Permeable pressure sensitive adhesive

• US 8,624,078 B2
• Filed: 12/18/2009
• Issued: 01/07/2014
• Est. Priority Date: 12/18/2008
• Status: Active Grant

• Current Assignee: Coloplast A/S
• Original Assignee: Coloplast A/S
• Inventors: Buus, Hasse, Lykke, Mads, Kongebo, Tom Bjarke
• Primary Examiner(s): Brown, Michael A.
• Application Number:
  US13/140,192
• Publication Number:
  US 20110251542A1
• Time in Patent Office: 1,481 Days
• Field of Search: 602 41- 54, 524/556, 524/563, 604/344
• US Class Current: 602/54
• CPC Class Codes: A61L 15/585 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 24/043 Mixtures of macromolecular materials
• CPC Class Codes: A61L 2400/14 Adhesives for ostomy devices
• CPC Class Codes: C08K 5/0008 Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
• CPC Class Codes: C08L 23/08 Copolymers of ethene C08L23/16 takes precedence
• CPC Class Codes: C08L 23/0853 Vinylacetate
• CPC Class Codes: C08L 23/22 Copolymers of isobutene; Butyl rubber ; Homo- or copolymers of other iso-olefins
• CPC Class Codes: C08L 2666/06 Homopolymers or copolymers of unsaturated hydrocarbons; Derivatives thereof
• CPC Class Codes: C08L 71/02 Polyalkylene oxides
• CPC Class Codes: C09J 123/0853 Vinylacetate
• CPC Class Codes: C09J 123/20 having four to nine carbon atoms
• CPC Class Codes: C09J 123/22 Copolymers of isobutene; Butyl rubber ; Homo- or copolymers of other iso-olefines
• CPC Class Codes: C09J 2301/414 presence of a copolymer
• CPC Class Codes: C09J 2423/04 Presence of homo or copolymers of ethene
• CPC Class Codes: C09J 2423/10 Presence of homo or copolymers of propene
• CPC Class Codes: C09J 2431/00 Presence of polyvinyl acetate
• CPC Class Codes: C09J 7/381 based on macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• CPC Class Codes: Y10T 428/2848 Three or more layers
• CPC Class Codes: Y10T 428/2878 including addition polymer from unsaturated monomer
• CPC Class Codes: Y10T 428/2883 including addition polymer of diene monomer [e.g., SBR, SIS, etc.]

Abstract

The present invention relates to a pressure sensitive, hot melt processable adhesive composition comprising a polar plasticising oil, a polar polyethylene copolymer and polyisobutylene and a layered adhesive construction and a medical device comprising the adhesive composition according to the invention.

Claims

1. A pressure sensitive, hot melt processable adhesive composition comprising a polar plasticising oil or a combination of polar plasticising oils in the content of above 10% (w/w) of the final adhesive, and at least one polar polyethylene copolymer, and polyisobutylene, wherein the content of the polar polyethylene copolymer is 10-45% (w/w) of the final adhesive, the polar polyethylene copolymer has a melt flow index below 2 g/10 min (190°

C./21.1 N), and the polar polyethylene copolymer is ethylene vinyl acetate (EVA) with a vinyl acetate content of 40-80% (w/w), and further wherein the pressure sensitive, hot melt processable adhesive composition is substantially free of tackifier resin.

2. The pressure sensitive adhesive composition according to claim 1, wherein the final adhesive in continuous form exhibits a moisture vapour transmission rate of at least 100 g/m²/day for a 150 μ

m adhesive sheet when measured according to MVTR Test Method.

3. The pressure sensitive adhesive composition according to claim 1, wherein the polar polyethylene copolymer has a molecular weight of above 250,000 g/mol.

4. The pressure sensitive adhesive composition according to claim 1, wherein the polar plasticising oil is selected from the group of liquid rosin derivatives, aromatic olefin oligomers, vegetable and animal oils and derivatives.

5. The pressure sensitive adhesive composition according to claim 4, wherein the content of the polar plasticising oil is 20-70% (w/w) of the final adhesive.

6. The pressure sensitive adhesive composition according to claim 1, wherein the content of the polyisobutylene is 1-30% (w/w) of the final adhesive.

7. The pressure sensitive adhesive composition according to claim 1, wherein the polyisobutylene has a molecular weight of below 100,000 g/mol.

8. The pressure sensitive adhesive according to claim 7, wherein the polyisobutylene has a molecular weight of 40,000-60,000 g/mol.

9. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises a polymer with MFI>

2 (190°

C./21.1 N).

10. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises an apolar resin compatible with the polyisobutylene section of the adhesive such as hydrogenated hydrocarbon resins.

11. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises an additional plasticiser selected from the group of mineral oil, citrate oil, paraffin oil, phatalic acid esters, adepic acid esters, and liquid or solid resin.

12. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises a polyethylene wax.

13. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises other ingredients selected from the group of antioxidants, stabilisers, fillers, pigments, flow modifiers, and active ingredients.

14. The pressure sensitive adhesive composition according to claim 13, wherein the other ingredients are polar active ingredients.

15. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises absorbing particles selected from the group of hydrocolloids.

16. The pressure sensitive adhesive composition according to claim 15, wherein the amount of hydrocolloid is below 60% w/w of the total composition.

17. The pressure sensitive adhesive composition according to claim 1, wherein the composition further comprises a water soluble salt.

18. The pressure sensitive adhesive composition according to claim 17, wherein the water soluble salt is selected from the group consisting of NaCl, CaCl₂, K₂SO₄, NaHCO₃, Na₂CO₃, KCl, NaBr, NaI, KI, NH₄Cl, AlCl₃ and mixtures thereof.

19. The pressure sensitive adhesive composition according to claim 17, wherein the water soluble salt is selected from the group consisting of CH₃COONa, CH₃COOK, COONa, COOK and mixtures thereof.

20. A layered adhesive construction comprising a backing layer and at least one layer of a pressure sensitive adhesive composition according to claim 1.

21. The layered adhesive construction according to claim 20, wherein the construction further comprises at least one layer of a water absorbing adhesive.

22. The layered adhesive construction according to claim 21, wherein a layer of a pressure sensitive adhesive composition is between a layer of a water absorbing adhesive and the skin, the pressure sensitive adhesive composition comprising a polar plasticising oil or a combination of polar plasticizing oils in the content of above 10% (w/w) of the final adhesive, and at least one polar polyethylene copolymer, and polyisobutylene, wherein the content of the polar polyethylene copolymer is 10-45% (w/w) of the final adhesive, the polar polyethylene copolymer has a melt flow index below 2g/10 min (190°

C./21.1 N ), and the polar polyethylene copolymer is ethylene vinyl acetate (EVA) with a vinyl acetate content of 40-80% (w/w), and further wherein the pressure sensitive, hot melt processable adhesive composition is substantially free of tackifier resin.

23. A medical device comprising a pressure sensitive adhesive composition according to claim 1 and a backing layer.

24. The medical device according to claim 23, wherein the backing layer is non-vapour permeable.

25. The medical device according to claim 23, wherein the backing layer is water vapour permeable and has a moisture vapour transmission rate above 500 g/m²/24 h.

26. The medical device according to claim 23, wherein the medical device is a dressing, an ostomy appliance, a prosthesis, a urine collecting device, a faecal management device, a measuring instrument or a therapeutic instrument, a medical tape, or a dressing or bandage for sealing around a medical device on the skin.

27. The pressure sensitive adhesive according to claim 1, wherein the polar plasticizing oil is selected from the group consisting of esters, ethers, and glycols.

28. The pressure sensitive adhesive according to claim 1, wherein the polar plasticizing oil is selected from the group consisting of polypropylene oxides.

29. The pressure sensitive adhesive according to claim 28, wherein the polar plasticizing oil is alpha-butoxy-polyoxypropylene.

30. A pressure sensitive, hot melt processable adhesive composition produced by mixing a polar plasticising oil or a combination of polar plasticising oils in the content of above 10% (w/w) of the final adhesive, and at least one polar polyethylene copolymer, and polyisobutylene, wherein the content of the polar polyethylene copolymer is 10-45% (w/w) of the final adhesive, the polar polyethylene copolymer has a melt flow index below 2 g/10 min (190°

C./21.1 N), and the polar polyethylene copolymer is ethylene vinyl acetate (EVA) with a vinyl acetate content of 40-80% (w/w), and further wherein the pressure sensitive, hot melt processable adhesive composition is substantially free of tackifier resin.