Magnetic resonance imaging apparatus

• US 8,624,591 B2
• Filed: 02/11/2011
• Issued: 01/07/2014
• Est. Priority Date: 02/12/2010
• Status: Expired

• Current Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Toshiba Medical Systems Corporation (Canon Inc.), Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Kimura, Tokunori
• Primary Examiner(s): Vargas, Dixomara
• Application Number:
  US13/025,629
• Publication Number:
  US 20110199082A1
• Time in Patent Office: 1,061 Days
• Field of Search: 324300-322
• US Class Current: 324/306
• CPC Class Codes: A61B 5/0263 using NMR
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/5602 by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse
• CPC Class Codes: G01R 33/56333 Involving spatial modulation of the magnetization within an imaged region, e.g. spatial modulation of magnetization [SPAMM] tagging perfusion imaging based on arterial spin tagging G01R33/56366

Abstract

Provided is an MRI apparatus. In the MRI apparatus, a data collection unit repetitively performs a tag mode of applying an RF wave to at least an upstream portion of an imaging area to perform fluid labeling of a fluid flown into the imaging area and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection, while changing the inversion time. An image reconstruction unit reconstructs a plurality of tag images corresponding to a plurality of different inversion times based on the magnetic resonance data collected in the tag mode. A reference image generation unit generates a reference image based on the plurality of the tag images. A fluid image generation unit generates a subtraction image between each of the tag images and the reference image as a fluid image.

Claims

1. A magnetic resonance imaging apparatus comprising:

a data collection unit that repetitively performs a tag mode of applying an RF wave to at least an upstream portion of an imaging area to label a fluid flown into the imaging area and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection, while changing the inversion time;

an image reconstruction unit that reconstructs a plurality of tag images corresponding to a plurality of different inversion times based on magnetic resonance data collected in the tag mode;

a reference image generation unit that generates a reference image based on the plurality of the tag images; and

a fluid image generation unit that generates a subtraction image between each of the tag images and the reference image as a fluid image.

2. The magnetic resonance imaging apparatus according to claim 1,

wherein the reference image generation unit generates the reference image by using the tag image exhibiting a small difference in signal intensity between a blood flow portion and a background tissue among the plurality of the tag images.

3. The magnetic resonance imaging apparatus according to claim 1, further comprising:

a display unit that displays a plurality of the fluid images generated by the fluid image generation unit as behavior expression in a cine display format or a parallel display format.

4. The magnetic resonance imaging apparatus according to claim 1,

wherein at the time of performing the tag mode, the data collection unit applies a non-selective inversion recovery pulse to a range including the imaging area and the fluid flown into the imaging area so that the magnetic resonance data collection is started at the time when a longitudinal magnetization of at least one type of tissue among tissues included in the imaging area becomes nearly zero.

5. The magnetic resonance imaging apparatus according to claim 1,

wherein the data collection unit applies a saturation pulse to a range including the imaging area just before the magnetic resonance data collection is started.

6. The magnetic resonance imaging apparatus according to claim 1,

wherein the reference image generation unit selects among the tag images an image obtained before the fluid is flown into the imaging area or an image obtained after magnetization of the fluid in the imaging area is relaxed, and generates the reference image based on the selected image.

7. The magnetic resonance imaging apparatus according to claim 6,

wherein the reference image generation unit selects a plurality of images obtained before the fluid is flown into the imaging area or a plurality of images obtained after magnetization of the fluid in the imaging area is relaxed, and generates an average image of the plurality of the selected images as the reference image.

8. The magnetic resonance imaging apparatus according to claim 1,

wherein the data collection unit further performs a control mode a given number of times that is smaller than the number of performances of the tag mode, the control mode being an imaging mode of applying an RF wave to the imaging area without labeling a fluid through application of an RF wave to an upstream portion of the imaging area and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection,

wherein the image reconstruction unit further reconstructs control images as many as a number smaller than that of the tag images, based on the magnetic resonance data collected in the control mode,

wherein the reference image generation unit generates one reference image or a plurality of control images for subtraction corresponding to the plurality of different inversion times by using the control images as many as a number smaller than that of the tag images, and

wherein the fluid image generation unit generates a subtraction image between each of the tag images and the reference image or generates a subtraction image between the tag image and the generated control image for each inversion time.

9. The magnetic resonance imaging apparatus according to claim 8,

wherein the data collection unit performs the control mode under a collection condition which is the same as the collection condition used at the time of performing the tag mode.

10. The magnetic resonance imaging apparatus according to claim 1,

wherein the data collection unit uses Steady State Free Precession (SSFP), Gradient Echo (GRE), Fast Spin Echo (FSE), or Echo Planar Imaging (EPI) as an imaging sequence for magnetic resonance data collection.

11. The magnetic resonance imaging apparatus according to claim 1,

wherein the fluid image generation unit further performs longitudinal relaxation correction on the fluid image according to the inversion time based on a T1 value of the fluid.

12. The magnetic resonance imaging apparatus according to claim 1,

wherein the data collection unit applies the RF wave for performing the fluid labeling to the upstream portion or downstream portion of the imaging area and applies no RF wave to the imaging area until a predetermined inversion time elapses from application of the RF wave.

13. A magnetic resonance imaging apparatus comprising:

a data collection unit that repetitively performs a control mode of applying an RF wave to an imaging area without labeling a fluid through application of an RF wave to an upstream portion of the imaging area and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection, while changing the inversion time;

an image reconstruction unit that reconstructs a plurality of control images corresponding to a plurality of different inversion times based on the magnetic resonance data collected in the control mode;

a reference image generation unit that generates a reference image based on the plurality of the control images; and

a fluid image generation unit that generates subtraction images between each of the control images and the reference image as fluid images.

14. The magnetic resonance imaging apparatus according to claim 13,

wherein the reference image generation unit generates the reference image by using the control image exhibiting a small difference in signal intensity between a blood flow portion and a background tissue among the plurality of the control images.

15. The magnetic resonance imaging apparatus according to claim 13, further comprising:

a display unit that displays a plurality of the fluid images generated by the fluid image generation unit as behavior expression in a cine display format or a parallel display format.

16. The magnetic resonance imaging apparatus according to claim 13,

wherein at the time of performing the control mode, the data collection unit applies a non-selective inversion recovery pulse to a range including the imaging area and the fluid flown into the imaging area so that the magnetic resonance data collection is started at the time when a longitudinal magnetization of at least one type of tissue among tissues included in the imaging area becomes nearly zero.

17. The magnetic resonance imaging apparatus according to claim 13,

wherein the data collection unit applies a saturation pulse to a range including the imaging area just before the magnetic resonance data collection is started.

18. The magnetic resonance imaging apparatus according to claim 13,

wherein the reference image generation unit selects among the control images an image obtained before the fluid is flown into the imaging area or an image obtained after magnetization of the fluid in the imaging area is relaxed, and generates the reference image based on the selected image.

19. The magnetic resonance imaging apparatus according to claim 18,

wherein the reference image generation unit selects a plurality of images obtained before the fluid is flown into the imaging area or a plurality of images obtained after magnetization of the fluid in the imaging area is relaxed, and generates an average image of the plurality of the selected images as the reference image.

20. A magnetic resonance imaging apparatus comprising:

a data collection unit that repetitively performs an imaging mode of applying an RF wave to a subject to label a fluid flown into the subject and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection while changing the inversion time;

an image reconstruction unit that reconstructs a plurality of images corresponding to a plurality of different inversion times based on the magnetic resonance data;

a reference image generation unit that generates a reference image based on the plurality of the images; and

a fluid image generation unit that generates a subtraction image between each of the images and the reference image as a fluid image.

21. A magnetic resonance imaging apparatus comprising:

a data collection unit that repetitively performs an imaging mode of applying an RF wave to a subject to label a fluid flown into the subject and, after a lapse of an inversion time from application of the RF wave, performing magnetic resonance data collection of an imaging area while changing the inversion time;

an image reconstruction unit that reconstructs a plurality of images corresponding to a plurality of different inversion times based on the magnetic resonance data;

a fluid image generation unit that generates a fluid image by generating a subtraction image between at least one of the plurality of the images and a reference image, the reference image being an image obtained before the labeled fluid is flown into the imaging area or an image obtained after magnetization of a fluid in the imaging area is relaxed.