Method and apparatus for guiding an instrument to a target in the lung

• US 8,611,983 B2
• Filed: 01/18/2006
• Issued: 12/17/2013
• Est. Priority Date: 01/18/2005
• Status: Active Grant

• Current Assignee: Philips Electronics Limited (Koninklijke Philips N.V.)
• Original Assignee: Philips Electronics Limited (Koninklijke Philips N.V.)
• Inventors: Glossop, Neil David
• Primary Examiner(s): Jung, Unsu
• Assistant Examiner(s): COOK, CHRISTOPHER L
• Application Number:
  US11/333,363
• Publication Number:
  US 20060184016A1
• Time in Patent Office: 2,890 Days
• Field of Search: 600/424, 600/426, 600/427, 600/428, 600/414
• US Class Current: 600/424
• CPC Class Codes: A61B 1/2676 Bronchoscopes
• CPC Class Codes: A61B 2017/0034 adapted to be inserted through a working channel of an endoscope
• CPC Class Codes: A61B 2017/00694 with means correcting for movement of or for synchronisation with the body
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for
• CPC Class Codes: A61M 2025/09191 made of twisted wires
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0113 Mechanical advancing means, e.g. catheter dispensers
• CPC Class Codes: A61M 25/0133 Tip steering devices
• CPC Class Codes: A61M 25/0136 Handles therefor

Abstract

The invention provides methods and apparatus for navigating a medical instrument to a target in the lung. In one embodiment, the invention includes inserting a bronchoscope into the lung, inserting a catheter into the lung through the working channel of the bronchoscope, inserting a tracked navigation instrument wire into the lung through the catheter, navigating the tracked navigation instrument through the lung to the target, advancing the catheter over the tracked navigation instrument to the target, removing the tracked navigation instrument from the catheter, and inserting a medical instrument into the catheter, thus bringing the medical instrument in proximity to the target.

Claims

1. An apparatus for utilizing an image of a lung of a patient and a target, the apparatus comprising:

a tracking device for obtaining coordinates of a plurality of positions of each of a plurality of first and second elements, each element providing coordinates of its position;

a tracked navigation instrument having one or more of the plurality of first elements thereon for insertion into the lung of the patient to produce accuracy coordinates of the positions of the one or more first elements when the tracked navigation instrument touches one or more known locations or fiducials on the patient, the accuracy coordinates verify accuracy of the image;

a motion compensation device having one or more of the plurality of second elements thereon for insertion into the tracked navigation instrument;

a computing device for mitigating an effect of patient movement on the image by

producing an initial alignment of coordinates of the image with the accuracy coordinates,

maintaining the alignment of the coordinates of the image with the coordinates of the positions of the second elements, and

showing on the image the tracked navigation instrument as it is advanced to the target and the motion compensation device as it is advanced over the tracked navigation instrument to the target.

2. The apparatus of claim 1, the tracking device comprising an electromagnetic tracking device.

3. The apparatus of claim 1, wherein the motion compensation device is selected from a dynamic referencing device, a respiratory gating device, a spirometer, a breath temperature sensor, an oxygen sensor, a carbon dioxide sensor, a signal from a respirator, an extensometer, an electrocardiograph, and a cardiac gating device and wherein the motion compensation device is configured to provide the coordinates of the positions of the first and second elements to adjust registration of a patient'"'"'s anatomy including the lung and improve accuracy of the displayed tracked navigation instrument.

4. The apparatus of claim 3, wherein the coordinates of the positions of the second elements are used to compensate for motion of the patient.

5. The apparatus of claim 1, wherein the tracked navigation instrument has a bent tip and is configured to be navigated to the target by manipulating the bent tip to point into a passageway of the lung leading to the target, while a position of the bent tip in the lung as indicated by the coordinates is displayed.

6. The apparatus of claim 1, wherein the tracked navigation instrument is selected from a guidewire, a catheter, a needle, a biopsy device, a brush, a laser device, a grasping device, an irrigation device, a radio frequency ablation device, and an ultrasound probe.

7. The apparatus of claim 1, further comprising a medical instrument selected from a catheter, a needle, a biopsy device, a brush, a laser device, a grasping device, an irrigation device, a radio frequency ablation device, and an ultrasound probe.

8. The apparatus of claim 7, wherein the medical instrument is configured to be inserted into the body of the patient.

9. The apparatus of claim 1, wherein the tracked navigation instrument is inserted through a lumen, the lumen is sized to slidably constrain the tracked navigation instrument to prevent the tracked navigation instrument from buckling while sliding within the lumen.

10. A method for utilizing an image of a lung of a patient and a target, the method comprising acts of:

registering anatomy of the patient by

inserting a tracked navigation instrument having one or more first elements thereon into the lung of the patient to produce accuracy coordinates of the positions of the one or more first elements when the tracked navigation instrument touches one or more known locations or fiducials on the patient, the accuracy coordinates verify accuracy of the image, each first element providing coordinates of its position, and

sampling by a tracking device the one or more first elements to obtain the coordinates of a plurality of positions of the one or more first elements;

maintaining registration of the anatomy of the patient by

inserting a motion compensation device having one or more second elements thereon into the tracked navigation instrument, and

sampling by the tracking device the one or more second elements to obtain the coordinates of a plurality of positions of the one or more second elements; and

a computing device mitigating an effect of patient movement on the image by

producing an initial alignment of coordinates of the image with the accuracy coordinates,

maintaining the alignment of the coordinates of the image with the coordinates of the positions of the second elements, and

displaying on the image the tracked navigation instrument and the motion compensation device advancing over the tracked navigation instrument to the target, after the tracked navigation instrument reaches the target.

11. The method of claim 10, wherein the tracking device comprises an electromagnetic tracking device.

12. The method of claim 10, wherein the tracked navigation instrument is inserted through a lumen comprising a bronchoscope.

13. The method of claim 10, wherein the motion compensation device is selected from one of:

a dynamic referencing device, a respiratory gating device, a spirometer, a breath temperature sensor, an oxygen sensor, a carbon dioxide sensor, a signal from a respirator, an extensometer, an electrocardiograph, or a cardiac gating device and wherein the motion compensation device is configured to provide the coordinates of the positions of the elements to adjust registration of a patients anatomy including the lung and improve accuracy of the displayed position of the tracked navigation instrument.

14. The method of claim 10, further comprising an act of:

displaying the position of the tracked navigation instrument in the lung on the display device,

wherein coordinates of the positions of the elements compensate for motion of the patient while displaying the position of the tracked navigation instrument in the lung.

15. The method of claim 10, wherein the tracked navigation instrument includes a bent tip.

16. The method of claim 15, comprising acts of:

manipulating the bent tip to point into a passageway of the lung leading to the target while viewing a position of the bent tip on the display of the tracked navigation instrument in the lung; and

advancing the tracked navigation instrument into the passageway towards the target.

17. The method of claim 10, wherein the target is selected from a lesion, a mass, and a tumor.

18. The method of claim 10, wherein the tracked navigation instrument is selected from a guidewire, a catheter, a needle, a biopsy device, a brush, a laser device, a grasping device, an irrigation device, a radio frequency ablation device, and an ultrasound probe.

19. The method of claim 10, further comprising an act of guiding a medical instrument to the target in the lung of the patient, the medical instrument is selected from a catheter, a needle, a biopsy device, a brush, a laser device, a grasping device, an irrigation device, a radio frequency ablation device, and an ultrasound probe.

20. The method of claim 19, wherein the medical instrument is inserted in to an interior of the patient.

21. A method for guiding a medical instrument to a target in a lung of a patient utilizing an image of the lung and the target, the method comprising acts of:

generating a registration transformation of a first coordinate system of at least one image of the lung and a second coordinate system of position information regarding the lung by

inserting a tracked navigation instrument having one or more first elements thereon into the lung to produce accuracy coordinates of the positions of the one or more first elements when the tracked navigation instrument touches one or more known locations or fiducials on the patient, the accuracy coordinates verify accuracy of the image, and

sampling by a tracking device the one or more first elements to obtain the coordinates of a plurality of positions of the one or more first elements;

generating by a computing device a display of the tracked navigation instrument in the lung using the at least one image of the lung and the registration transformation including the accuracy coordinates;

navigating the tracked navigation instrument to the target using the display of the tracked navigation instrument in the lung;

mitigating an effect of patient movement on the display by re-generating the registration transformation of the second coordinate system by inserting into the lung a motion compensation device having one or more second elements readable by the tracking device to obtain coordinates of a plurality of positions of the one or more second elements;

re-generating, by the computing device, the display using the at least one image of the lung and the re-generated registration transformation;

advancing a catheter over the tracked navigation instrument to the target after the tracked navigation instrument reaches the target; and

navigating the medical instrument to the target through the catheter using the re-generated display.