Method and assembly for determining the temperature of a test sensor

• US 8,614,097 B2
• Filed: 11/05/2012
• Issued: 12/24/2013
• Est. Priority Date: 10/15/2007
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Blais, Jeffrey D., Sun, Steve, Harrison, Bern, Parasnis, Narasinha C., Peteu, Serban F., Nguyen, Tony, Ripley, Paul, Wang, Xin, Gofman, Igor
• Primary Examiner(s): Wallenhorst, Maureen
• Application Number:
  US13/669,034
• Publication Number:
  US 20130061663A1
• Time in Patent Office: 414 Days
• Field of Search: 436/63, 436/95, 436/147, 436/164, 422/82.12, 435/14, 374/120, 374/121, 374/131, 374/141, 374/142, 600/474, 600/549
• US Class Current: 436/147
• CPC Class Codes: A61B 2560/0242 adapted to measure environmental factors, e.g. temperature, pollution
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: G01N 21/78 producing a change of colour
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771

Abstract

An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction with an analyte in the sample. The assembly also includes a meter having a port or opening configured to receive the test sensor; a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and a temperature-measuring system configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening. The meter determines a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature.

Claims

1. A meter for determining an analyte concentration in a fluid sample received on a test sensor, the test sensor comprising a fluid-receiving area for receiving the fluid sample, the fluid-receiving area containing a reagent that produces a measurable reaction with an analyte in the sample, the test sensor having a test-sensor temperature and the reagent having a reagent temperature, the meter comprising:

an opening configured to receive the test sensor such that a region of the test sensor is disposed inside the meter and the fluid-receiving area of the test sensor is disposed outside the meter;

a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and

a temperature-measuring system including a temperature sensor configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening, the temperature sensor measuring the region of the test sensor disposed inside the meter while the fluid-receiving area is disposed outside the meter,

wherein the meter determines a concentration of the analyte in the sample using the measurement of the reaction and the measurement of the test-sensor temperature.

2. The meter of claim 1, wherein the opening extends from a first end proximate to an exterior surface of the meter to a second end in an interior of the meter, and the temperature sensor is positioned near the second end to minimize heat transfer to the region of the test sensor being measured by the temperature sensor.

3. The meter of claim 1, wherein the temperature sensor receives a temperature-related signal from the region of the test sensor being measured, and the temperature sensor and the region of the test sensor are separated by a space, the space forming an insulating air pocket around the region to minimize heat transfer to the region.

4. The meter of claim 1, further comprising at least one point contact to contact the test sensor while minimizing heat transfer from the meter to the test sensor.

5. The meter of claim 1, wherein the temperature sensor is disposed inside the meter and configured to measure the region of the test sensor disposed inside the meter.

6. A method for determining an analyte concentration in a sample of body fluid, comprising the steps of:

placing a test sensor into an opening of a meter, the opening being configured to receive the test sensor, the test sensor comprising a fluid-receiving area for receiving a sample of body fluid, the fluid-receiving area containing a reagent that produces a measurable reaction with an analyte in the sample, the test sensor having a test-sensor temperature and the reagent having a reagent temperature;

estimating a measurement of the test-sensor temperature when the test sensor is received into the opening by measuring, with a temperature sensor, a region of the test-sensor when the region is disposed inside the meter and the fluid-receiving area of the test sensor is disposed outside the meter;

measuring the reaction between the reagent and the analyte in the sample; and

determining a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature.

7. The method of claim 6, wherein the opening extends from a first end proximate to an exterior surface of the meter to a second end in an interior of the meter, and the act of placing a test sensor into an opening comprises positioning the temperature sensor near the second end to minimize heat transfer to the region of the test sensor being measured by the temperature sensor.

8. The method of claim 6, wherein the act of determining a measurement of the test-sensor temperature comprises receiving, via the temperature sensor, a temperature-related signal from the region of the test sensor being measured, and the act of placing a test sensor into an opening comprises providing a space between the temperature sensor and the region of the test sensor, the space forming an insulating air pocket around the region to minimize heat transfer to the region.

9. The method of claim 6, wherein any contact between the meter and the test sensor is a point contact to minimize heat transfer from the meter to the test sensor.

10. The method of claim 6, wherein the temperature sensor is disposed inside the meter and configured to measure the region of the test sensor disposed inside the meter.

11. The method of claim 6, wherein the test-sensor temperature and the reagent temperature are at about an ambient temperature.