System and method for sustained baroreflex stimulation
First Claim
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1. A medical device, comprising:
- an implantable baroreflex activation device configured to be implanted on or in a blood vessel of a patient proximate a baroreceptor in a wall of the blood vessel; and
an implantable controller coupled to the implantable baroreflex activation device and configured to deliver a stimulation signal to the baroreceptor via the implantable baroreflex activation device, the controller including stimulus regimen stored in a memory accessible by the controller, the stimulus regimen programmed to vary an intensity of the stimulation signal to maintain responsiveness of the baroreceptor to the stimulation signal.
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Abstract
The present invention comprises a medical device having a baroreflex stimulator to generate a stimulation signal, the stimulation signal being adapted to stimulate a baroreflex, and a controller to communicate with the baroreflex stimulator and implement a baroreflex stimulus regimen to vary an intensity of the baroreflex stimulation provided by the stimulation signal to maintain stimulation efficacy.
438 Citations
20 Claims
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1. A medical device, comprising:
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an implantable baroreflex activation device configured to be implanted on or in a blood vessel of a patient proximate a baroreceptor in a wall of the blood vessel; and an implantable controller coupled to the implantable baroreflex activation device and configured to deliver a stimulation signal to the baroreceptor via the implantable baroreflex activation device, the controller including stimulus regimen stored in a memory accessible by the controller, the stimulus regimen programmed to vary an intensity of the stimulation signal to maintain responsiveness of the baroreceptor to the stimulation signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method, comprising:
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implanting a baroreflex activation device on or in a blood vessel of a patient proximate a baroreceptor in a wall of the blood vessel; implanting a controller within the patient, the controller coupled to the baroreflex activation device, the controller having a stimulus regimen stored therein; and causing the controller to deliver a stimulation signal to the baroreceptor via the baroreflex activation device, the stimulation signal delivered according to the stimulus regimen, the stimulus regimen programmed to change at least one parameter of the stimulation signal such that the stimulation ranges within a range from a first stimulation level to a second stimulation level so as to maintain responsiveness of the baroreceptor to the stimulation signal. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification