Coating of fast absorption or dissolution
First Claim
1. A coating on an implantable device, the coating comprising a phosphoryl choline polymer, wherein about 50 wt % or more of the coating can absorb or dissolve within 24 hours after implantation,wherein the phosphoryl choline polymer comprises at least one phosphoryl choline moiety and at least one moiety derived from a biocompatible polymer,wherein the biocompatible polymer comprises poly(ester amide), poly(lactic acid), poly(glycolic acid), poly(caprolactone), poly(dioxanone), or poly(ester amide-2,2,6,6-tetramethyl-1-piperidinyloxy) (PEA-TEMPO),wherein phosphoryl choline polymer comprises a fragment having the formula of
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Abstract
A coating of fast absorption or fast dissolution on an implantable device and methods of making and using of the coating are provided.
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Citations
8 Claims
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1. A coating on an implantable device, the coating comprising a phosphoryl choline polymer, wherein about 50 wt % or more of the coating can absorb or dissolve within 24 hours after implantation,
wherein the phosphoryl choline polymer comprises at least one phosphoryl choline moiety and at least one moiety derived from a biocompatible polymer, wherein the biocompatible polymer comprises poly(ester amide), poly(lactic acid), poly(glycolic acid), poly(caprolactone), poly(dioxanone), or poly(ester amide-2,2,6,6-tetramethyl-1-piperidinyloxy) (PEA-TEMPO), wherein phosphoryl choline polymer comprises a fragment having the formula of
Specification