Self-lubricating pharmaceutical syringe stoppers

• US 8,618,185 B2
• Filed: 10/01/2010
• Issued: 12/31/2013
• Est. Priority Date: 10/01/2009
• Status: Active Grant

• Current Assignee: Momentive Performance Materials Incorporated (Momentive Performance Materials Holdings LLC)
• Original Assignee: Momentive Performance Materials Incorporated (Momentive Performance Materials Holdings LLC)
• Inventors: Conzone, Samuel D., Rusinko, David M., Raman, Chandrashekar
• Primary Examiner(s): Seidleck, James J
• Assistant Examiner(s): Salamon, Peter A
• Application Number:
  US12/896,327
• Publication Number:
  US 20110082430A1
• Time in Patent Office: 1,187 Days
• Field of Search: None
• US Class Current: 522/75
• CPC Class Codes: A61M 2005/3131 specially adapted for improving sealing or sliding
• CPC Class Codes: A61M 5/31513 Piston constructions to improve sealing or sliding
• CPC Class Codes: C10M 169/04 Mixtures of base-materials and additives
• CPC Class Codes: C10M 2201/041 Carbon; Graphite; Carbon black
• CPC Class Codes: C10M 2201/061 Carbides; Hydrides; Nitrides
• CPC Class Codes: C10M 2205/20 Natural rubber; Natural resins
• CPC Class Codes: C10M 2205/203 used as base material
• CPC Class Codes: C10M 2213/062 Polytetrafluoroethylene [PTFE]
• CPC Class Codes: C10M 2229/025 used as base material
• CPC Class Codes: C10N 2030/06 Oiliness; Film-strength; Anti-wear; Resistance to extreme pressure
• CPC Class Codes: C10N 2040/50 Medical uses

Abstract

In one aspect, a self-lubricating component is provided for a pharmaceutical packaging assembly. The self-lubricating component comprises a polymer composition and an effective amount of a lubricating additive such as, for example, boron nitride. In another aspect, a pharmaceutical packaging assembly may be provided having a surface thereof coated with a lubricating composition comprising boron nitride. The pharmaceutical packaging composition may be, for example, a pre-filled syringe comprising a body (barrel) and a plunger assembly.

Claims

1. A self-lubricating component for a pharmaceutical packaging assembly comprising a polymer composition comprising an effective amount of boron nitride;

wherein the boron nitride is present in an amount of from about 3 to about 50% by weight of the polymer composition and wherein the component is in the form of a plunger, piston, diaphragm, or valve disc for medical equipment.

2. The component of claim 1, wherein the boron nitride is present in an amount of from about 3 to about 20% by weight of the polymer composition.

3. The component of claim 1, wherein the boron nitride is present in an amount of from about 5 to about 10% by weight of the polymer composition.