Systems, methods and computer program products for heart monitoring

• US 8,611,990 B2
• Filed: 02/25/2011
• Issued: 12/17/2013
• Est. Priority Date: 03/05/2004
• Status: Active Grant

• Current Assignee: Complete Medical Solutions LLC
• Original Assignee: Lifesciences Solutions LLC
• Inventors: Richardson, Charles L.
• Primary Examiner(s): MALAMUD, DEBORAH LESLIE
• Application Number:
  US13/035,259
• Publication Number:
  US 20110152705A1
• Time in Patent Office: 1,026 Days
• Field of Search: 600508-510, 600/513, 600/523, 600/546, 607 1- 2, 607/60, 607/115
• US Class Current: 600/509
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/413 Monitoring transplanted tissue or organ, e.g. for possible rejection reactions after a transplant
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

The present invention provides systems, methods and computer program products for monitoring a heart. According to one embodiment, the system includes an implantable registering unit. The registering unit comprises a first controller structured to register an electrical signal from the heart. The system includes a second controller in operable communication with the first controller. The second controller comprises a data repository structured to receive data corresponding to the registered electrical signal and being structured to store the data. The data repository stores data corresponding to a baseline electrical signal of the heart. The second controller is structured to receive the data from the first controller corresponding to the registered electrical signal and to compare the registered electrical signal to the baseline electrical signal to determine whether the heart is functioning properly.

Claims

1. A system for monitoring a patient'"'"'s heart, comprising:

a registering unit comprising a first controller in electrical communication with the patient'"'"'s heart, said first controller being configured to register an electrical signal emitted by the patient'"'"'s heart; and

a second controller in operable communication with said first controller, said second controller being configured to receive data from said first controller corresponding to the registered electrical signal;

to generate a registered template comprising a digital graphical representation of an intracardiac electrogram for the registered electrical signal; and

to compare the registered template to a baseline template comprising a digital graphical representation of an intracardiac electrogram for a baseline electrical signal emitted by the patient'"'"'s heart to determine whether the patient'"'"'s heart is functioning properly, wherein the second controller is adapted to compare the baseline template and the registered template through a wavelet transformation in which the templates are transformed to create one or more wavelets in the form of corresponding fragments of the templates, the second controller being adapted to compare one or more registered wavelets to one or more corresponding baseline wavelets to determine whether the patient'"'"'s heart is functioning properly.

2. The system of claim 1, wherein said registering unit further comprises a transmitter in operable communication with said second controller.

3. The system of claim 1, further comprising a relay unit independent of said first controller and said second controller and configured to communicate with said first controller and said second controller, said relay unit being configured to receive data from said first controller corresponding to the registered electrical signal and to transmit the received data to said second controller.

4. The system of claim 3, wherein the relay unit is configured to wirelessly communicate with said registering unit.

5. The system of claim 1, wherein said second controller is located remotely from said registering unit.

6. The system of claim 1, wherein said second controller includes a data repository for storing data corresponding to the registered template and data corresponding to the baseline template of the patient'"'"'s heart.

7. The system of claim 1, further comprising a plurality of electrodes in electrical communication with said registering unit and configured to be coupled directly to the heart.

8. The system of claim 1, wherein said second controller is configured to determine whether a predetermined critical match-percent threshold has been exceeded based on a comparison of the registered template and the baseline template.

9. The system of claim 8, wherein the critical match-percent threshold comprises at least 70% correlation between the registered template and the baseline template, wherein a critical-match percent threshold less than 70% indicates that the heart is not functioning properly.

10. The system of claim 8, wherein the critical match-percent threshold comprises at least 80% correlation between the registered template and the baseline template, wherein a critical-match percent threshold less than 80% indicates that the heart is not functioning properly.

11. The system of claim 8, wherein the critical match-percent threshold comprises at least 90% correlation between the registered template and the baseline template, wherein a critical-match percent threshold less than 90% indicates that the heart is not functioning properly.

12. The system of claim 1, wherein said second controller is configured to measure the area between the registered template and the baseline template to determine whether the patient'"'"'s heart is functioning properly.

13. The system of claim 1, wherein said second controller is configured to identify a plurality of comparison points for the registered template and to identify a plurality of comparison points for the baseline template, each of the plurality of comparison points for the baseline template corresponding to one of the comparison points for the registered template, and wherein said second controller is configured to measure differences between each of the corresponding plurality of comparison points for the registered template and the baseline template to determine whether the patient'"'"'s heart is functioning properly.

14. The system according to claim 1, wherein said registering unit further comprises a housing of biologically inert material for housing said first controller.

15. The system of claim 1, wherein said second controller is configured to calculate a quantifiable difference between the registered template and the baseline template based on the comparison between the templates in order to determine whether the patient'"'"'s heart is functioning properly.

16. The system of claim 1, wherein said second controller is configured to compare the registered template to the baseline template following a heart transplant in order to determine whether the patient'"'"'s transplanted heart is being rejected.

17. The system of claim 1, wherein the second controller determines a percent wavelet match between the registered wavelets and baseline wavelets to determine whether the patient'"'"'s heart is functioning properly.

18. The system of claim 1, wherein the second controller performs one of an area of discrepancy determination and a comparison of corresponding points determination of the registered wavelets and baseline wavelets to determine whether the patient'"'"'s heart is functioning properly.

19. The system of claim 1, wherein the wavelet transformation comprises identifying frequency and scale components of the signals represented graphically by the templates simultaneously with its location in time, the transformation further comprising scale analysis via creation of mathematical structures that provide varying time, frequency, and amplitude slices for comparison to determine whether the patient'"'"'s heart is functioning properly.