Method of drying bioabsorbable coating over stents
First Claim
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1. A method of coating a stent, comprising:
- applying a composition to a stent substrate, the composition including a polymer component and a solvent;
exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component, wherein the exposing removes solvent from the applied composition,wherein the exposing comprises blowing a heated gas on the polymer component to heat the polymer component to a temperature equal to or greater than the Tg of the polymer component; and
repeating the applying and exposing one or more times to form a coating, wherein the solvent content of the coating after the final exposing step is at a level suitable for a finished stent.
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Abstract
Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
71 Citations
17 Claims
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1. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent; exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component, wherein the exposing removes solvent from the applied composition, wherein the exposing comprises blowing a heated gas on the polymer component to heat the polymer component to a temperature equal to or greater than the Tg of the polymer component; and repeating the applying and exposing one or more times to form a coating, wherein the solvent content of the coating after the final exposing step is at a level suitable for a finished stent. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly applied to surfaces of the stent substrate; thermally treating the applied composition, wherein the thermal treatment removes solvent from the applied composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein a duration of each of the thermal treatments is less than 60 s, wherein the polymer component is a bioabsorbable polymer. - View Dependent Claims (8, 9, 10)
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11. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly applied to surfaces of the stent substrate; thermally treating the applied composition, wherein the thermal treatment removes solvent from the applied composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein a duration of each of the thermal treatments is less than 60 s, wherein the stent is not baked after the final repetition of the thermal treatment.
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12. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly applied to surfaces of the stent substrate; thermally treating the applied composition, wherein the thermal treatment removes solvent from the applied composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein a duration of each of the thermal treatments is less than 60 s, wherein no additional thermal treatment of the stent is performed after the final repetition of the thermal treatment.
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13. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly applied to surfaces of the stent substrate; thermally treating the applied composition, wherein the thermal treatment removes solvent from the applied composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein a duration of each of the thermal treatments is less than 60 s, wherein the thermal treatment comprises exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component.
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14. A method of coating a stent, comprising:
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applying a composition to a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly applied to surfaces of the stent substrate; thermally treating the applied composition, wherein the thermal treatment removes solvent from the applied composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein a duration of each of the thermal treatments is less than 60 s, wherein no additional thermal treatment involving exposure of the stent to a temperature greater than 40°
C. is performed or no additional thermal treatment involving exposure for greater than 60 s is performed on the stent.
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15. A method of coating a stent, comprising:
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depositing a composition onto a stent substrate, the composition including a polymer component and a solvent, wherein the composition is uniformly deposited to surfaces of the stent substrate; blowing a heated gas onto the deposited composition, wherein the heated gas removes solvent from the deposited composition; and repeating the applying and thermal treatment one or more times to form a coating, wherein the coating comprises less than 2 wt% solvent, wherein further processing steps do not include baking the stent to remove residual solvent. - View Dependent Claims (16, 17)
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Specification