Guidewire with two flexible end portions and method of accessing a branch vessel therewith

• US 8,622,934 B2
• Filed: 04/25/2011
• Issued: 01/07/2014
• Est. Priority Date: 04/25/2011
• Status: Active Grant

• Current Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Inventors: Muzslay, Heath, Johnson, Emilie, Haggard, Matthew
• Primary Examiner(s): NGUYEN, TUAN VAN
• Application Number:
  US13/093,631
• Publication Number:
  US 20120271397A1
• Time in Patent Office: 988 Days
• Field of Search: 606/194, 606/195, 606/198, 623/1.11, 623/1.12, 623/1.13, 623/1.23, 623/1.35
• US Class Current: 600/585
• CPC Class Codes: A61M 25/09 Guide wires

Abstract

A guidewire having flexible or floppy proximal and distal end portions is used for percutaneously accessing a branch vessel through a deployed prosthesis having at least one fenestration near an ostium of the branch vessel. The prosthesis is delivered and deployed via a first percutaneous access site. The guidewire extends over the outside surface of the deployed prosthesis and extends through the at least one fenestration. The flexible distal end portion is snared via a second percutaneous access site and is pulled in a direction towards the second percutaneous access site until the flexible proximal end of the guidewire is located adjacent to the branch vessel. A guide catheter is then advanced over the guidewire until it cannulates the branch vessel. The flexible proximal end of the guidewire may then be advanced into the branch vessel and used for delivery of a branch vessel prosthesis.

Claims

1. A method of percutaneously accessing a branch vessel through an at least partially deployed prosthesis having at least one fenestration positioned in the vicinity of an ostium of the branch vessel, the method comprising:

at least partially deploying the prosthesis through a first percutaneous access site such that the at least one fenestration is positioned in the vicinity of the ostium of the branch vessel, wherein a flexible distal end portion of a guidewire is disposed at least partially within a lumen of the prosthesis;

snaring the flexible distal end portion of the guidewire via a second percutaneous access site;

pulling the flexible distal end portion of the guidewire in a direction towards the second percutaneous access site until a flexible proximal end of the guidewire is located adjacent to the ostium of the branch vessel;

advancing a guide catheter over the guidewire until a distal end of the guide catheter is located within the fenestration and at least near the ostium of the branch vessel; and

advancing the flexible proximal end of the guidewire into the branch vessel.

2. The method of claim 1, wherein both the flexible distal end portion and the flexible proximal end portion are of greater flexibility than an elongate body of the guidewire.

3. The method of claim 2, wherein the flexible proximal and distal end portions are of the same construction and stiffness.

4. The method of claim 2, wherein the flexible proximal and distal end portions are of differing constructions and stiffnesses.

5. The method of claim 2, wherein the flexible proximal and distal end portions each include a tapered core wire and a helical coil that is attached to and extends about the tapered core wires.

6. The method of claim 1, wherein the branch artery emanates from the aorta.

7. The method of claim 1, wherein the flexible distal end portion of the guidewire is threaded through the at least one fenestration of the prosthesis such that the distal end of the guidewire extends from an outer surface of the prosthesis, through the at least one fenestration to the lumen of the prosthesis.

8. The method of claim 7, wherein the guidewire is preloaded in the location with at least a portion of the distal end in the lumen of the prosthesis.

9. The method of claim 1, wherein the first percutaneous access site is located in a direction of a first end of the prosthesis and the second percutaneous access site is located in a direction of a second end the prosthesis opposite the first end.

10. The method of claim 9, wherein the first percutaneous access site is through a femoral artery and the second percutaneous access site is through a brachial artery or a subclavian artery.

11. The method of claim 1, wherein a branch prosthesis is delivered into the branch vessel over the guidewire after the flexible proximal end of the guidewire is advanced into the branch vessel.

12. The method of claim 1, wherein a tube is preloaded in the prosthesis such that a distal end of the tube extends from an outer surface of the prosthesis, through the at least one fenestration, and into the lumen of the prosthesis, and wherein the step of at least partially deploying the prosthesis further comprises the steps of:

advancing the guidewire through the tube to position the flexible distal end portion of the guidewire at least partially within the lumen of the prosthesis; and

withdrawing the tube proximally through the first percutaneous access site, and leaving the flexible distal end portion of the guidewire disposed at least partially within the lumen of the prosthesis.

13. A method of percutaneously accessing a branch vessel through an at least partially deployed prosthesis having at least one fenestration positioned in the vicinity of an ostium of the branch vessel, the method comprising:

preloading a guidewire through the at least one fenestration of the prosthesis such that a flexible distal end portion of the guidewire is threaded through the at least one fenestration from an outer surface of the prosthesis and into a lumen of the prosthesis;

percutaneously introducing the prosthesis and the preloaded guidewire into the vasculature via a first access site;

at least partially deploying the prosthesis such that the at least one fenestration is positioned in the vicinity of the ostium of the branch vessel;

snaring the flexible distal end portion of the guidewire via a second percutaneous access site;

pulling the flexible distal end portion of the guidewire in a direction towards the second percutaneous access site until a flexible proximal end of the guidewire is located adjacent to the ostium of the branch vessel;

advancing a guide catheter over the guidewire until a distal end of the guide catheter is located within the fenestration and at least near the ostium of the branch vessel; and

advancing the flexible proximal end of the guidewire into the branch vessel.

14. The method of claim 13, wherein both the flexible distal end portion and the flexible proximal end portion are of greater flexibility than an elongate body of the guidewire.

15. The method of claim 13, wherein the first percutaneous access site is located in a direction of a first end of the prosthesis and the second percutaneous access site is located in a direction of a second end the prosthesis opposite the first end.

16. The method of claim 15, wherein the first percutaneous access site is through a femoral artery and the second percutaneous access site is through a brachial artery or a subclavian artery.

17. A method of percutaneously accessing a branch vessel through an at least partially deployed prosthesis having at least one fenestration is positioned in the vicinity of an ostium of the branch vessel, the method comprising the steps of:

preloading a tube through the at least one fenestration of the prosthesis such that a distal end portion of the tube is threaded through the at least one fenestration from an outer surface of the prosthesis and into a lumen of the prosthesis;

percutaneously introducing the prosthesis and the preloaded tube into the vasculature via a first access site;

at least partially deploying the prosthesis such that the at least one fenestration is positioned in the vicinity of the ostium of the branch vessel;

advancing a guidewire through the tube to position a flexible distal end portion of the guidewire at least partially within the lumen of the prosthesis;

withdrawing the tube proximally through the first percutaneous access site;

snaring the flexible distal end portion of the guidewire via a second percutaneous access site;

pulling the flexible distal end portion of the guidewire in a direction towards the second percutaneous access site until a flexible proximal end of the guidewire is located adjacent to the ostium of the branch vessel;

advancing a guide catheter over the guidewire until a distal end of the guide catheter is located within the fenestration and at least near the ostium of the branch vessel; and

advancing the flexible proximal end of the guidewire into the branch vessel.

18. The method of claim 17, wherein both the flexible distal end portion and the flexible proximal end portion are of greater flexibility than an elongate body of the guidewire.

19. The method of claim 17, wherein the first percutaneous access site is located in a direction of a first end of the prosthesis and the second percutaneous access site is located in a direction of a second end the prosthesis opposite the first end.

20. The method of claim 19, wherein the first percutaneous access site is through a femoral artery and the second percutaneous access site is through a brachial artery or a subclavian artery.