Handheld electrochemical sensor

• US 8,608,923 B2
• Filed: 10/25/2010
• Issued: 12/17/2013
• Est. Priority Date: 06/12/2006
• Status: Active Grant

• Current Assignee: Anhong Zhou
• Original Assignee: Utah State University
• Inventors: Zhou, Anhong, Dou, Hui-Fang
• Primary Examiner(s): LEONG, SUSAN DANG
• Application Number:
  US12/911,330
• Publication Number:
  US 20110036714A1
• Time in Patent Office: 1,149 Days
• Field of Search: 204/230.8, 204400-435, 205775-7945
• US Class Current: 204/406
• CPC Class Codes: G01N 27/48 using polarography, i.e. measuring changes in current under a slowly-varying voltage

Abstract

A handheld sensor device is provided for measuring an ion concentration in a solution. The solution is in an electrochemical cell that includes a counter electrode, a working electrode, and a reference electrode. The sensor includes a control amplifier configured to provide a current through the counter electrode and the working electrode so as to maintain a predetermined voltage between the working electrode and the reference electrode. The sensor also includes a current amplifier configured to measure the current provided through the counter electrode and the working electrode. In one embodiment, the sensor also includes a direct digital frequency synthesizer (DDFS) including a phase accumulator. The DDFS is configured to selectively generate a waveform specified by an electrochemical technique such as square wave voltammetry, cyclic voltammetry, linear sweep voltammetry, differential-pulse polarography, normal-pulse polarography, or other known electrochemical techniques.

Claims

1. A handheld sensor device for measuring an ion concentration in a solution in an electrochemical cell that includes a counter electrode, a working electrode, and a reference electrode, the handheld sensor device comprising:

a function generator configured to generate a waveform specified by an electrochemical technique; and

a potentiostat integrated with the function generator in a single, portable device, the potentiostat comprising;

a control amplifier configured to provide a current through the counter electrode and the working electrode so as to maintain a predetermined voltage between the working electrode and the reference electrode; and

a current amplifier configured to measure the current provided through the counter electrode and the working electrode,

wherein the current amplifier is configured to measure the current throughout an entire range comprising approximately 100 pA to approximately 2 mA.

2. The handheld sensor device of claim 1, further comprising a microprocessor configured to allow a user to selectively specify one or more parameters for the waveform generated by the function generator.

3. The handheld sensor device of claim 1, wherein the function generator comprises a direct digital frequency synthesizer (DDFS) comprising a phase accumulator.

4. The handheld sensor device of claim 3, wherein the phase accumulator comprises:

an N-bit phase register controlled by a clock signal comprising a clock frequency; and

an N-bit adder comprising;

a first input for a frequency control word from a microprocessor; and

a second input for feedback from the N-bit phase register,

wherein the contents of the N-bit phase register increase by the value of the frequency control word at the end of a cycle of the clock signal.

5. The handheld sensor device of claim 4, wherein a frequency of the waveform is selectively controlled by the frequency control word.

6. The handheld sensor device of claim 5, where the frequency of the waveform and a frequency resolution of the waveform are further based on the clock frequency and the N number of bits.

7. The handheld device of claim 3, wherein the DDFS further comprises:

a memory configured to receive an output of the phase accumulator;

a digital-to-analog converter configured to receive an output of the memory; and

an low-pass filter configured to remove harmonic distortion from an output of the digital-to-analog converter.

8. The handheld sensor device of claim 1, wherein the electrochemical technique is selected from the group comprising square wave voltammetry, cyclic voltammetry, linear sweep voltammetry, differential-pulse voltammetry, and normal-pulse voltammetry.

9. The handheld sensor device of claim 1, wherein the function generator comprises:

a first Schmitt circuit configured to generate a square wave;

a second Schmitt circuit configured to generate a triangle wave; and

a summing amplifier circuit configured to combine the square wave and the triangle wave.

10. The handheld sensor device of claim 9, wherein at least one of the first Schmitt circuit and the second Schmitt circuit comprises a constant current source.

11. The handheld sensor device of claim 1, wherein the current amplifier comprises an electrically conductive guard configured to reduce a portion of the current measured by the current amplifier that is attributable to a leakage current through the reference electrode.

12. The handheld sensor device of claim 1, wherein the control amplifier is further configured to prevent the reference electrode from polarizing.

13. The handheld sensor device of claim 1, wherein the current amplifier comprises a voltage meter referenced to ground.

14. The handheld sensor device of claim 1, wherein the current amplifier comprises a potentiometer controlled by a microprocessor to selectively adjust the gain of the current amplifier.

15. The handheld sensor device of claim 1, wherein the potentiostat further comprises a lock-in amplifier comprising a phase sensitive detector configured to multiply a phase shifted reference signal by the current provided through the counter electrode and the working electrode, the lock-in amplifier configured to reduce the current'"'"'s noise.

16. A handheld sensor device of claim 1 with a single integrated electrochemical chip, the single integrated electrochemical chip comprising:

a microprocessor;

said function generator which is controlled by the microprocessor to selectively generate a waveform for use in an electrochemical technique; and

said potentiostat which is configured to generate and measure a current in a solution.

17. The handheld sensor device with an integrated electrochemical chip of claim 16, wherein the function generator comprises:

a first Schmitt circuit configured to generate a square wave;

a second Schmitt circuit configured to generate a triangle wave; and

a summing amplifier circuit configured to combine the square wave and the triangle wave.

18. The handheld sensor device with an integrated electrochemical chip of claim 17, wherein at least one of the first Schmitt circuit and the second Schmitt circuit comprises a constant current source.