Analyte sensor

• US 8,615,282 B2
• Filed: 02/22/2006
• Issued: 12/24/2013
• Est. Priority Date: 07/13/2004
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark, Masterson, Steve, Saint, Sean, Simpson, Peter, Wightlin, Matthew D., Petisce, James R., Pryor, Jack, Swanson, Vance, Nolting, John
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US11/360,262
• Publication Number:
  US 20060142651A1
• Time in Patent Office: 2,862 Days
• Field of Search: 600/365, 600345-366, 600/309
• US Class Current: 600/345
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61B 2560/028 Arrangements to prevent overuse, e.g. by counting the number of uses
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/1451 for interstitial fluid
• CPC Class Codes: A61B 5/14517 for sweat
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/6832 using adhesives A61B5/259 takes precedence
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61B 5/6849 in combination with a needle set
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61L 2/12 Microwaves
• CPC Class Codes: A61L 2/206 : Ethylene oxide
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10T 29/49004 : including measuring or testing of device or component part

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1. A device for use in measuring an analyte in a host, the device comprising:

a sensor operably connected to sensor electronics configured for measuring an analyte in a host;

at least one electrical contact configured to operably connect the sensor to the sensor electronics;

a housing adapted for placement adjacent to the host'"'"'s skin; and

a sealing member configured to at least partially surround the at least one electrical contact, wherein the sealing member is configured to seal the at least one electrical contact from moisture by a compression force between the sealing member and the at least one electrical contact when the sensor is operably connected to the sensor electronics, wherein the sealing member is held on the housing by at least one protrusion configured to substantially mate with at least one depression.

2. The device of claim 1, wherein the sealing member comprises a material having a durometer hardness of from about 5 Shore A to about 80 Shore A.

3. The device of claim 1, further comprising a sealant adjacent to the sealing member.

4. The device of claim 1, wherein the sealing member comprises a material selected from the group consisting of silicone, silicone/polyurethane hybrid, polyurethane, polysulfide, and mixtures thereof.

5. The device of claim 1, wherein the sealing member is self-lubricating.

6. The device of claim 1, wherein the sealing member comprises a sealant.

7. The device of claim 1, wherein the sealing member comprises at least one raised portion configured to form an interference fit between the sealing member and the sensor electronics when the sensor is operably connected to the sensor electronics.

8. The device of claim 7, wherein the at least one raised portion comprises a plurality of raised portions.

9. The device of claim 7, wherein the at least one raised portion is configured to surround each of the at least one electrical contacts when the sensor is operably connected to the sensor electronics.

10. The device of claim 1, wherein the sensor electronics comprise at least one electrical contact configured to physically connect with the at least one electrical contact when the sensor is operably connected to the sensor electronics.

11. A device for use in measuring an analyte in a host, the device comprising:

a sensor operably connected to sensor electronics configured for measuring an analyte in a host;

at least one electrical contact configured to operably connect the sensor to the sensor electronics;

a housing adapted for placement adjacent to the host'"'"'s skin;

a sealing member configured to at least partially surround the at least one electrical contact, wherein the sealing member is configured to seal the at least one electrical contact from moisture by a compression force between the sealing member and the at least one electrical contact when the sensor is operably connected to the sensor electronics; and

a guide tube configured to maintain an opening in the sealing member prior to sensor insertion into the host.

12. The device of claim 11, further comprising a lubricant between the sealing member and the guide tube.