Dynamic anthropomorphic cardiovascular phantom
First Claim
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1. A cardiovascular flow system, comprising:
- (a) a model of a cardiovascular system, the model including cardiac anatomy inclusive of a pulmonary artery that crosses a coronary artery tree of the cardiac anatomy;
(b) a pump system for enabling a carrier fluid to be propagated through the model;
(c) an ECG simulator system in communicative connection with the pump system, the ECG simulator system being adapted to create and transmit a simulated ECG signal, the ECG simulator system using a signal received from the pump system to adjust the simulated ECG signal transmitted from the ECG simulator system; and
(d) an injection port to enable an injection fluid to be injected into the model, the injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model;
wherein, as the carrier fluid and the injection fluid flow through the model as a result of the pump system, at least the injection fluid is detectable by an imaging system as the injection fluid flows through at least one region of interest of the model.
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Abstract
A cardiovascular flow system includes: a cardiovascular model system, a pump system in fluid connection with the cardiovascular model system, and an ECG simulator in communicative connection with the pump system. The ECG simulator system is adapted to create and transmit a simulated ECG signal. The ECG simulator system uses a signal received from the pump system to adjust the simulated ECG signal transmitted from the ECG simulator system. The cardiovascular flow system further includes an injection port adapted to be placed in fluid connection with an injector to inject at least one fluid into the system.
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Citations
31 Claims
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1. A cardiovascular flow system, comprising:
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(a) a model of a cardiovascular system, the model including cardiac anatomy inclusive of a pulmonary artery that crosses a coronary artery tree of the cardiac anatomy; (b) a pump system for enabling a carrier fluid to be propagated through the model; (c) an ECG simulator system in communicative connection with the pump system, the ECG simulator system being adapted to create and transmit a simulated ECG signal, the ECG simulator system using a signal received from the pump system to adjust the simulated ECG signal transmitted from the ECG simulator system; and (d) an injection port to enable an injection fluid to be injected into the model, the injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model; wherein, as the carrier fluid and the injection fluid flow through the model as a result of the pump system, at least the injection fluid is detectable by an imaging system as the injection fluid flows through at least one region of interest of the model. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of simulating flow of an injection fluid through a mammalian cardiovascular system, the steps of the method comprising:
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(a) providing a model of a cardiovascular system of a mammal, the model comprising a cardiac anatomy and a pulmonary artery crossing the cardiac anatomy, the model further comprising an injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model; (b) pumping a carrier fluid through the model to enable propagation of the carrier fluid through the model inclusive of the cardiac anatomy and the pulmonary artery; (c) configuring a desired cardiac output and heart rate of the cardiovascular system by adjusting at least a stroke volume and a stroke frequency of the pumping; (d) generating an ECG signal for the cardiovascular system that is synchronized with a trigger signal associated with the pumping; (e) injecting the injection fluid into the model via the injection port; and (f) detecting the injection fluid in at least one region of interest within the model as the carrier fluid and the injection fluid flow through the model as a result of the pumping. - View Dependent Claims (21, 22, 23, 24, 25)
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26. A cardiovascular flow system, comprising:
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(a) a model of a cardiovascular system, the model comprising a cardiac anatomy and a pulmonary artery crossing the cardiac anatomy; (b) a pump system for enabling a carrier fluid to be propagated through the model inclusive of the cardiac anatomy and the pulmonary artery; (c) an injection port to enable an injection fluid to be injected into the model, the injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model; and (d) a kidney system in fluid connection with the model, the kidney system comprising a first pump system to pump fresh carrier fluid into the model and a second pump system to filter at least one of the injection fluid and an other fluid out of the model; wherein, as the carrier fluid and the injection fluid flow through the model as a result of the pump system, at least the injection fluid is detectable by an imaging system as the injection fluid flows through at least one region of interest of the model. - View Dependent Claims (27, 28)
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29. A cardiovascular flow system, comprising:
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(a) a model of a cardiovascular system, the model comprising a cardiac anatomy and a pulmonary artery crossing the cardiac anatomy; (b) a pump system for enabling a carrier fluid to be propagated through the model inclusive of the cardiac anatomy and the pulmonary artery; (c) an injection port to enable an injection fluid to be injected into the model, the injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model; and (d) a pressure relief system to prevent pressure within the cardiovascular flow system from exceeding a predetermined pressure; wherein, as the carrier fluid and the injection fluid flow through the model as a result of the pump system, at least the injection fluid is detectable by an imaging system as the injection fluid flows through at least one region of interest of the model. - View Dependent Claims (30)
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31. A cardiovascular flow system, comprising:
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(a) a model of a cardiovascular system for simulating anatomy and physiology, the model including cardiac anatomy inclusive of a pulmonary artery that crosses a coronary tree of the cardiac anatomy; (b) a pump system for enabling a carrier fluid to be propagated through the model; (c) an ECG simulator system in communicative connection with the pump system, the ECG simulator system being adapted to create and transmit a simulated ECG signal, the ECG simulator system using a signal received from the pump system to adjust the simulated ECG signal transmitted from the ECG simulator system; and (d) an injection port to enable an injection fluid to be injected into the model, the injection port adapted to be placed in fluid connection with an injector to inject the injection fluid into the model; wherein as the carrier fluid and the injection fluid flow through the model as a result of the pump system, the cross of the coronary tree by the pulmonary artery enables acquisition of imaging scans thereof in which an enhancement pattern mimics that of a pulmonary trunk of a human cardiovascular system.
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Specification