Polymers for reversing heparin-based anticoagulation
First Claim
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1. A method of counteracting heparin in a subject, the method comprising administering a heparin binding polymer to a subject, the heparin binding polymer comprising:
- a first dendritic polyol; and
one or more cationic moieties attached to the first dendritic polyol,wherein the polymer comprises at least one of;
a) the structure of Formula (I);
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Abstract
Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules.
13 Citations
20 Claims
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1. A method of counteracting heparin in a subject, the method comprising administering a heparin binding polymer to a subject, the heparin binding polymer comprising:
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a first dendritic polyol; and one or more cationic moieties attached to the first dendritic polyol, wherein the polymer comprises at least one of; a) the structure of Formula (I); - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification