Cartridge and sensor-dispensing instrument

• US 8,609,037 B2
• Filed: 03/08/2012
• Issued: 12/17/2013
• Est. Priority Date: 06/24/2004
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Kheiri, Mohammad A., Purcell, D. Glenn
• Primary Examiner(s): MERKLING, SALLY ANNE
• Application Number:
  US13/415,695
• Publication Number:
  US 20120171757A1
• Time in Patent Office: 649 Days
• Field of Search: 422/58, 422/61, 422/82.01, 422/401, 422/102, 204/400, 414/796.8
• US Class Current: 422/401
• CPC Class Codes: B01L 3/523 with means for closing or opening
• CPC Class Codes: B01L 3/527 for a plurality of reagents
• CPC Class Codes: G01N 33/48 Biological material, e.g. blood, urine G01N33/02, G01N33/26, G01N33/44, G01N33/46 take precedence; Haemocytometers counting blood corpuscules distributed over a surface by scanning the surface G06M11/02
• CPC Class Codes: G01N 33/48757 Test elements dispensed from a stack
• CPC Class Codes: Y10T 436/193333 In aqueous solution

Abstract

A disposable cartridge adapted to be used with a sensor-dispensing instrument comprises a housing, test sensors, a mechanical mechanism and moveable seals. The housing forms at least one opening therethrough. The test sensors are stacked in the housing. The test sensors are adapted to assist in testing at least one analyte. The mechanical mechanism is adapted to urge the test sensors in a first direction. One of the test sensors is positioned for ejection from the cartridge. The moveable seals is adapted to be in a closed position that seals the at least one opening so as to provide a substantially moisture-proof and a substantially air-tight cartridge, and one of the moveable seals is adapted to be in an open position that allows one of the test sensors to be moved therethrough.

Claims

1. A cartridge, comprising:

a housing forming at least one opening therethrough;

a plurality of test sensors being stacked in the housing;

a mechanical mechanism configured to urge the plurality of test sensors in a first direction; and

a first pivotal seal including a body, a first protrusion, and a second protrusion, the first pivotal seal being configured to pivot about an axis of the body such that the first protrusion deforms and the first pivotal seal moves from a closed position to an open position, thereby permitting at least one of the test sensors to proceed towards an exterior of the housing, the first pivotal seal being biased in the closed position such that the second protrusion aids in sealing a first one of the at least one opening.

2. The cartridge of claim 1, wherein the second protrusion of the first pivotal seal physically contacts a bottom surface of the at least one of the test sensors and a portion of the housing physically contacts a top surface of the at least one of the test sensors in response to the at least one of the test sensors proceeding towards the exterior of the housing, the portion of the housing being directly across from the second protrusion of the first pivotal seal.

3. The cartridge of claim 1, wherein the first pivotal seal is configured to exert a force on the housing in response to the first pivotal seal being in the closed position.

4. The cartridge of claim 1, wherein the first pivotal seal is made from a flexible material with a certain degree of memory such that the first pivotal seal is configured to return to the closed position in response to the at least one of the test sensors being removed from the cartridge.

5. The cartridge of claim 1, further comprising a second pivotal seal that is separate and distinct from the first pivotal seal, the second pivotal seal being biased in a closed position to seal a second one of the at least one opening.

6. The cartridge of claim 5, wherein the second pivotal seal is configured to open inward towards an interior of the housing and the first pivotal seal is configured to open outward towards the exterior of the housing.

7. The cartridge of claim 5, wherein the first pivotal seal and the second pivotal seal are both proximate the exterior of the housing.

8. The cartridge of claim 5, further comprising a removable cap configured to seal the second one of the at least one opening prior to the cartridge being inserted into a sensor-dispensing instrument.

9. The cartridge of claim 5, further comprising a rupturable cover configured to seal the second one of the at least one opening, the rupturable cover being configured to be punctured by a portion of a sensor-dispensing instrument.

10. The cartridge of claim 9, in combination with a sensor-dispensing instrument, the sensor-dispensing instrument including a slider that is configured to:

(i) puncture the rupturable cover, (ii) enter the second one of the at least one opening, and (iii) engage at least one of the test sensors stored in the housing.

11. The cartridge of claim 10, in combination with a sensor-dispensing instrument, wherein the slider is configured to substantially seal the second one of the at least one opening.

12. The cartridge of claim 1, wherein at least one of the edges of at least one of the test sensors contacts an internal surface of the housing during storage of the test sensors therein.

13. The cartridge of claim 1, wherein there is no separate and distinct structure between at least one of the edges of at least one of the test sensors and an internal surface of the housing during storage.

14. The cartridge of claim 1, wherein the first pivotal seal is substantially enclosed within the housing.

15. The cartridge of claim 1, wherein the housing forms exactly two openings.

26. The cartridge of claim 1, wherein the second protrusion extends from the body in a second direction and wherein the first protrusion extends from the second protrusion in a third direction distinct from the second direction, and wherein the first pivotal seal is a unitary member.

16. A sensor-dispensing instrument, comprising:

a cartridge comprising;

a cartridge housing having a first opening and a second opening;

a plurality of test sensors being stacked in the cartridge housing;

a mechanical mechanism being configured to urge test sensors in a first direction;

a pivotal seal configured to seal the first opening, the pivotal seal including a body, a first protrusion, and a second protrusion, the pivotal seal being configured to pivot about an axis of the body such that the first protrusion deforms and the pivotal seal moves from a closed position to an open position, thereby permitting at least one of the test sensors to proceed towards an exterior of the cartridge housing, the pivotal seal being a unitary member; and

a cover configured to seal the second opening; and

an outer-instrument housing forming a dispensing outlet and being adapted to receive the cartridge.

17. The instrument of claim 16, wherein the cover is a removable cover that is removed prior to the cartridge being received in the outer-instrument housing, thereby exposing the second opening.

18. The instrument of claim 17, further comprising a pusher assembly, in response to the cartridge being received in the outer-instrument housing, during movement of the pusher assembly from a first position towards a second position, a portion of the pusher assembly is configured to enter the second opening of the cartridge.

19. The instrument of claim 18, wherein the portion of the pusher assembly is configured to substantially seal the second opening in response to the pusher assembly being in the second position.

20. The instrument of claim 16, wherein the cover is a rupturable cover.

21. The instrument of claim 20, further comprising a pusher assembly, in response to the cartridge being received in the outer-instrument housing, during movement of the pusher assembly from a first position towards a second position, the pusher assembly is configured to (i) puncture the rupturable cover, (ii) enter the second opening of the cartridge, (iii) engage at least one of the test sensors stored in the cartridge housing, and (iv) substantially seal the second opening.

22. The instrument of claim 16, wherein the second protrusion of the pivotal seal physically contacts a bottom surface of the at least one of the test sensors and a portion of the cartridge housing physically contacts a top surface of the at least one of the test sensors in response to the at least one of the test sensors proceeding towards the exterior of the cartridge housing, the portion of the cartridge housing being directly across from the second protrusion the pivotal seal.

23. The instrument of claim 16, wherein the pivotal seal is configured to exert a force on the cartridge housing in response to the pivotal seal being in the closed position.

24. The instrument of claim 16, wherein the pivotal seal is made from a flexible material with a certain degree of memory such that the pivotal seal is configured to return to the closed position in response to the at least one of the test sensors being removed from the instrument.

25. The instrument of claim 16, wherein the second protrusion extends from the body in a second direction and wherein the first protrusion extends from the second protrusion in a third direction distinct from the second direction.