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Nanoshell therapy

  • US 8,603,530 B2
  • Filed: 06/14/2006
  • Issued: 12/10/2013
  • Est. Priority Date: 06/14/2006
  • Status: Expired due to Fees
First Claim
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1. A medical device for treating or ameliorating a vascular condition, comprising:

  • (a) nano-constructs that comprise a core material and a carbon or conducting polymer nanoshell formed on the core material, said carbon or conducting polymer nanoshell having a thickness between about 2 nm to about 100 nm and(b) delivery means for delivering the nano-constructs to a target tissue of a subject;

    wherein the nano-constructs are capable of absorbing an energy from an electromagnetic radiation or energy from a fluctuating electromagnetic field and translating the energy into heat, and wherein the nano-constructs comprise targeting molecules on a surface of the nano-constructs, and the targeting molecules are selected from the group consisting of YIGSR, peptides and antibodies to IIbIIIa, hyaluronic acid, ICAM-1, ICAM-2, ICAM-3, thrombospondin osteopontin, N-CAM, PECAM-1, IgCAM, oligonucleotide aptamers, selectins, cadherins, and combinations thereof.

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