Responsive electrical stimulation for movement disorders
First Claim
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1. A system for treating a movement disorder in a human patient comprising:
- at least one sensor configured for being in operable communication with an implantable responsive neurostimulator configured to deliver a form of electrical stimulation in response to events detected in physiological signals sensed by sensors, the implantable responsive neurostimulator provided with;
a sensor interface configured to receive and continuously monitor at least one physiological signal sensed by the at least one sensor, the at least one physiological signal corresponding to electrical activity of the brain;
a signal processor configured for processing the at least one signal to digitize the at least one signal;
a detection subsystem configured for analyzing the at least one signal to determine whether a tremor characteristic of an episode of the movement disorder experienced by the human patient is occurring by;
measuring an amplitude of the at least one signal;
calculating an average amplitude of the at least one signal over a predetermined period of time;
comparing the average amplitude to a dynamic threshold that is a fixed offset of a long-term moving average amplitude wherein the long-term moving average amplitude is calculated from data in which no tremors occur; and
detecting a tremor event if the calculated average amplitude exceeds the dynamic threshold;
a stimulation subsystem configured for generating and then controllably delivering through at least one stimulation electrode the form of electrical stimulation to the patient for so long as the tremor event is detected and to cease delivery of the treatment when the tremor event is no longer detected, wherein measuring, calculating, detecting, and generating and delivering of the electrical stimulation occurs without requiring a previous neurostimulation to have been applied;
a memory adapted to store data corresponding to detection by the detection subsystem of a tremor event and data corresponding to the form of electrical stimulation delivered by the stimulation subsystem; and
a central processor in operable communication either directly or indirectly with the sensor interface, the signal processor, the detection subsystem, the stimulation subsystem, and the memory.
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Abstract
An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of supplying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.
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Citations
9 Claims
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1. A system for treating a movement disorder in a human patient comprising:
at least one sensor configured for being in operable communication with an implantable responsive neurostimulator configured to deliver a form of electrical stimulation in response to events detected in physiological signals sensed by sensors, the implantable responsive neurostimulator provided with; a sensor interface configured to receive and continuously monitor at least one physiological signal sensed by the at least one sensor, the at least one physiological signal corresponding to electrical activity of the brain; a signal processor configured for processing the at least one signal to digitize the at least one signal; a detection subsystem configured for analyzing the at least one signal to determine whether a tremor characteristic of an episode of the movement disorder experienced by the human patient is occurring by; measuring an amplitude of the at least one signal; calculating an average amplitude of the at least one signal over a predetermined period of time; comparing the average amplitude to a dynamic threshold that is a fixed offset of a long-term moving average amplitude wherein the long-term moving average amplitude is calculated from data in which no tremors occur; and detecting a tremor event if the calculated average amplitude exceeds the dynamic threshold; a stimulation subsystem configured for generating and then controllably delivering through at least one stimulation electrode the form of electrical stimulation to the patient for so long as the tremor event is detected and to cease delivery of the treatment when the tremor event is no longer detected, wherein measuring, calculating, detecting, and generating and delivering of the electrical stimulation occurs without requiring a previous neurostimulation to have been applied; a memory adapted to store data corresponding to detection by the detection subsystem of a tremor event and data corresponding to the form of electrical stimulation delivered by the stimulation subsystem; and a central processor in operable communication either directly or indirectly with the sensor interface, the signal processor, the detection subsystem, the stimulation subsystem, and the memory. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
Specification