting from interaction of the one or more nanoparticles and the sample at the working electrode;

    wherein the one or more transient optical properties comprise an ECL intensity vs. time transient resulting from redox reactions of the ECL moieties, with or without coreactants, catalyzed by an individual nanoparticle.

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