Nitric oxide delivery system
First Claim
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1. A system for delivering a therapeutic amount of nitric oxide, comprising:
- a liquid reservoir containing dinitrogen tetroxide;
a tube coupled to the reservoir;
a first ribbed tube coupled to the tube, wherein the first ribbed tube comprises;
a plurality of hollow ribs,wherein each rib comprises a volume, a base and a length that is a distance across the base of the rib; and
a surface-active material with a reducing agent, wherein a volume of the surface-active material is within each rib and a height of the surface-active material within each rib is a distance above the base of each rib the surface-active material extends into the rib, and wherein the length of each rib is less than twice the distance above the base of each rib the surface-active material extends into the rib, and the volume of each rib is greater than the volume of the surface-active material within each rib; and
a patient interface coupled to the first ribbed tube, wherein the first ribbed tube is configured to convert nitrogen dioxide in a gas flow into nitric oxide prior to reaching the patient interface.
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Abstract
An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual'"'"'s lungs.
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Citations
38 Claims
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1. A system for delivering a therapeutic amount of nitric oxide, comprising:
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a liquid reservoir containing dinitrogen tetroxide; a tube coupled to the reservoir; a first ribbed tube coupled to the tube, wherein the first ribbed tube comprises; a plurality of hollow ribs, wherein each rib comprises a volume, a base and a length that is a distance across the base of the rib; and a surface-active material with a reducing agent, wherein a volume of the surface-active material is within each rib and a height of the surface-active material within each rib is a distance above the base of each rib the surface-active material extends into the rib, and wherein the length of each rib is less than twice the distance above the base of each rib the surface-active material extends into the rib, and the volume of each rib is greater than the volume of the surface-active material within each rib; and a patient interface coupled to the first ribbed tube, wherein the first ribbed tube is configured to convert nitrogen dioxide in a gas flow into nitric oxide prior to reaching the patient interface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A device for delivering nitric oxide to a patient comprising:
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a liquid reservoir containing dinitrogen tetroxide; a tube coupled to the reservoir, wherein the tube coupled to the reservoir has a bore size of about 25 microns or less; a first ribbed tube coupled to the tube, the first ribbed tube comprising a surface-active material saturated with an aqueous solution of an antioxidant and a plurality of ribs, wherein the volume within each rib is greater than the a volume of the surface-active material within each rib a plurality of hollow ribs, wherein each rib comprises a volume, a base and a length that is a distance across the base of the rib; and a surface-active material saturated with an aqueous solution of an antioxidant, wherein a volume of the surface-active material is within each rib and a height of the surface-active material within each rib is a distance above the base of each rib the surface-active material extends into the rib, and the length of each rib is less than twice the distance above the base of each rib the surface-active material extends into the rib, and the volume of each rib is greater than the volume of the surface-active material within each rib; and a patient interface coupled to the first ribbed tube, wherein the first ribbed tube is configured to convert nitrogen dioxide in a gas flow into nitric oxide prior to reaching the patient interface. - View Dependent Claims (30, 31, 32, 33)
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34. A ribbed tube comprising a body having a first end and a second end, wherein the body comprises
multiple hollow concentric ribs, wherein each rib comprises a base and a length that is a distance across the base of the rib, and each rib comprises a volume; - and
a surface-active material, wherein a volume of the surface-active material is within each rib and a height of the surface-active material within each rib is a distance above the base of each rib the surface-active material extends into the rib, and wherein the length of each rib is less than twice the distance above the base of each rib the surface-active material extends into the rib, and the volume of each rib is greater than the volume of the surface-active material within each rib. - View Dependent Claims (35, 36, 37, 38)
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Specification