Heart regurgitation method and apparatus

• US 8,597,347 B2
• Filed: 11/15/2007
• Issued: 12/03/2013
• Est. Priority Date: 11/15/2007
• Status: Active Grant

• Current Assignee: Cardiosolutions, Inc.
• Original Assignee: Cardiosolutions, Inc.
• Inventors: Maurer, Christopher W., Wilson, Jonathan E.
• Primary Examiner(s): ANDERSON, GREGORY A
• Application Number:
  US11/940,724
• Publication Number:
  US 20090131849A1
• Time in Patent Office: 2,210 Days
• Field of Search: 623/2.11, 623/1.11
• US Class Current: 623/2.11
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/0441 the shaft being a rigid coil or spiral
• CPC Class Codes: A61B 2017/048 for reducing heart wall tension, e.g. sutures with a pad on each extremity
• CPC Class Codes: A61F 2/246 Devices for obstructing a leak through a native valve in a closed condition

Abstract

A regurgitation implant may comprise a conduit or straw which may be coupled to a shaft. The shaft may be coupled to at least one anchor portion configured to couple the regurgitation implant to native coronary tissue. At least a portion of the conduit may be configured to be disposed proximate a mitral valve such that the regurgitation implant may interact and/or cooperate with at least a portion of the native mitral valve to induce a controlled amount of regurgitation through the conduit and therefore through the mitral valve. The regurgitation through the conduit and the mitral valve may cause the heart to dilute in a manner that is generally consistent with advanced disease of the heart. The amount of regurgitation may therefore be adjusted depending on the desired condition of the heart.

Claims

1. An implant comprising:

a shaft;

at least one anchor coupled to a first end region of said shaft; and

at least one conduit coupled to said shaft and configured to engage against at least a portion of a heart valve between a first and a second heart chamber when said implant is extended through said heart valve, wherein said at least one conduit includes a first and a second open end configured to be disposed within said first and said second heart chambers, respectively such that a controlled amount of regurgitation flows into said first open end, through said heart valve, and out said second open end when said heart valve is in a closed position.

2. The implant of claim 1, wherein said at least one conduit comprises a stent.

3. The implant of claim 1, wherein said at least one conduit comprises a frame.

4. The implant of claim 3, wherein at least a portion of said frame comprises a layer of polytetrafluoroethylene.

5. The implant of claim 1, wherein at least a portion of said conduit is expandable.

6. The implant of claim 5, wherein said expandable portion comprises an inflatable bladder.

7. The implant of claim 5, wherein said expandable portion comprises a shape memory material configured to recoverably deform.

8. The implant of claim 1 comprising a plurality of conduits defining a plurality of passageways configured to induce regurgitation through said heart valve in said closed position.

9. The implant of claim 1, wherein a second end region of said shaft generally opposite from said first end region extends beyond a distal-most end region of said conduit.

10. The implant of claim 9, wherein said second end region of said shaft comprises a driver configured to engage a clamping mechanism of a delivery system.

11. The implant of claim 1, wherein a portion of said conduit extends beyond a second end region of said shaft generally opposite from said first end region.

12. The implant of claim 1, wherein said anchor portion include at least one helical screw.

13. A regurgitation implant comprising:

a shaft;

at least one anchor coupled to an end region of said shaft; and

at least one conduit coupled to said shaft configured to engage against at least a portion of at least one cusp of a heart valve when said device is extended through said heart valve, so as to at least partially restrict a flow of blood through said heart valve when said heart valve is in a closed position, wherein said at least one conduit defines at least one passageway configured to extend through said heart valve and including a first open end configured to be disposed within a first heart chamber and a second open end configured to be disposed within a second heart chamber such that a controlled amount of regurgitation flows into said first open end, through said heart valve, and out said second open end when said heart valve is in said closed position.

14. The regurgitation implant of claim 13, wherein at least a portion of said conduit is expandable.

15. The regurgitation implant of claim 14, wherein said expandable portion comprises an inflatable bladder.

16. The regurgitation implant of claim 14, wherein said expandable portion comprises a shape memory material configured to recoverably deform.

17. A method according to claim 14, wherein percutaneously inserting said at least partially collapsed regurgitation implant comprises inserting said regurgitation implant into a lumen of a catheter and delivering said regurgitation implant to said left ventricle via said catheter.

18. A method of inducing regurgitation comprising:

providing a regurgitation implant comprising at least one anchor portion and conduit coupled to a shaft;

percutaneously inserting said regurgitation implant into a heart; and

securing said regurgitation implant within said heart such that said at least one conduit extends through a heart valve between two heart chambers and engages against at least a portion of at least one cusp of said heart valve to define at least one passageway through said heart valve configured to induce a controlled amount of regurgitation through said heart valve in a closed position.

19. The method of claim 18 further comprising:

at least partially collapsing said regurgitation implant;

percutaneously delivering said at least partially collapsed regurgitation implant proximate said heart; and

expanding said at least partially collapsed regurgitation implant.