Embeddable modules for measuring blood glucose levels

• US 8,636,661 B2
• Filed: 06/04/2009
• Issued: 01/28/2014
• Est. Priority Date: 06/04/2009
• Status: Expired due to Fees

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Batman, Carol, Ramey, Blaine Edward, Engelhardt, Timothy Peter, Cadio, Michel A., Moore, Steven Kent, Collins, Ricky Lee, Brown, Michael L.
• Primary Examiner(s): Krass, Frederick
• Assistant Examiner(s): Parad, Dennis J
• Application Number:
  US12/477,982
• Publication Number:
  US 20100312082A1
• Time in Patent Office: 1,699 Days
• Field of Search: 710/63
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 2560/0456 Apparatus provided with a docking unit
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
• CPC Class Codes: A61B 2562/08 Sensors provided with means for identification, e.g. barcodes or memory chips
• CPC Class Codes: A61B 2562/085 combined with means for recording calibration data
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes

Abstract

An embeddable module for measuring a blood glucose level may be embedded in an external host and may comprise a host interface, a microcontroller, an ASIC, a temperature measuring element, and a measurement strip port. The host interface may permit electrical communication between the host and the microcontroller. The microcontroller and ASIC may communicate with each other and may work together to measure the blood glucose level of a blood sample. The measurement strip port may receive a removable measurement strip having the blood sample. The ASIC may communicate with the measurement strip port such that the ASIC may receive signals from the measurement strip port related to the blood glucose level of the blood sample. The temperature measuring element may be in electrical communication with the microcontroller and may measure the temperature of the module and transmit signals to the microcontroller related to the temperature of the module.

Claims

1. A blood glucose measurement module embeddable in an external host for measuring a blood glucose level of a blood sample provided on a disposable measurement strip, the module consisting of:

a host interface;

a microcontroller;

an application-specific integrated circuit (ASIC);

a temperature measuring element;

a measurement strip port,

an external code key separate from the measurement strip and configured to contain calibration information related to the measurement strip,

a code key port configured to receive the external code key wherein the code key port resides completely within a housing of the host; and

a non-volatile memory;

wherein;

the host interface is operable to permit electrical communication between the host and the microcontroller such that the module is operable to transmit a result of a blood glucose level measurement to the host and the module is operable to send to the host an event interrupt signal to indicate to the host that an event has occurred on the module and to send to the host a module ready signal to indicate to the host that the module is ready to receive a message from the host, wherein the event comprises detecting insertion of the measurement strip into the measurement strip port;

the microcontroller is in electrical communication with the ASIC wherein the microcontroller and the ASIC are operable to measure the blood glucose level of the blood sample,

the measurement strip port is operable to receive the disposable measurement strip having the blood sample,

the ASIC is in electrical communication with the measurement strip port such that the ASIC is operable to receive signals from the measurement strip port related to the blood glucose level of the blood sample provided on the measurement strip,

the temperature measuring element is in electrical communication with the microcontroller and is operable to measure the temperature of the module and transmit signals to the microcontroller related to the temperature of the module; and

wherein the non-volatile memory is operable to store data relating to the operation of the module or calibration data for the measurement strip, wherein the non-volatile memory is in electrical communication with the microcontroller such that the microcontroller is operable to read data from and write data to the memory.

2. The blood glucose measurement module of claim 1 wherein:

the code key is operable to be removably connected to the module; and

the microcontroller is in electrical communication with the code key such that the microcontroller is operable to read the calibration data stored on the code key when the code key is connected to the module.

3. The blood glucose measurement module of claim 1 wherein the module is operable to request calibration data for the measurement strip from the host.

4. The blood glucose measurement module of claim 1 wherein the host is in electrical communication with the code key having calibration data for the measurement strip and is operable to communicate the calibration data to the microcontroller via the host interface.

5. The blood glucose measurement module of claim 1 wherein the microcontroller comprises a non-volatile memory operable to store data relating to the operation of the module or calibration data for the measurement strip.

6. The blood glucose measurement module of claim 1 wherein the host interface is a wired serial interface, a wired parallel interface, or an infrared serial interface.

7. The blood glucose measurement module of claim 1 wherein the host is an insulin pump, a cellular phone, a smart phone, a PDA, or a music player.

8. The blood glucose measurement module of claim 1 wherein the temperature measuring element is a semiconductor sensor, a resistance thermal device (RTD), or a thermocouple.