Implantable wireless accoustic stimulators with high energy conversion efficiencies

• US 8,588,926 B2
• Filed: 01/04/2013
• Issued: 11/19/2013
• Est. Priority Date: 03/25/2008
• Status: Active Grant

• Current Assignee: EBR Systems, Inc.
• Original Assignee: EBR Systems, Inc.
• Inventors: Moore, David F., Mohr, Paul, Willis, N. Parker, Brisken, Axel F.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US13/734,680
• Publication Number:
  US 20130197609A1
• Time in Patent Office: 319 Days
• Field of Search: 607/33
• US Class Current: 607/61
• CPC Class Codes: A61B 2560/0214 of power generation or supply
• CPC Class Codes: A61N 1/02 Details
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/362 Heart stimulators heart defibrillators A61N1/39
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3758 Packaging of the components within the casing
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: H02N 2/181 Circuits; Control arrangements or methods
• CPC Class Codes: H02N 2/186 Vibration harvesters
• CPC Class Codes: H02N 2/188 adapted for resonant operation
• CPC Class Codes: H10N 30/03 Assembling devices that include piezoelectric or electrostrictive parts
• CPC Class Codes: H10N 30/30 with mechanical input and electrical output, e.g. functioning as generators or sensors
• CPC Class Codes: Y10T 29/42 Piezoelectric device making

Abstract

Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

Claims

1. An implantable receiver-stimulator for harvesting acoustic power from an acoustic field and generating electrical power, comprising:

a hermetically sealed enclosure with an inner and outer surface;

a first plurality of acoustic piezoelectric components which converts the acoustic field to electrical power, each piezoelectric component defined by a thickness and a base with a width and configured with the base mounted to the inner surface;

a plurality of individual rectifiers, where each rectifier is electrically connected to a corresponding piezoelectric component of the first plurality of piezoelectric components such that the electrical power from the piezoelectric components is converted by the rectifiers arranged in a circuit assembly to a biologically stimulating electrical output; and

at least two stimulation electrodes which receive the stimulating electrical output and deliver said output to tissue at sufficient electrical energy levels to stimulate the tissue;

wherein the acoustic piezoelectric components are distributed about the inner surface along three axes such that acoustic energy is harvested efficiently from any direction of the propagating acoustic energy field.

2. The device of claim 1, wherein at least part of the inner surface is configured as a circuit, optionally wherein the acoustic piezoelectric components and the rectifier circuitry are disposed on the circuit.

3. The device of claim 2, wherein the acoustic piezoelectric components are composed of a piezoelectric material, optionally wherein the piezoelectric material is one of a polycrystalline ceramic piezoelectric material or a single crystal piezoelectric material.

4. The device of claim 1, wherein the rectifier circuit assembly configures the rectifiers in parallel and comprises protection circuitry to protect the rectifiers front damage due to high voltages for example above approximately 4V.

5. The device of claim 4, wherein the protection, circuitry comprises a Zener diode or a series of GaAs Schottky diodes.

6. The device of claim 1, wherein the rectifier circuit assembly comprises one or more rectifiers connected to the stimulation electrodes and circuitry to remove residual charge accumulated on the stimulation electrodes.

7. The device of claim 1, wherein the hermetically sealed enclosure further comprises an end cap having a second plurality of acoustic piezoelectric components composed of a piezoelectric material, wherein the second plurality of acoustic piezoelectric components has a piezoelectric axis that is substantially perpendicular to that of the first plurality of piezoelectric components.

8. The device of claim 1, further comprising:

circuitry to limit said stimulating electrical output, thereby preventing harmful effects to the patient.

9. The device of claim 1, wherein the inner or outer surface of the hermetically sealed enclosure is etched to form a plurality of apertures each defined by a width and length;

and the acoustic piezoelectric components are each affixed to the inner surface at a location of the etched acoustic aperture, wherein one or more of the etched acoustic apertures is larger than the widths and/or lengths of the piezoelectric components affixed to the aperture location.

10. An implantable receiver-stimulator for harvesting acoustic power from an acoustic field and generating electrical power, comprising:

a hermetically sealed enclosure with an inner and outer surface;

a first plurality of acoustic piezoelectric components which converts the acoustic field to electrical power, each piezoelectric component defined by a thickness and a base with a width and configured with the base mounted to the inner surface;

a plurality of individual rectifiers, where each rectifier is electrically connected to a corresponding piezoelectric component of the first plurality of piezoelectric components such that the electrical power from the piezoelectric components is converted by the rectifiers arranged in a circuit assembly to a biologically stimulating electrical output; and

at least two stimulation electrodes which receive the stimulating electrical output and deliver said output to tissue at sufficient electrical energy levels to stimulate the tissue;

wherein the acoustic piezoelectric components are distributed about the inner surface longitudinally and perimetrically such that acoustic energy is harvested efficiently from any direction of the propagating acoustic energy field.