Neurostimulation system and method for measuring patient activity

• US 8,594,785 B2
• Filed: 02/01/2008
• Issued: 11/26/2013
• Est. Priority Date: 02/01/2007
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Bradley, Kerry A.
• Primary Examiner(s): PATTON, AMANDA K
• Application Number:
  US12/024,947
• Publication Number:
  US 20080188909A1
• Time in Patent Office: 2,125 Days
• Field of Search: 607/8, 607 17- 18, 607 28- 29
• US Class Current: 607/8
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61N 1/36071 Pain

Abstract

Electrical energy is conveyed via an implanted tissue stimulation system into tissue of the patient over a period of time. Electrical parameter data (e.g., impedance data and/or field potential data) is measured based on the electrical energy conveyed into the tissue of the patient, whereby the electrical parameter data is modulated in response to the physical activity of the patient to generate a time-varying signal (e.g., an oscillating signal). The time-varying signal is analyzed, and the physical activity of the patient (e.g., the physical activity level of the patient or the physical events performed by the patient) is tracking during the time period based on the analyzed time-varying signal.

Claims

1. A method of providing therapy to a patient, comprising:

conveying time-varying electrical energy having an envelope from an implanted tissue stimulation device into tissue of the patient over a period of time, whereby the envelope of the electrical energy is modulated in response to physical activity of the patient;

deriving a time-varying signal containing electrical parameter data from the modulated time-varying electrical energy;

analyzing the time-varying signal; and

tracking the physical activity of the patient during the time period based on the analyzed time-varying signal, wherein the tracked physical activity is indicative of the efficacy of the therapy provided to the patient.

2. The method of claim 1, wherein the electrical energy conveyed from the tissue stimulation device provides therapy to the patient.

3. The method of claim 1, wherein the electrical parameter data is one or both of electrical impedance data or field potential data.

4. The method of claim 1, wherein the time-varying signal analysis comprises determining a magnitude of the time-varying signal.

5. The method of claim 4, wherein the time-varying signal magnitude determination comprises detecting peak-to-peak amplitude values of the time-varying signal, detecting an energy of the time-varying signal, or detecting an envelope of the time-varying signal.

6. The method of claim 1, wherein the time-varying signal analysis comprises determining a morphology of the time-varying signal.

7. The method of claim 6, wherein the time-varying signal morphology determination comprises detecting an envelope of the time-varying signal.

8. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the physical activity level of the patient.

9. The method of claim 8, wherein determining the physical activity level of the patient comprises determining whether the physical activity level is relatively high or the physical activity level is relatively low.

10. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the different types of physical events performed by the patient.

11. The method of claim 10, wherein the different types of physical events performed by the patient comprise at least two of laying down, walking, jogging, jumping, sitting, and twisting.

12. The method of claim 10, wherein the different types of physical events are stored in a look-up table respectively correlated to previously measured reference electrical parameter data, wherein tracking the different types of physical events performed by the patient comprises comparing the measuring electrical parameter data to the reference electrical parameter data stored in the look-up table, and determining the different types of physical activity during the time period based on the comparison.

13. The method of claim 1, further comprising modifying therapy provided to the patient by the stimulation device based on the tracked physical activity.

14. The method of claim 1, wherein the time-varying signal is an oscillating signal.

15. The method of claim 1, further comprising determining whether the conveyed electrical energy is effective based on the tracked physical activity of the patient.

16. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the time that physical activity is performed by the patient.

17. The method of claim 16, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is performed by the patient during a first time period of a 24-hour day or performed by the patient during a second time period of the 24-hour day.

18. The method of claim 17, wherein the first time period is a daytime and the second time period is a nighttime.

19. The method of claim 16, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is Circadian in nature.

20. The method of claim 1, wherein the patient activity is indicative of whether the therapy provided to the patient treats pain.

21. The method of claim 1, wherein the patient activity is one or both of a footfall and a postural change.

22. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking a time at which physical activity is performed by the patient.

23. A tissue stimulation system, comprising:

an implantable electrode lead;

an implantable electrical stimulation device configured for being coupled to the electrode lead, the electrical stimulation device configured for conveying time-varying electrical energy from the electrode lead into tissue of a patient over a period of time, the time-varying electrical energy having an envelope capable of being modulated in response to physical activity of the patient, the electrical stimulation device further configured for deriving a time-varying signal containing electrical parameter data from the electrical energy conveyed into the tissue of the patient; and

a processing device configured for analyzing the time-varying signal, and tracking the physical activity of the patient during the time period based on the analyzed time-varying signal, wherein the tracked physical activity is indicative of the efficacy of the therapy provided to the patient.

24. The system of claim 23, wherein the stimulation device is configured for conveying the electrical energy from the implanted from the electrode lead to provide therapy to the patient.

25. The system of claim 23, wherein the electrical parameter data is one or both of electrical impedance data or field potential data.

26. The system of claim 23, wherein the processing device is the stimulation device.

27. The system of claim 23, wherein the processing device is an external programmer configured for communicating with the stimulation device.

28. The system of claim 23, wherein the time-varying signal analysis comprises determining a magnitude of the time-varying signal.

29. The system of claim 28, wherein the time-varying signal magnitude determination comprises detecting peak-to-peak amplitude values of the time-varying signal, detecting an energy of the time-varying signal, or detecting an envelope of the time-varying signal.

30. The system of claim 23, wherein the time-varying signal analysis comprises determining a morphology of the time-varying signal.

31. The system of claim 30, wherein the time-varying signal morphology determination comprises detecting an envelope of the time-varying signal.

32. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the physical activity level of the patient.

33. The system of claim 32, wherein determining the physical activity level of the patient comprises determining whether the physical activity level is relatively high or the physical activity level is relatively low.

34. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the physical events performed by the patient.

35. The system of claim 34, wherein the different types of physical events performed by the patient comprise at least two of laying down, walking, jogging, jumping, sitting, and twisting.

36. The system of claim 34, further comprising a look-up table storing the different types of physical events respectively correlated to previously measured reference electrical parameter data, wherein tracking the different types of physical events performed by the patient comprises comparing the measuring electrical parameter data to the reference electrical parameter data stored in the look-up table, and determining the different types of physical activity during the time period based on the comparison.

37. The system of claim 23, wherein the time-varying signal is an oscillating signal.

38. The system of claim 23, wherein the processing device is further configured for determining whether the conveyed electrical energy is effective based on the tracked physical activity of the patient.

39. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the time that physical activity is performed by the patient.

40. The system of claim 39, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is performed by the patient during a first time period of a 24-hour day or performed by the patient during a second time period of the 24-hour day.

41. The system of claim 40, wherein the first time period is a daytime and the second time period is a nighttime.

42. The system of claim 39, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is Circadian in nature.

43. The system of claim 23, wherein the patient activity is indicative of whether the therapy provided to the patient treats pain.

44. The system of claim 23, wherein the patient activity is one or both of a footfall and a postural change.

45. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking a time at which physical activity is performed by the patient.