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Wax foamable vehicle and pharmaceutical compositions thereof

  • US 8,636,982 B2
  • Filed: 08/07/2008
  • Issued: 01/28/2014
  • Est. Priority Date: 08/07/2007
  • Status: Active Grant
First Claim
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1. A foamable emulsion composition comprising:

  • A. a carrier comprising;

    a. a liquid wax comprising at least one fatty acid or at least one fatty alcohol;

    b. a stabilizer component comprising a non ionic surface-active agent;

    c. water; and

    d. more than 7% by weight of a solid wax of the carrier selected from the group consisting of a fatty acid, a fatty alcohol, a microcrystalline wax, a paraffin wax, a petroleum wax, a polyethylene wax, beeswax, candelilla wax, castor wax, Chinese wax, Fischer-Tropsch wax, rice bran wax, tallow, wool wax and mixtures thereof; and

    B. a liquefied hydrocarbon gas propellant at a concentration of about 3% to about 35% by weight of the foamable emulsion composition;

    wherein, when the liquid wax comprises at least one fatty acid, the fatty acid is present in the composition at a concentration of more than 35% or about 35% by weight of the carrier;

    wherein, when the liquid wax comprises at least one fatty alcohol, the fatty alcohol is present in the composition at a concentration of more than 12% or about 12% by weight of the carrier;

    wherein the liquid wax enables the solid wax to solubilize;

    wherein the composition is substantially free from crystals and is sufficiently flowable;

    wherein the carrier being otherwise free of polymeric agent; and

    wherein, upon release from a pressurized container, a breakable foam is produced.

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