Cardiac waveform template creation, maintenance and use

• US 8,606,357 B2
• Filed: 12/22/2008
• Issued: 12/10/2013
• Est. Priority Date: 05/28/2003
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Lee, Kent, Sweeney, Robert
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US12/341,558
• Publication Number:
  US 20090105778A1
• Time in Patent Office: 1,814 Days
• Field of Search: 607/27, 607/28
• US Class Current: 607/28
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

The present disclosure describes methods and systems for creating, adjusting, and using cardiac waveform morphology templates. The morphology templates include target regions associated with features of cardiac waveforms. The target regions may be adjusted based on relationships between the target regions and features of detected cardiac waveforms associated with the target regions. The templates may be used to analyze cardiac waveforms to classify or monitor various waveform morphologies. Templates may be created or eliminated based on a frequency of use. According to one approach, template creation involves providing target regions defined by one or more characteristics. The target regions are adjusted based on detected cardiac waveform features having similar characteristics. A template may be created using the target regions adjusted by this process.

Claims

1. A method of operating an implantable cardiac device comprising:

associating one or more target region attributes with each of a plurality of target regions, the one or more target region attributes including at least sampling rate and each target region having a location, a time dimension, and an amplitude dimension;

detecting a cardiac waveform feature;

adjusting at least one target region of the plurality of target regions based on a location of the detected feature of the cardiac waveform and compatibility between the attributes of the at least one target region and attributes of the waveform feature;

delivering a cardiac pacing pulse during a cardiac cycle;

detecting a subsequent cardiac waveform after delivery of the pacing pulse;

determining a cardiac pacing response to the pacing pulse based on whether features of the subsequent cardiac waveform fall within the plurality of target regions; and

adjusting a pacing energy of the cardiac device based on the cardiac pacing response.

2. The method of claim 1, wherein adjusting the at least one target region further comprises:

determining a location of the waveform feature relative to the location of the at least one target region; and

adjusting the location of the at least one target region toward the location of the waveform feature.

3. The method of claim 1, further comprising:

determining a location of the waveform feature relative to one or both of the amplitude dimension of the at least one target region and the time dimension of the at least one target region; and

adjusting one or both of the amplitude dimension of the target region and the time dimension of the target region based on the location of the waveform feature.

4. The method of claim 1, further comprising:

determining a variability of a location of the waveform feature; and

adjusting one or both of the amplitude dimension and the time dimension of the at least one target region based on the variability of the location of the waveform feature.

5. The method of claim 1, wherein the features of the cardiac waveform comprise a positive peak and a negative peak.

6. The method of claim 1, wherein:

the plurality of target regions are associated with a fusion waveform; and

determining the cardiac pacing response comprises detecting a fusion beat.

7. The method of claim 1, wherein:

the plurality of target regions are associated with a captured waveform; and

determining the cardiac pacing response comprises detecting a captured beat.

8. The method of claim 1, wherein adjusting the at least one target region is limited by one or both of a predetermined amplitude boundary and a predetermined time boundary.

9. The method of claim 8, wherein the predetermined amplitude boundary is an upper boundary.

10. The method of claim 8, wherein the predetermined time boundary is a lower boundary.

11. The method of claim 1, wherein adjusting the at least one target region is limited by one or both of a predetermined range of the-time dimension and a predetermined range of the amplitude dimension.

12. An implantable cardiac device, comprising:

pacing therapy circuitry configured to deliver a pacing pulse to a heart during each of a plurality of cardiac cycles;

sensing circuitry configured to sense a cardiac waveform after delivery of each pacing pulse; and

a control system configured to associate and provide one or more target region attributes with each of a plurality of target regions, the one or more target region attributes including at least sampling rate, each target region having a location, a time dimension, and an amplitude dimension, the control system configured to adjust at least one target region of the plurality of target regions based on a location of at least one sensed cardiac waveform feature and compatibility between attributes of the at least one target region and attributes of the at least one sensed cardiac waveform feature,

the control system configured to, for a subsequent cardiac cycle, determine if features of a subsequently sensed cardiac waveform fall within the plurality of target regions and to determine the cardiac pacing response based on whether the cardiac waveform features of the subsequently sensed cardiac waveform fall within the plurality of target regions.

13. The device of claim 12, wherein the control system is configured to detect fusion based on whether the cardiac waveform features of the subsequently sensed cardiac waveform fall within the plurality of target regions.

14. The device of claim 12, wherein the at least one cardiac waveform feature comprises a positive waveform peak or a negative waveform peak.

15. The device of claim 14, wherein the control system is further configured to adjust the one target region based on locations of the positive waveform peak or the negative waveform peak.

16. The device of claim 15, wherein adjustment of the at least one target region is limited by one or both of a predetermined range of the time dimension and a predetermined range of the amplitude dimension.

17. The device of claim 12, wherein adjustment of the at least one target region is limited by one or both of a predetermined amplitude boundary and a predetermined time boundary.

18. The device of claim 17, wherein the predetermined amplitude boundary is an upper boundary.

19. The device of claim 17, wherein the predetermined time boundary is a lower boundary.

20. An implantable medical device, comprising:

means for associating and providing one or more target region attributes with each of a plurality of target regions, the one or more target region attributes including at least sampling rate and each target region having a location, a time dimension, and an amplitude dimension;

means for detecting a cardiac waveform feature;

means for adjusting at least one target region of the plurality of target regions based on a location of the detected cardiac waveform feature and compatibility between attributes of the at least one target region and attributes of the cardiac waveform feature;

means for delivering-a cardiac pacing pulse during a cardiac cycle;

means for detecting features of a subsequent cardiac waveform after delivery of the pacing pulse;

means for determining a cardiac pacing response to the pacing pulse based on whether features of the subsequent cardiac waveform fall within the plurality of target regions; and

means for adjusting a pacing energy of the cardiac device based on the cardiac pacing response.