System and method for radioactive emission measurement
First Claim
1. A method of radioactive-emission-measurement, comprising:
- providing a SPECT camera for the detection of single emissions, which camera having a region of interest having a volume of at least 5×
5×
5 cm and a side closer to said region of interest;
arranging said camera so that said region of interest coincides with a human body;
imaging the region of interest from different orientations, using at least three detecting blocks each arranged to view said region of interest at a different orientation from others of said blocks, wherein said imaging comprises detecting at least 1 of every 5000 photons emitted from at least one radioactive-emission source located within said region-of-interest volume, through a collimator positioned in front of at least one pixel of each of the detecting blocks thereby blocking gamma and beta radiation and defining a viewing angle of at least 0.005 steradians; and
reconstructing a SPECT volumetric radioactive-emission image from said detected photons at a resolution of 7 mm Full Width Half Maximum (FWHM) or better, said resolution defined under conditions of irradiation by a substantially line source of radioactive emission, with an activity of 5 mCi, within said region-of-interest volume, at a distance of at least 100 mm from said side.
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Abstract
A method of radioactive-emission-measurement. The method comprises providing a camera for the detection of single emissions, which defines proximal and distal ends. The camera is configured for enabling a reconstruction of a volumetric image having a line spread function of less than 7 mm Full Width Half Maximum (FWHM) when given a substantially line source of radioactive emission, with an activity of 5 mCi, within a region-of-interest volume, at a distance of at least 100 mm from said distal end, with air being substantially the only operating medium. The method further comprises detecting at least 1 of every 5000 photons, emitted from at least one radioactive-emission source, located within a certain region-of-interest volume, using the camera, and reconstructing a volumetric radioactive-emission image from the detected photons.
725 Citations
65 Claims
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1. A method of radioactive-emission-measurement, comprising:
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providing a SPECT camera for the detection of single emissions, which camera having a region of interest having a volume of at least 5×
5×
5 cm and a side closer to said region of interest;arranging said camera so that said region of interest coincides with a human body; imaging the region of interest from different orientations, using at least three detecting blocks each arranged to view said region of interest at a different orientation from others of said blocks, wherein said imaging comprises detecting at least 1 of every 5000 photons emitted from at least one radioactive-emission source located within said region-of-interest volume, through a collimator positioned in front of at least one pixel of each of the detecting blocks thereby blocking gamma and beta radiation and defining a viewing angle of at least 0.005 steradians; and reconstructing a SPECT volumetric radioactive-emission image from said detected photons at a resolution of 7 mm Full Width Half Maximum (FWHM) or better, said resolution defined under conditions of irradiation by a substantially line source of radioactive emission, with an activity of 5 mCi, within said region-of-interest volume, at a distance of at least 100 mm from said side. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64)
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65. A radioactive-emission-measurement system, comprising:
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a camera for the detection of single emissions having at least three detecting blocks, the camera having a geometry such that said at least three detecting blocks detects at least 1 of every 5000 photons, emitted from at least one radioactive-emission source, located within a region-of-interest volume of at least 5×
5×
5 cm, wherein each said detecting block comprising one or more collimated solid-state ionizing radiation detecting units, each detecting unit including at least one pixel, each said detecting block has at least one collimator positioned in front of said at least one pixel, said at least one collimator substantially blocks gamma and beta radiation and defines a viewing angle of at least 0.005 steradians, said detecting blocks having different lines of sight and arranged to view said region of interest at a different orientation from others of said blocks; anda data-processing system, configured for reconstructing a radioactive-emission SPECT image from detected photons under a Cobalt wire Nema test, said radioactive-emission SPECT image having a voxel size of 7 mm or less.
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Specification