Catheter with laminar flow drug delivery properties
First Claim
Patent Images
1. A catheter comprising:
- an elongate tubular member comprising a proximal end, a distal end and a lumen extending from the proximal end to the distal end; and
an elongate cylindrical member disposed at least partially within the lumen of the elongate tubular member and having a proximal end, a distal end and a delivery assembly extending from the distal end, wherein the delivery assembly comprises a flared conical shaped member, and wherein a fluid delivery lumen within the elongate cylindrical member opens to a plurality of tubular fluid delivery channels disposed within the flared conical shaped member,wherein the tubular fluid delivery channels are embedded within a wall of the flared conical shaped member, each of the tubular fluid delivery channels terminate at a fluid exit opening, each fluid exit opening is formed in the wall of the flared conical shaped member and discharges liquid received from the fluid delivery lumen out of the fluid exit opening to deliver a bioactive agent to a patient, and each fluid exit opening faces in a distal direction away from the distal end of the elongate cylindrical member.
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Abstract
Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed.
36 Citations
15 Claims
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1. A catheter comprising:
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an elongate tubular member comprising a proximal end, a distal end and a lumen extending from the proximal end to the distal end; and an elongate cylindrical member disposed at least partially within the lumen of the elongate tubular member and having a proximal end, a distal end and a delivery assembly extending from the distal end, wherein the delivery assembly comprises a flared conical shaped member, and wherein a fluid delivery lumen within the elongate cylindrical member opens to a plurality of tubular fluid delivery channels disposed within the flared conical shaped member, wherein the tubular fluid delivery channels are embedded within a wall of the flared conical shaped member, each of the tubular fluid delivery channels terminate at a fluid exit opening, each fluid exit opening is formed in the wall of the flared conical shaped member and discharges liquid received from the fluid delivery lumen out of the fluid exit opening to deliver a bioactive agent to a patient, and each fluid exit opening faces in a distal direction away from the distal end of the elongate cylindrical member. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for treating or preventing a vascular disease comprising:
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inserting a catheter into a blood vessel of a patient; and introducing a bioactive agent formulation into the blood vessel through the catheter, wherein the catheter comprises; an elongate tubular member comprising a proximal end, a distal end and a lumen extending from the proximal end to the distal end; and an elongate cylindrical member disposed at least partially within the lumen of the elongate tubular member and having a proximal end, a distal end and a delivery assembly extending from the distal end, wherein the delivery assembly comprises a lumen within the elongate cylindrical member that opens to a plurality of tubular channels which cumulatively release the bioactive agent formulation into the blood vessel, wherein the tubular channels are embedded within a wall of a flared conical shaped member of the delivery assembly, and outlets of the tubular channels, from which the bioactive agent formulation is released, are formed in the wall and face in a distal direction away from the distal end of the elongate tubular member. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15)
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Specification