Methods and devices for central photoplethysmographic monitoring methods

• US 8,641,635 B2
• Filed: 08/15/2006
• Issued: 02/04/2014
• Est. Priority Date: 08/15/2006
• Status: Active Grant

• Current Assignee: Beta Biomed Services, Inc., Convergent Engineering, Inc., University of Florida Research Foundation, Incorporated (State University System of Florida)
• Original Assignee: University of Florida Research Foundation, Incorporated (State University System of Florida)
• Inventors: Melker, Richard J., Euliano, Neil R.
• Primary Examiner(s): NEGIN, RUSSELL SCOTT
• Application Number:
  US12/377,706
• Publication Number:
  US 20100192952A1
• Time in Patent Office: 2,730 Days
• Field of Search: None
• US Class Current: 600/504
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/6803 Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 5/6815 Ear
• CPC Class Codes: A61B 5/6817 Ear canal
• CPC Class Codes: A61B 5/6819 Nose
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0627 with sealing means on a part of the body other than the face, e.g. helmets, hoods or domes
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/432 partial CO2 pressure (P-CO2)

Abstract

Disclosed herein are methods and devices for delivering gas to a subject and obtaining plethysmograph readings from a subject. Specifically disclosed herein are masks and helmets which comprise one or more pulse oximeter probes associated therewith. The masks and helmets may be used in particular contexts, including, but not limited to, emergency responder personnel, pilots or subjects of medical attention.

Claims

1. A method of monitoring blood flow status to the head of an individual, said method comprising:

securing a pulse oximeter probe to a central source site of said individual and generating a plethysmography waveform;

extracting an isolated DC component waveform from said plethysmography waveform with a signal processor;

monitoring blood flow at said central source site by continuously monitoring changes in said isolated DC component waveform over time; and

effecting a predetermined reaction responsive to said blood flow falling below a predefined value.

2. The method of claim 1 wherein said reaction comprises generating an alarm.

3. The method of claim 2 wherein said alarm is a visual, tactile or audible warning.

5. The method of claim 1, Wherein said monitoring blood flow comprises establishing a baseline value of plethysmography signals and comparing subsequently Obtained plethysmography signals to said baseline value.

6. The method of claim 1, further comprising sustaining and monitoring said isolated AC component waveform.

4. The method of claim l wherein said reaction comprises directing flight control systems of an aircraft to undertake a corrective flight maneuver.

7. A system for monitoring blood flow status of a subject comprising

a pulse oximeter probe that secures to a central source site of said subject and generates a plethysmography waveform;

a signal processor in communication with said pulse oximeter probe, wherein said signal processor extracts an isolated DC component waveform from said plethysmography waveform and sustains said isolated DC component waveform and, optionally, an isolated AC component waveform; and

an analyzer unit in communication with said signal processor, wherein said analyzer unit monitors blood flow by continuously evaluating changes in said isolated DC component waveform and, optionally, said isolated AC component waveform, over time.

8. A system for monitoring blood flow comprising

a mask that delivers gas to a subject, said mask comprising a compartment that covers the nose and/or mouth of said subject and an airhose attached to said compartment;

and

a pulse oximeter probe that secures to a central source site of said subject and generates a plethysmography waveform, said pulse oximeter probe associated with said mask,

a signal processor in communication with said pulse oximeter probe that extracts an isolated DC component waveform from said plethysmography waveform and sustains said isolated DC component waveform and, optionally, an isolated AC component waveform; and

an analyzer unit in communication with said signal processor, wherein said analyzer unit monitors blood flow by continuously evaluating changes in said isolated DC component waveform and, optionally, said isolated AC component waveform, over time.

9. The system of claim 8, wherein said pulse oximeter probe secured to said subject'"'"'s nasal alar and comprises:

an elongated base positioned along said subject'"'"'s nasal ridge, said elongated base comprising a proximal end and a distal end;

a bridge attached to or integral with said proximal end of said elongated base, said bridge having a right end portion and a left end portion;

a right flap extending from said right end portion of said bridge;

a left flap extending from said left end portion of said bridge;

at least one LED disposed in either said right flap or said left flap, or both; and

at least one wing fold extending down from either said right flap or said left flap, or both, said at least one wing fold comprising at least one photodetector disposed thereon and inserted into said user'"'"'s right or left nostril such that said at least one photodetector is aligned across from said at least one LED.

10. The system of claim 9, wherein said pulse oximeter probe comprises

a first wing fold extending down from either said right flap or said left flap, said first wing fold comprising at least one photodetector disposed thereon and inserted into said subject'"'"'s right or left nostril;

and

a second wing fold extending down from either said right flap or said left flap, whichever said first flap is not extending down from, and inserted into said user'"'"'s right or left nostril, wherein said first wing fold and said second wing fold are sufficiently rigid so as to hold their shape upon insertion into said user'"'"'s nostrils.

11. The system of claim 8, further comprising a connector attached to or integrated at the proximal end of said elongated base, said connecter attached and in electrical communication with a corresponding receptacle.

12. The system of claim 8, where said mask further comprises a strap that holds said mask to said subject'"'"'s face and wherein said pulse oximeter probe is a reflectance probe associated with said strap, said reflectance probe located along said strap so as to facilitate obtaining readings from said subject'"'"'s pre-auricular region or post-auricular region.

13. The system of claim 12, wherein said reflectance probe comprises

a probe base structure attached to or integrated with said strap;

at least one LED disposed on said probe base structure; and

at least one photodetector disposed on said probe base structure and spaced proximally up from said at least one LED disposed on said probe base structure.

14. The system of claim 13, further comprising a connector attached to or integrated with a proximal end of a wiring harness.

15. The system of claim 13, wherein said at least one LED is positioned distal to said at least one photodetector at a spacing in the range of about 5 mm to about 30 mm.

16. The system of claim 13, wherein said at least one LED is positioned distal to said at least one photodetector at a spacing in the range of about 8 min to about 20 mm.

17. The system of claim 13, wherein said at least one LED is positioned distal to said photodetector at a spacing in the range of about 10 mm to about 12 mm.

18. The system of claim 8, wherein said probe is communicatingly connected to a wireless transmitter.

19. The system of claim 8, wherein said probe comprises a battery.

20. A system for monitoring signals indicative of blood flow at least one central source site of at least one subject, said system comprising

a mask that delivers gas to said subject;

at least one pulse oximeter probe that secures to a central source site of said subject and generates a plethysmography waveform; and

a remote monitoring computer communicatingly connected with said at least one pulse oximeter probe, wherein said remote monitoring computer processes said plethysmography waveform,

wherein said remote monitoring computer extracts an isolated DC component waveform, and monitors blood flow by continuously evaluating changes in said isolated DC component waveform over time.

21. The system of claim 20, wherein said at least one subject is an emergency responder and said at least one puke oximeter probe comprises a wireless transmitter.

22. The system of claim 20, wherein said at least one subject is a patient in a medical facility.

23. The system of claim 20, wherein said remote monitoring computer determines determine oxygen saturation.

24. The system of claim 20, wherein said mask further comprises a capnography sensor associated therewith, said capnography sensor being communicatingly connected to said remote monitoring computer.

25. The system of claim 20, wherein said mask further comprises a sampling apparatus to obtain exhaled gases for determination of carbon dioxide content within said mask and communicatingly connected to a capnography analyzer.

26. The system of claim 25, wherein said remote monitoring computer is communicatingly connected to said capnography analyzer and configured to process signals from said capnography analyzer.

27. A mask for delivering gas to a subject, said mask comprising

a nasal delivery portion;

at least one projection associated with said nasal delivery portion that inserts into at least one nasal passage;

an airhose associated with said nasal delivery portion; and

a pulse oximeter probe that secures to a central source site of said subject, said pulse oximeter probe associated with said mask,

a signal processor in communication with said pulse oximeter probe that extracts an isolated DC component waveform from said plethysmography waveform and sustains said isolated DC component waveform and, optionally, an isolated AC component waveform; and

an analyzer unit in communication with said signal processing unit, wherein said analyzer unit monitors blood flow by continuously evaluating changes in said isolated DC component waveform and, optionally, said AC component waveform, over time.

28. The system of claim 27, further comprising a strap that holds said mask to said subject'"'"'s face and wherein the pulse oximeter probe is a reflectance probe associated with said strap, said reflectance probe located along said strap so as to facilitate obtaining readings from said subject'"'"'s pre-auricular region or post-auricular region.

29. The system of claim 27, wherein said mask further comprises a wire connected to said probe, a battery connected to said wire and a wireless transmitter communicatingly connected to said probe.