Glaucoma drainage devices including vario-stable valves and associated systems and methods

• US 8,603,024 B2
• Filed: 12/12/2011
• Issued: 12/10/2013
• Est. Priority Date: 12/12/2011
• Status: Active Grant

• Current Assignee: Alcon Research, LLC (Alcon Incorporated)
• Original Assignee: Alcon Research Limited (Nestle SA)
• Inventors: Bhm, Sebastian, Field, Leslie A., Rickard, Matthew J. A.
• Primary Examiner(s): HAND, MELANIE JO
• Application Number:
  US13/316,717
• Publication Number:
  US 20130150776A1
• Time in Patent Office: 729 Days
• Field of Search: 604/8, 604/9, 606 4- 6
• US Class Current: 604/9
• CPC Class Codes: A61B 3/16 for measuring intraocular pressure, e.g. tonometers
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Glaucoma drainage devices including vario-stable valves and associated systems and methods are disclosed. A glaucoma drainage device includes a drainage lumen and a valve system coupled to the drainage lumen to control the flow of fluid through the drainage lumen. The valve system includes an adjustable valve with a diaphragm that is in communication with the drainage lumen and is movable to occupy varying amounts of the drainage lumen. In some embodiments, the valve system is maintained in a desired position without the use of power such that power is only needed when changing a position of the adjustable valve.

Claims

1. A valve system for use within an ophthalmic device, the valve system comprising:

an adjustable valve having;

a housing defining a cavity; and

a movable diaphragm bounding at least one side of the cavity;

a fluid reservoir in fluid communication with the cavity of the adjustable valve;

an actuator for controlling a flow of fluid between the fluid reservoir and the cavity of the adjustable valve, the actuator comprising a voltage source, a pair of electrodes, an actuator fluid and a bubble-generating system configured to generate bubbles by converting at least a portion of the actuator fluid to a gas, wherein one of the electrodes is positioned within the fluid reservoir and the other electrode is positioned outside of the fluid reservoir;

a first check valve positioned between the fluid reservoir and the cavity of the adjustable valve along a first fluid passageway, the first check valve preventing fluid flow from the fluid reservoir to the cavity of the adjustable valve; and

a second check valve positioned between the fluid reservoir and the cavity of the adjustable valve along a second fluid passageway, the second check valve preventing fluid flow from the cavity of the adjustable valve to the fluid reservoir.

2. The valve system of claim 1, wherein the pair of electrodes are positioned within the fluid reservoir.

3. The valve system of claim 1, wherein the other electrode is positioned within the cavity of the adjustable valve.

4. The valve system of claim 1, wherein the fluid reservoir is formed of a material that defines a constant volume cavity during operation.

5. The valve system of claim 1, wherein the fluid reservoir is formed of a flexible material that defines a variable volume cavity during operation.

6. The valve system of claim 1 wherein at least one of the first and second check valves is a converging pathway.

7. The valve system of claim 1 wherein at least one of the first and second check valves is a diverging pathway.

8. The valve system of claim 1, further comprising:

a first bubble chamber positioned adjacent the first fluid passageway such that a diaphragm of the first adjustable component is movable between a first position that occupies a first amount of the first fluid passageway and a second position that occupies a second amount of the first fluid passageway, the second amount being greater than the first amount.

9. The valve system of claim 8, wherein the first bubble chamber is configured to control fluid flow from the cavity of the adjustable valve to the fluid reservoir.

10. The valve system of claim 9, wherein the first check valve is positioned between the first bubble chamber and the fluid reservoir.

11. The valve system of claim 9, wherein the first check valve is positioned between the first bubble chamber and the cavity of the adjustable valve.

12. The valve system of claim 9, wherein the first check valve is positioned between the first bubble chamber and fluid reservoir and a third check valve is positioned between the first bubble chamber and the adjustable valve, the third check valve also preventing flow from the fluid reservoir to the adjustable valve.

13. The valve system of claim 8, further comprising:

a second bubble chamber positioned adjacent the second fluid passageway such that a diaphragm of the second bubble chamber is movable between a first position that occupies a first amount of the second fluid passageway and a second position that occupies a second amount of the second fluid passageway, the second amount being greater than the first amount.

14. The valve system of claim 13, wherein the second bubble chamber is configured to control fluid flow from the fluid reservoir to the cavity of the adjustable valve.

15. The valve system of claim 14, wherein the second check valve is positioned between the second bubble chamber and the cavity of the adjustable valve.

16. The valve system of claim 14, wherein the second check valve is positioned between the second bubble chamber and the fluid reservoir.

17. The valve system of claim 14, wherein the second check valve is positioned between the second bubble chamber and fluid reservoir and a third check valve is positioned between the second bubble chamber and the adjustable valve, the third check valve also preventing flow from the adjustable valve to the fluid reservoir.

18. The valve system of claim 1, wherein the valve system is configured to maintain the diaphragm in a desired position after actuation of an actuator configured to move the diaphragm has ceased.

19. The valve system of claim 1, wherein the valve system is configured to pump aqueous humor from an anterior chamber of an eye.

20. The valve system of claim 19, wherein the valve system is configured to be activated when in the vicinity of an external power source and deactivated when not in the vicinity of an external power source.