Irradiated stent coating
First Claim
1. An expandable intraluminal graft for use within a body passageway including a body member, a intermediate compound, and biological agent, said intermediate compound, said at least one biological agent, and mixtures thereof coated on at least a portion of the body member, said body member having first and second ends and a wall surface disposed between said first and second ends defining a longitudinal axis of said body member, said body member having a first cross-sectional shape having a first cross-sectional area which permits intraluminal delivery of said body member into the body cavity, and a second expanded cross-sectional shape having a second cross-sectional area which is greater than said first cross-sectional area, said biological agent at least partially coated on or secured to the surface of said body member, said biological agent including two or more compounds selected from the group consisting of Trapidil, GM-CSF, Taxol, rapamycin, and mixtures thereof, said biological agent including Trapidil, said intermediate compound at least partially securing said biological agent to said body member, said intermediate compound at least partially encapsulating said biological agent in said intermediate compound, and combinations thereof.
2 Assignments
0 Petitions
Accused Products
Abstract
An expandable stent for use within a body passageway having a body member with two ends and a wall surface disposed between the ends. The body member has a first diameter to permit delivery of the body member into a body passageway and a second expanded diameter. The surface of the stent is coated with a biological agent and a polymer which controls the release of the biological agent.
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Citations
44 Claims
- 1. An expandable intraluminal graft for use within a body passageway including a body member, a intermediate compound, and biological agent, said intermediate compound, said at least one biological agent, and mixtures thereof coated on at least a portion of the body member, said body member having first and second ends and a wall surface disposed between said first and second ends defining a longitudinal axis of said body member, said body member having a first cross-sectional shape having a first cross-sectional area which permits intraluminal delivery of said body member into the body cavity, and a second expanded cross-sectional shape having a second cross-sectional area which is greater than said first cross-sectional area, said biological agent at least partially coated on or secured to the surface of said body member, said biological agent including two or more compounds selected from the group consisting of Trapidil, GM-CSF, Taxol, rapamycin, and mixtures thereof, said biological agent including Trapidil, said intermediate compound at least partially securing said biological agent to said body member, said intermediate compound at least partially encapsulating said biological agent in said intermediate compound, and combinations thereof.
Specification