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Multiplanar lateral flow assay with sample compressor

  • US 8,609,433 B2
  • Filed: 12/02/2010
  • Issued: 12/17/2013
  • Est. Priority Date: 12/04/2009
  • Status: Active Grant
First Claim
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1. A lateral flow device for detecting an analyte in a sample comprising:

  • a sample compressor comprising a pad;

    a sample collector comprising a sample collection portion for collection of the sample;

    a lateral flow chromatographic test strip comprising a sample application zone and a test zone laterally downstream from the sample application zone;

    a conjugate comprising a first binding partner for the analyte and a label;

    a second binding partner for the analyte;

    a first control binding partner located on the pad of the sample compressor; and

    the lateral flow chromatographic test strip further comprising a control zone comprising a second control binding partner immobilized in the control zone, wherein the first control binding partner is a binding partner for the second control binding partnerwherein the sample compressor, the sample collector, and the lateral flow chromatographic test strip form a vertical stack to apply the sample to the lateral flow chromatographic test strip by compression; and

    wherein the sample collector is located between the sample compressor and the lateral flow chromatographic test strip in the vertical stack.

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