Transdermal porator and patch system and method for using same
First Claim
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1. A transdermal permeant delivery system comprising:
- i) a disposable substratedefining a poration area andhaving an upper substrate surface, a lower substrate surface, a conduit that extends between the upper substrate surface and the lower substrate surface, andat least one channel disposed on the upper substrate surface and in fluid communication with the conduit so that a vacuum, generated by a vacuum source to be provided to the system, is delivered to the poration area via the conduit and the at least one channel;
ii) a first release liner having a top surface and an opposed bottom surface, wherein at least a portion of the bottom surface of the first release liner is connected to the upper substrate surface; and
iii) a patch that is selectively removable from the top surface of the first release liner, the patch comprising;
a) a backing layer having an upper surface and an opposed lower surface, andb) a reservoir mounted thereon a portion of the lower surface of the backing layer and configured for releaseably containing at least one permeant;
wherein, in a connected position, at least a portion of the backing layer of the patch is releaseably mounted thereto the top surface of the first release liner in spaced registration with the poration area of the substrate.
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Abstract
A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
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Citations
14 Claims
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1. A transdermal permeant delivery system comprising:
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i) a disposable substrate defining a poration area and having an upper substrate surface, a lower substrate surface, a conduit that extends between the upper substrate surface and the lower substrate surface, and at least one channel disposed on the upper substrate surface and in fluid communication with the conduit so that a vacuum, generated by a vacuum source to be provided to the system, is delivered to the poration area via the conduit and the at least one channel; ii) a first release liner having a top surface and an opposed bottom surface, wherein at least a portion of the bottom surface of the first release liner is connected to the upper substrate surface; and iii) a patch that is selectively removable from the top surface of the first release liner, the patch comprising; a) a backing layer having an upper surface and an opposed lower surface, and b) a reservoir mounted thereon a portion of the lower surface of the backing layer and configured for releaseably containing at least one permeant; wherein, in a connected position, at least a portion of the backing layer of the patch is releaseably mounted thereto the top surface of the first release liner in spaced registration with the poration area of the substrate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification