System and method to define target volume for stimulation in brain
First Claim
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1. A computer-implemented method comprising:
- storing in a memory device a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients;
receiving, by a computer processor, patient data for a given patient, the patient data representing an assessment of a patient condition; and
evaluating, by the computer processor, the VTA data structure relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient;
wherein the VTA data structure comprises a plurality of statistical atlases, each of the plurality of statistical atlases comprising data that statistically characterizes a therapeutic effect for a plurality of VTAs acquired for the plurality of patients, and the plurality of statistical atlases are hierarchically organized according to one or more categories and a plurality of subcategories.
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Abstract
One embodiment provides a computer-implemented method that includes storing a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients. Patient data is received for a given patient, the patient data representing an assessment of a patient condition. The VTA data structure is evaluated relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient.
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Citations
21 Claims
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1. A computer-implemented method comprising:
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storing in a memory device a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients; receiving, by a computer processor, patient data for a given patient, the patient data representing an assessment of a patient condition; and evaluating, by the computer processor, the VTA data structure relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient; wherein the VTA data structure comprises a plurality of statistical atlases, each of the plurality of statistical atlases comprising data that statistically characterizes a therapeutic effect for a plurality of VTAs acquired for the plurality of patients, and the plurality of statistical atlases are hierarchically organized according to one or more categories and a plurality of subcategories. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A system for determining a volume of tissue activation for achieving a desired therapeutic effect for a given patient, the system comprising:
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a volume of tissue activation (VTA) data structure stored in memory, the VTA data structure being derived from analysis anatomical and electrical data acquired for a plurality of patients; patient data stored in the memory, the patient data representing an assessment of a patient condition for the given patient; and a processor programmed to execute instructions for; evaluating the VTA data structure relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient; and determining at least one of a structural parameter and a stimulation parameter that can provide a design VTA for the given patient that substantially matches the target VTA; wherein the VTA data structure comprises a plurality of statistical atlases, each of the plurality of statistical atlases comprising data that statistically characterizes a therapeutic effect for a plurality of VTAs acquired for the plurality of patients, and the plurality of statistical atlases are hierarchically organized according to one or more categories and a plurality of subcategories. - View Dependent Claims (19, 20, 21)
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Specification