Use of an adhesive to treat intraluminal bleeding

• US 8,603,138 B2
• Filed: 10/04/2006
• Issued: 12/10/2013
• Est. Priority Date: 10/04/2006
• Status: Active Grant

• Current Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Faller, Craig N., Haberstitch, Wells D., Korvick, Donna L., Thompson, Bennie, Turner, Douglas J., Nalagatla, Anil K., Shelton, Frederick E. IV
• Primary Examiner(s): TYSON, MELANIE RUANO
• Application Number:
  US11/538,571
• Publication Number:
  US 20090143818A1
• Time in Patent Office: 2,624 Days
• Field of Search: 606213-221, 606151-158, 604/35
• US Class Current: 606/216
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/308 with suction cups

Abstract

A surgical device to stanch the flow of blood is disclosed. The surgical device can place an implantable adhesive over or around varices or other bleeders. The surgical device has a vacuum system for capturing tissue and an adhesive system to apply adhesive to the captured tissue. A vacuum chamber is used to contact tissue and contains a chamber therein for the reception of tissue. An adhesive applicator is provided within the vacuum chamber and moves longitudinally therein to apply adhesive to tissue. The surgical device can apply an adhesive patch to tissue or inject adhesive into tissue. Alternately, an adhesive actuator and a chemical agent can be dispensed to tissue within the vacuum chamber.

Claims

1. A surgical device for staunching the flow of blood from tissue, the surgical device comprising:

a) an adhesive implantable in a patient'"'"'s body;

b) a vacuum system for capturing tissue therein, the vacuum system comprising;

(i) a flexible shaft, wherein the flexible shaft has a distal end,

(ii) a vacuum cannula, wherein the vacuum cannula is disposed within and runs parallel to the flexible shaft, wherein the vacuum cannula is slidable within the flexible shaft, and

(iii) a vacuum head disposed at the distal end of the vacuum cannula, wherein the vacuum head is configured to form a vacuum chamber for the reception of tissue therein, wherein the vacuum cannula and the vacuum head are configured to advance together from an interior position within the flexible shaft to an exterior position where the vacuum head is located distal to the distal end of the flexible shaft,

wherein the vacuum head is configured to collapse in the interior position to a collapsed configuration, wherein the vacuum head is configured to expand to an expanded configuration in the exterior position when extended from the distal end of the flexible shaft,

wherein the vacuum head has a first circumference in the expanded configuration, wherein the distal end of the flexible shaft has a second circumference, and wherein the first circumference is greater than the second circumference; and

c) an adhesive system for applying the adhesive to tissue captured within the vacuum system to staunch the flow of blood, the adhesive system comprising an adhesive cannula, wherein the adhesive cannula is coaxially disposed within and runs parallel to the vacuum cannula, wherein the adhesive system comprises an adhesive tip at a distal end of the adhesive cannula, wherein the adhesive cannula is movable relative to the vacuum cannula such that the adhesive cannula is operable to move the adhesive tip from a first position within the vacuum cannula and proximal to the distal end of the flexible shaft to a second position distal of the flexible shaft, wherein the vacuum system and the adhesive system are configured and positioned relative to each other such that the adhesive system is operable to apply the adhesive to tissue captured within the vacuum system and thereby form a protective cap with the adhesive to staunch the flow of blood from the tissue captured within the vacuum system.

2. The surgical device of claim 1 wherein the adhesive is polymerizable.

3. The surgical device of claim 2 wherein the adhesive is one or more selected from the group of:

a) a polymerizable monomer,

b) a polymerizable 1,1,1,1-disubstituted ethylene monomer, and

c) a cyanoacrylate formulation.

4. The surgical device of claim 2 wherein a polymerization agent for the adhesive is one or more of the polymerization agents selected from the group consisting of:

a) natural body moisture,

b) saline, and

c) an adhesion initiator compound.

5. The surgical device of claim 1 wherein the vacuum system further comprises a vacuum source attachable to the surgical device.

6. The surgical device of claim 1 wherein the vacuum head has a third circumference in the collapsed configuration, wherein the third circumference is less than the second circumference.

7. The surgical device of claim 6 wherein the vacuum head is transparent.

8. The surgical device of claim 6 wherein the vacuum head is a cone in the expanded position.

9. The surgical device of claim 6 wherein the vacuum head is constructed from at least one piece of spring material having a natural position, wherein the natural position is selected from the group consisting of:

a) a naturally open position,

b) a naturally partially open position, and

c) a naturally closed position.

10. The surgical device of claim 9 wherein the at least one piece of spring material has at least one fold.

11. The surgical device of claim 9 wherein the at least one piece of spring material is on or more spring material selected from the group consisting of:

a) nitinol,

b) mylar,

c) polytetraflouroethylene,

d) nylon, and

e) silicone.

12. The surgical device of claim 6 wherein the vacuum head is an openable and closable umbrella having at least one rib structure and at least one deformable film operably attached to the at least one rib structure.

13. The surgical device of claim 12 wherein the at least one rib structure is selected from the group consisting of:

a) a rigid folding rib structure,

b) a deformable spring rib structure,

c) a rib structure molded as a thicker part of the deformable film, and

d) a spring attached to a folding rib structure to open the folding rib structure.

14. The surgical device of claim 12 wherein the at least one deformable film is constructed from one or more materials selected from the group consisting of:

natural rubber, artificial rubber, polyethelene, polypropelene, polytetraflouroethylene, paper, and surgical fabric.

15. The surgical device of claim 6 wherein the adhesive system further comprises a pump, wherein the adhesive cannula is operatively attached between the pump and the vacuum chamber, wherein when the adhesive system is actuated, the pump is operable to deliver adhesive to tissue captured within the vacuum system through the adhesive cannula.

16. The surgical device of claim 15 wherein the adhesive tip is operably disposed within the vacuum head, the adhesive tip having a discharge port for applying adhesive to tissue and being moveable within the vacuum head towards and away from tissue captured within the vacuum head.

17. The surgical device of claim 16 wherein the adhesive tip has a sharp tip for piercing tissue, wherein the discharge port is located in the sharp tip for dispensing adhesive into tissue captured within the vacuum system.

18. The surgical device of claim 15 wherein the adhesive system includes one or more chemical agents applied with the adhesive to tissue within the vacuum chamber, wherein the chemical agent is one or more chemical agents selected from the group consisting of:

an adhesive initiator, an image enhancement media, an anesthetic, a sclerotic agent, a necrosing agent, a drug, and a medicament.

19. The surgical device of claim 18 wherein the adhesive system further comprises a mixer between the pump and the discharge port, wherein the mixer mixes the chemical agent with the adhesive prior to applying the mixture of adhesive and chemical agent to tissue captured in the vacuum head.