Compositions and methods for biological remodeling with frozen particle compositions
First Claim
Patent Images
1. A frozen particle composition, comprising:
- one or more frozen hydrogen oxide particles coated in at least one biological remodeling agent including one of collagenase, elastase, collagen, keratin, elastin, fibrin, heparin, fibrinogen, globulin, thrombin, glutaraldehyde-crosslinked pericardium, hyaluronic acid, hydroxylapatite, keratin, ligament, nitinol, polyethylene, polyethylene glycol diacrylate, polyethylene terephthalate fiber, polytetrafluoroethylene, polyglycolic acid, tendon, hyaluronate, chitin, chitosan, polyaldehyde gluronate, Factor XIII, Factor XII, silk, nylon, polyurethane, glycosaminoglycan, poly(α
-hydroxyacid), selectin, or glutaraldehyde.
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Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
231 Citations
15 Claims
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1. A frozen particle composition, comprising:
one or more frozen hydrogen oxide particles coated in at least one biological remodeling agent including one of collagenase, elastase, collagen, keratin, elastin, fibrin, heparin, fibrinogen, globulin, thrombin, glutaraldehyde-crosslinked pericardium, hyaluronic acid, hydroxylapatite, keratin, ligament, nitinol, polyethylene, polyethylene glycol diacrylate, polyethylene terephthalate fiber, polytetrafluoroethylene, polyglycolic acid, tendon, hyaluronate, chitin, chitosan, polyaldehyde gluronate, Factor XIII, Factor XII, silk, nylon, polyurethane, glycosaminoglycan, poly(α
-hydroxyacid), selectin, or glutaraldehyde.- View Dependent Claims (2, 3, 4, 5, 6, 7, 10, 11, 12, 13, 14, 15)
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8. A frozen particle composition, comprising:
one or more frozen particles including dimethylsulfoxide, cyanoacrylate, polyethylene glycol, and coated in at least one biological remodeling agent including at least one of collagenase, elastase, collagen, keratin, elastin, fibrin, heparin, fibrinogen, globulin, thrombin, glutaraldehyde-crosslinked pericardium, hyaluronic acid, hydroxylapatite, keratin, ligament, nitinol, polyethylene, polyethylene glycol diacrylate, polyethylene terephthalate fiber, polytetrafluoroethylene, polyglycolic acid, tendon, hyaluronate, chitin, chitosan, polyaldehyde gluronate, Factor XIII, Factor XII, silk, nylon, polyurethane, glycosaminoglycan, poly(α
-hydroxyacid), selectin, or glutaraldehyde.
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9. A frozen particle composition, comprising:
one or more frozen particles including at least one alcohol, and coated in at least one of collagenase, elastase, collagen, keratin, elastin, fibrin, heparin, fibrinogen, globulin, thrombin, glutaraldehyde-crosslinked pericardium, hyaluronic acid, hydroxylapatite, keratin, ligament, nitinol, polyethylene, polyethylene glycol diacrylate, polyethylene terephthalate fiber, polytetrafluoroethylene, polyglycolic acid, tendon, hyaluronate, chitin, chitosan, polyaldehyde gluronate, Factor XIII, Factor XII, silk, nylon, polyurethane, glycosaminoglycan, poly(α
-hydroxyacid), selectin, or glutaraldehyde.
Specification