Methods and systems for detecting a bioactive agent effect

• US 8,615,407 B2
• Filed: 09/15/2008
• Issued: 12/24/2013
• Est. Priority Date: 04/24/2008
• Status: Active Grant

• Current Assignee: Harvest Bio LLC
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Ishikawa, Muriel Y., Leuthardt, Eric C., Levien, Royce A., Lord, Robert W., Malamud, Mark A., Sweeney, Elizabeth A., Wood, Lowell L. Jr., Wood, Victoria Y. H.
• Primary Examiner(s): NGUYEN, HIEP VAN
• Application Number:
  US12/283,742
• Publication Number:
  US 20090271121A1
• Time in Patent Office: 1,926 Days
• Field of Search: 705/2
• US Class Current: 705/2
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16H 70/40 relating to drugs, e.g. their side effects or intended usage

Abstract

Methods, computer program products, and systems are described that include accepting at least one indication of bioactive agent use by an individual and/or presenting an indication of an artificial sensory experience programmed to detect at least one effect of the bioactive agent at least partly based on the at least one indication of the bioactive agent.

Claims

1. A system, comprising:

an accepter module configured to accept at least one indication of bioactive agent use by an individual;

a presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent; and

an algorithm utilizer module configured to utilize an algorithm configured to detect at least one effect of the bioactive agent accepted by the accepter module upon the individual in the virtual world presented by the presenter module,

wherein at least one of the accepter module, presenter module, or algorithm module is at least partially implemented in computing hardware.

2. The system of claim 1, wherein the accepter module configured to accept at least one indication of bioactive agent use by an individual comprises:

a bioactive agent accepter module configured to accept an identification of at least one bioactive agent prescribed for the individual.

3. The system of claim 2, wherein the bioactive agent accepter module configured to accept an identification of at least one bioactive agent prescribed for the individual comprises:

a medication accepter module configured to accept an identification of at least one of an anti-depressant, an anxiolytic medication, a pain medication, a behavior modifying medication, a weight adjustment drug, an anti-Alzheimer'"'"'s medication, or an anti-stroke medication as the at least one bioactive agent.

4. The system of claim 1, wherein the accepter module configured to accept at least one indication of bioactive agent use by an individual comprises:

a substance abuse accepter module configured to accept an indication of a substance subject to abuse used by the individual.

5. The system of claim 1, wherein the accepter module configured to accept at least one indication of bioactive agent use by an individual comprises:

a nutraceutical use accepter module configured to accept an indication of nutraceutical use by the individual.

6. The system of claim 1, wherein the accepter module configured to accept at least one indication of bioactive agent use by an individual comprises:

a participant accepter module configured to accept an indication of bioactive agent use by at least one of a computer game participant, a social networking tool user, a virtual world participant, an online student, an online medical information user, or an online shopper.

7. The system of claim 1, wherein the accepter module configured to accept at least one indication of bioactive agent use by an individual comprises:

an individual accepter module configured to accept an indication of bioactive agent use by an individual not previously associated with an artificial sensory experience.

8. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a continuous monitoring presenter module configured to present an indication of an artificial sensory experience programmed to continuously monitor at least one effect of at least one bioactive agent.

9. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a time interval presenter module configured to present an indication of an artificial sensory experience programmed to monitor at least one effect of at least one bioactive agent during at least one specified time interval.

10. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a discrete time monitoring presenter module configured to present an indication of an artificial sensory experience programmed to monitor at least one effect of at least one bioactive agent at a discrete time.

11. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a near real time monitorer module configured to monitor at least one effect of the bioactive agent in near real time.

12. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a physiologic characteristic presenter module configured to present an indication of an artificial sensory experience programmed to measure a physiologic characteristic of the individual.

13. The system of claim 12, wherein the physiologic characteristic presenter module configured to present an indication of an artificial sensory experience programmed to measure a physiologic characteristic of the individual comprises:

an administration monitorer module configured to monitor at least one of physical activity, body weight, body mass index number, heart rate, blood oxygen level, or blood pressure proximate to administration of the bioactive agent.

14. The system of claim 12, wherein the physiologic characteristic presenter module configured to present an indication of an artificial sensory experience programmed to measure a physiologic characteristic of the individual comprises:

a bioavailability monitorer module configured to monitor at least one of physical activity, body weight, body mass index number, heart rate, blood oxygen level, or blood pressure associated with bioavailability of the bioactive agent.

15. The system of claim 12, wherein the physiologic characteristic presenter module configured to present an indication of an artificial sensory experience programmed to measure a physiologic characteristic of the individual comprises:

a body monitorer module configured to monitor at least one of physical activity, body weight, body mass index number, heart rate, blood oxygen level, or blood pressure temporally associated with the bioactive agent.

16. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a neurophysiological activity monitorer module configured to monitor at least one neurophysiological activity.

17. The system of claim 1, wherein the algorithm utilizer module configured to utilize an algorithm configured for detecting the at least one effect of the bioactive agent accepted by the accepter module upon the individual in the virtual world presented by the presenter module comprises:

the algorithm utilizer module configured to select at least one algorithm configured for detecting at least one effect of the bioactive agent.

18. The system of claim 1, wherein the algorithm utilizer module configured to utilize an algorithm configured for detecting the at least one effect of the bioactive agent accepted by the accepter module upon the individual in the virtual world presented by the presenter module comprises:

a movement frequency algorithm utilizer module configured to utilize an algorithm configured to detect frequency of body movement.

19. The system of claim 1, wherein the algorithm utilizer module configured to utilize an algorithm configured for detecting the at least one effect of the bioactive agent accepted by the accepter module upon the individual in the virtual world presented by the presenter module comprises:

a startle state algorithm utilizer module configured to utilize an algorithm configured to detect startle state based on physiological signals.

20. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a behavior link presenter module configured to present an indication of an artificial sensory experience configured to link at least one of a predetermined behavior or a predetermined action to at least one effect of the bioactive agent.

21. The system of claim 1, wherein the presenter module configured to present an indication of a virtual world at least partly based on the at least one indication of the bioactive agent comprises:

a modification presenter module configured to present an indication of a modified combined bioactive agent and artificial sensory experience at least partially based on a modified at least one bioactive agent or artificial sensory experience.

22. The system of claim 21, wherein the modification presenter module configured to present an indication of a modified combined bioactive agent and artificial sensory experience at least partially based on a modified at least one bioactive agent or artificial sensory experience comprises:

an output device presenter module configured to present to at least one output device.

23. The system of claim 22, wherein the output device presenter module configured to present to at least one output device comprises:

a user interface presenter module configured to present to at least one user interface.

24. The system of claim 22, wherein the output device presenter module configured to present to at least one output device comprises:

a mobile device presenter module configured to present to at least one mobile device.

25. The system of claim 21, wherein the modification presenter module configured to present an indication of a modified combined bioactive agent and artificial sensory experience at least partially based on a modified at least one bioactive agent or artificial sensory experience comprises:

a third party presenter module configured to present to a third party.

26. The system of claim 25, wherein the third party presenter module configured to present to a third party comprises:

a health care provider presenter module configured to present to a health care provider.

27. The system of claim 25, wherein the third party presenter module configured to present to a third party comprises:

a selective presenter module configured to selectively present only to the individual.