System and methods for processing analyte sensor data
First Claim
1. A system for calibrating a glucose sensor, the system comprising:
- a continuous glucose sensor configured to substantially continuously measure a glucose concentration in a host and provide sensor data associated therewith;
a reference glucose monitor configured to measure the host'"'"'s blood glucose concentration at a time point and provide reference data associated therewith; and
a processor module configured to form a plurality of matched pairs by matching sensor data to substantially time corresponding reference data, wherein the processor module is further configured to evaluate a congruence of respective sensor data and reference data within at least one matched pair of the plurality of matched data pairs and select at least one matched data pair of the plurality of matched data pairs based on the congruence evaluation for modification of a conversion function.
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Abstract
Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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Citations
9 Claims
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1. A system for calibrating a glucose sensor, the system comprising:
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a continuous glucose sensor configured to substantially continuously measure a glucose concentration in a host and provide sensor data associated therewith; a reference glucose monitor configured to measure the host'"'"'s blood glucose concentration at a time point and provide reference data associated therewith; and a processor module configured to form a plurality of matched pairs by matching sensor data to substantially time corresponding reference data, wherein the processor module is further configured to evaluate a congruence of respective sensor data and reference data within at least one matched pair of the plurality of matched data pairs and select at least one matched data pair of the plurality of matched data pairs based on the congruence evaluation for modification of a conversion function. - View Dependent Claims (2, 3, 4, 5)
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6. A method for calibrating a glucose sensor, the method comprising:
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receiving a data stream from an analyte sensor, the data stream comprising one or more sensor data points; receiving reference data from a reference analyte monitor, the reference data comprising one or more reference data points; using a processor module to match the one or more sensor data points to the one or more reference data points to form a plurality of matched pairs; using the processor module to evaluate a congruence of respective sensor data and reference data within at least one matched data pair of the plurality of matched pairs; and using the processor module to select at least one matched data pair of the plurality of matched data pairs based on the congruence evaluation for modification of a conversion function. - View Dependent Claims (7, 8, 9)
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Specification