Impedimetric sensor and applications thereof
First Claim
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1. An impedimetric biosensor for directly determining the presence of analytes in a sample characterised in that it comprises:
- i) an insulating substrate or non-insulating substrate covered with an insulating layer,ii) at least, a pair of chemically inert interdigitated electrodes and formed with a highly electrically conductive material, disposed on the substrate and each pair of digits separated, but not covered, byiii) a barrier made of an insulating material into which welding points open for external wire connection to each of the electrodes, wherein the insulating barrier comprises a thickness of the insulating layer which defines the height of the barrier separating two adjacent digits, the thickness comprising from 50% to 150% of the distance separating the centres of the pair of consecutive interdigitated electrodes, andiv) chemically immobilised receptor molecules on the surface of the insulating material of the barriers.
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Abstract
A highly sensitive impedimetric sensor in which the highly conductive electrodes are separated by a barrier of insulating material is disclosed. The sensor is used to determine directly the presence of analytes in a biological sample of human, veterinary or environmental origin.
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16 Claims
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1. An impedimetric biosensor for directly determining the presence of analytes in a sample characterised in that it comprises:
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i) an insulating substrate or non-insulating substrate covered with an insulating layer, ii) at least, a pair of chemically inert interdigitated electrodes and formed with a highly electrically conductive material, disposed on the substrate and each pair of digits separated, but not covered, by iii) a barrier made of an insulating material into which welding points open for external wire connection to each of the electrodes, wherein the insulating barrier comprises a thickness of the insulating layer which defines the height of the barrier separating two adjacent digits, the thickness comprising from 50% to 150% of the distance separating the centres of the pair of consecutive interdigitated electrodes, and iv) chemically immobilised receptor molecules on the surface of the insulating material of the barriers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification