Piezoelectric stimulation device

• US 8,588,930 B2
• Filed: 03/26/2010
• Issued: 11/19/2013
• Est. Priority Date: 06/07/2005
• Status: Active Grant

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: DiUbaldi, Anthony, Wahlgren, Stephen, Tracey, Michael R.
• Primary Examiner(s): BEHRINGER, LUTHER G
• Application Number:
  US12/661,949
• Publication Number:
  US 20100249677A1
• Time in Patent Office: 1,334 Days
• Field of Search: 607/41, 607/71
• US Class Current: 607/71
• CPC Class Codes: A61B 2562/028 Microscale sensors, e.g. electromechanical sensors [MEMS]
• CPC Class Codes: A61B 5/6874 Bladder
• CPC Class Codes: A61H 2201/5005 for controlling frequency distribution, modulation or interference of a driving signal
• CPC Class Codes: A61H 23/0245 with ultrasonic transducers, e.g. piezoelectric
• CPC Class Codes: A61N 1/32 alternating or intermittent currents applying electric fields by inductive or capacitive coupling A61N1/40; microwave apparatus A61N5/02
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.

Claims

1. A stimulation device comprising:

an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal;

wherein the external non-implantable transmitting device produces high frequency burst packets and comprises;

a first waveform generator for generating a first waveform having a frequency adapted to stimulate a predetermined body part, wherein the generated first waveform is itself incapable of transdermally stimulating the predetermined body part;

a second waveform generator for generating a carrier waveform having a frequency greater than that of the first waveform and adapted to puss through skin and tissue to the predetermined body part, the frequency of the generated carrier waveform is capable of reaching the predetermined body part but is itself incapable of electrically stimulating the predetermined body part;

an amplitude modulation device electrically coupled to the first and second waveform generators and configured to multiply the carrier waveform and the first waveform and producing a modulated waveform adapted to transdermally electrically stimulate the predetermined body part, the modulated waveform maintains the amplitude and frequency information of the first waveform and carrier waveform;

a surface electrode electrically coupled to the modulation device applying the modulated waveform transcutaneously;

a surface electrode applying the generated electrical waveform signal transcutaneously; and

an implantable piezoelectric element receiving the applied electrical waveform signal generated transcutaneously and causing mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part.

2. The stimulation device in accordance with claim 1, wherein the predetermined body part is a nerve and the mechanical vibration of the implantable piezoelectric element is sufficient to fire an action potential.

3. The stimulation device in accordance with claim 1, wherein the piezoelectric element is in direct contact with the predetermined body part.

4. The stimulation device in accordance with claim 1, wherein the piezoelectric element is in indirect contact with the predetermined body part via a biological volume conducting medium including at least one of muscle, fat or extracellular fluid.

5. The stimulation device in accordance with claim 2, wherein the external non-implantable transmitting device produces a high frequency continuous waveform and the stimulation device further comprises a dampening mechanism including one of a spring, cantilever or fluid encompassing the piezoelectric element for downshifting, a resonant frequency of the piezoelectric element.

6. The stimulation device in accordance with claim 5, wherein the high frequency continuous waveform is within the range of approximately 100 kHz-approximately 1 MHz, and the resonant frequency of the piezoelectric element is downshifted to within the range of approximately 1 Hz-approximately 40 Hz.

7. The stimulation device in accordance with claim 1, wherein the modulated waveform matches a resonant frequency of the piezoelectric element to produce mechanical vibration sufficient to stimulate the predetermined body part.

8. The stimulation device in accordance with claim 7, wherein the frequency of the first waveform is within the range of approximately 1 Hz-approximately 40 Hz.

9. The stimulation device in accordance with claim 8, wherein the frequency of the carrier waveform is within the range of approximately 100 kHz-approximately 1 MHz.

10. The stimulation device in accordance with claim 1, wherein the implantable piezoelectric element is disposed within a collapsible cage.

11. A method for stimulating the predetermined body part using the stimulation device in accordance with claim 1, the method comprising the steps of:

implanting the piezoelectric element proximate the predetermined body part;

generating the electrical waveform signal using, the external non-implantable transmitting device powered by the power source;

applying the generated electrical waveform signal transcutaneously through skin via the surface electrode;

receiving the applied electrical waveform signal generated transcutaneously at the piezoelectric element implanted proximate the predetermined body part and causing mechanical deformation resulting in mechanical vibration of the piezoelectric element sufficient to stimulate the predetermined body part.

12. The method in accordance with claim 11, wherein the predetermined body part is a nerve and the mechanical vibration of the implantable piezoelectric element is sufficient to lire an action potential.

13. The method in accordance with claim 11, wherein the piezoelectric element is in direct contact with the predetermined body part.

14. The method in accordance with claim 11, wherein the piezoelectric element is disposed in a biologically volume conducting medium sufficient to impart mechanical vibrations indirectly to the predetermined body part, wherein the biological volume conducting medium is at least one of muscle, fat or extracellular fluid.

15. The method in accordance with claim 11, wherein the external non-implantable transmitting device produces a high frequency continuous waveform;

and prior to being received by the piezoelectric element, further comprising the step of downshifting a resonant frequency of the piezoelectric element to a predetermined frequency for stimulating the predetermined body part.

16. The method in accordance with claim 15, wherein the high frequency continuous waveform is within the range of approximately 100 kHz-approximately 1 MHz, and the resonant frequency of the piezoelectric element is downshifted to within the range of approximately 1 Hz-approximately 40 Hz.

17. The method in accordance with claim 16, wherein the downshifting of the resonant frequency of the applied electric waveform signal is achieved using one of a spring, cantilever or fluid encompassing the piezoelectric element.

18. The method in accordance with claim 11, wherein the external non-implantable transmitting device produces high frequency burst packets produced by the following steps:

generating using the first waveform generator said first waveform having said frequency adapted to stimulate the predetermined body part, wherein the generated first waveform is itself incapable of transdermally electrically stimulating the predetermined body part;

generating using the second waveform generator said carrier waveform having said frequency greater than that of the first waveform and adapted to pass through skin and tissue to the predetermined body part, the generated carrier waveform is capable of reaching the predetermined body part but is itself incapable of electrically stimulating the predetermined body part;

modulating using the amplitude modulation device electrically coupled to the first and second waveform generators for multiplying the carrier waveform by the first waveform and producing a modulated waveform adapted to transdermally electrically stimulate the redetermined body part, the surface electrode being electrically coupled to the modulation device to apply the modulated waveform transcutaneously.

19. The method in accordance with claim 18, wherein the modulated waveform matches a resonant frequency of the piezoelectric element to produce mechanical vibration sufficient to stimulate the predetermined body part.

20. The method in accordance with claim 18, wherein the frequency of the first waveform is within the range of approximately 1 Hz-approximately 40 Hz.

21. The method in accordance with claim 20, wherein the frequency of the carrier waveform is within the range of approximately 100 kHz-approximately 1 MHz.