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Coating of fast absorption or dissolution

  • US 8,597,673 B2
  • Filed: 12/13/2006
  • Issued: 12/03/2013
  • Est. Priority Date: 12/13/2006
  • Status: Expired due to Fees
First Claim
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1. A coating on an implantable device, the coating comprising a phosphoryl choline polymer, wherein about 50 wt % or more of the coating can absorb or dissolve within 24 hours after implantation,wherein the phosphoryl choline polymer comprises at least one phosphoryl choline moiety and at least one moiety derived from a biocompatible polymer,wherein the biocompatible polymer comprises poly(ester amide), poly(lactic acid), poly(glycolic acid), poly(caprolactone), poly(dioxanone), or poly(ester amide-2,2,6,6-tetramethyl-1-piperidinyloxy) (PEA-TEMPO),wherein phosphoryl choline polymer comprises a fragment having the formula of

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