Ultrasound scanning capsule endoscope (USCE)

• US 8,647,259 B2
• Filed: 03/28/2011
• Issued: 02/11/2014
• Est. Priority Date: 03/26/2010
• Status: Active Grant

• Current Assignee: Innurvation Incorporated
• Original Assignee: Innurvation Incorporated
• Inventors: Arneson, Michael, Bandy, William, Shanks, Wayne
• Primary Examiner(s): Cattungal, Sanjay
• Application Number:
  US13/073,424
• Publication Number:
  US 20120101386A1
• Time in Patent Office: 1,051 Days
• Field of Search: 600437-469, 600107-118, 600/160, 600165-177, 600/593
• US Class Current: 600/109
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4472 Wireless probes
• CPC Class Codes: A61B 8/4488 the transducer being a phased array
• CPC Class Codes: G01S 15/8915 using a transducer array
• CPC Class Codes: G01S 15/8993 Three dimensional imaging systems
• CPC Class Codes: G01S 7/003 Transmission of data between radar, sonar or lidar systems and remote stations
• CPC Class Codes: G01S 7/52017 particularly adapted to short-range imaging G01S7/53 takes precedence
• CPC Class Codes: G01S 7/52065 Compound scan display, e.g. panoramic imaging

Abstract

The present invention relates to ultrasound imaging on a capsule endoscope platform. It relates to the generation of a focused ultrasound acoustic signal and the receiving of echo signals from the wall of a body lumen with an array of acoustic transducers wrapped around the circumference of the capsule. It relates to sending the generated echo image signals to receiver devices attached or worn on the body. It relates to the generation of 360° overlapping sidewall ultrasound scans of a body lumen, and image processing techniques to assemble these scans into a high resolution continuous ultrasound image. Finally, it relates to the manufacture and assembly of such an ultrasound scanning capsule endoscope (USCE). The concept is extendable to conventional endoscopes and catheters.

Claims

1. An ultrasound scanning capsule endoscope, comprising:

a housing configured to have a size that is ingestible;

an ultrasonic transducer array wrapped around a circumference of the housing, each transducer in the ultrasonic transducer array being configured to transmit an ultrasonic signal and to receive an echo signal;

a timing circuit configured to induce transmission of a respective ultrasonic signal by each transducer according to a phased array sequence,

wherein the phased array sequence configures the ultrasonic transducer array into consecutive phased arrays around the circumference of the housing for sequentially imaging one or more voxels at a time around the circumference, and

wherein the consecutive phased arrays utilize a number of transducers when configured for transmission of their respective ultrasonic signals that is greater than a number of transducers when configured for reception of their respective echo signals.

2. The ultrasound scanning capsule endoscope of claim 1, wherein a wavelength of the ultrasonic signal transmitted by each transducer in the ultrasonic transducer array is related to a center-to-center transducer element spacing between adjacent transducers in the ultrasonic transducer array.

3. The ultrasound scanning capsule endoscope of claim 2, wherein the wavelength of the ultrasonic signal transmitted by each transducer in the ultrasonic transducer array is a multiple of the center-to-center transducer element spacing.

4. The ultrasound scanning capsule endoscope of claim 1, wherein each transducer in the ultrasonic transducer array is configured to enter into a receive mode of operation to listen for the echo signal after transmitting its respective ultrasonic signal in a transmit mode of operation.

5. The ultrasound scanning capsule endoscope of claim 1, wherein transducers in the ultrasonic transducer array that are further away from a center of their respective consecutive phased array provide their respective ultrasonic signals before transducers in the ultrasonic transducer array that are closer to the center.

6. The ultrasound scanning capsule endoscope of claim 1, wherein the consecutive phased arrays are configured and arranged to form a plurality of quadrants around the circumference, each of the plurality of quadrants being configured to simultaneously image one or more respective voxels from among the one or more voxels.

7. The ultrasound scanning capsule endoscope of claim 1, wherein the consecutive phased arrays are configured to sequentially image the one or more voxels around the circumference until all circumference voxels have been imaged.

8. The ultrasound scanning capsule endoscope of claim 1, wherein the consecutive phased arrays maintain a common center transducer when switching between transmission and reception configurations.

9. An ultrasound scanning capsule endoscope, comprising:

an ultrasonic transducer phased array wrapped around a circumference of a housing, each transducer in the ultrasonic transducer phased array being configured to transmit an ultrasonic signal and to receive an echo signal;

a timing circuit configured to induce transmission of a respective ultrasonic signal by each transducer in the ultrasonic transducer phased array according to a phased array sequence to sequentially image one or more voxels at a time around the circumference,

wherein each phased array within the phased array sequence utilizes a number of transducers when configured for transmission of its respective ultrasonic signal that is greater than a number of transducers when configured for reception of its respective echo signal.

10. The ultrasound scanning capsule endoscope of claim 9, wherein a wavelength of the ultrasonic signal transmitted by each transducer in the ultrasonic transducer phased array is related to a center-to-center transducer element spacing between adjacent transducers in the ultrasonic transducer phased array.

11. The ultrasound scanning capsule endoscope of claim 10, wherein the wavelength of the ultrasonic signal transmitted by each transducer in the ultrasonic transducer phased array is a multiple of the center-to-center transducer element spacing.

12. The ultrasound scanning capsule endoscope of claim 9, wherein each transducer in the ultrasonic transducer phased array is configured to enter into a receive mode of operation to listen for an echo signal after transmitting its respective ultrasonic signal in a transmit mode of operation.

13. The ultrasound scanning capsule endoscope of claim 9, wherein transducers in the ultrasonic transducer phased array that are further away from a center of their respective phased array provide their respective ultrasonic signals before transducers in the ultrasonic transducer phased array that are closer to the center.

14. The ultrasound scanning capsule endoscope of claim 9, wherein the ultrasonic transducer phased array is configured and arranged to form a plurality of quadrants around the circumference, each of the plurality of quadrants being configured to simultaneously image one or more respective voxels from among the one or more voxels.

15. The ultrasound scanning capsule endoscope of claim 9, wherein the ultrasonic transducer phased array is configured to sequentially image the one or more voxels around the circumference until all circumference voxels have been imaged.

16. The ultrasound scanning capsule endoscope of claim 9, wherein each phased array within the phased array sequence maintains a common center transducer when switching between transmission and reception configurations.

17. A method for imaging an intestinal tract, comprising:

transmitting, by a first plurality of transducers, a first plurality of ultrasonic signals, each transducer from among the first plurality of transducers being part of a respective phased array from among a consecutive phased array that is wrapped around the circumference of an ultrasound scanning capsule;

receiving, by a subset of the first plurality of transducers, a first plurality of echoes resulting from the first plurality of ultrasonic signals reflecting off of the intestinal tract to image one or more first voxels of the intestinal tract;

transmitting, by a second plurality of transducers, a second plurality of ultrasonic signals each transducer from among the second plurality of transducers being part of another respective phased array from among the consecutive phased array; and

receiving, by a subset of the second plurality of transducers, a second plurality of echoes resulting from the second plurality of ultrasonic signals reflecting off of the intestinal tract to image one or more second voxels of the intestinal tract.

18. The method of claim 17, further comprising:

activating the second plurality of transducers after the first plurality of transducers have transmitted the first plurality of ultrasonic signals, the second plurality of transducers being closer to a center of their respective phased array than the first plurality of transducers.

19. The method of claim 17, further comprising:

repeating the transmitting and the receiving steps for other plurality of transducers from among the consecutive phased array until all circumference voxels have been imaged.

20. The method of claim 17, wherein the step of receiving the second plurality of echoes comprises:

receiving the second plurality of echoes to image the one or more second voxels that overlap the one or more first voxels.

21. The method of claim 17, wherein the step of transmitting the first plurality of ultrasonic signals comprises:

transmitting the first plurality of ultrasonic signals having wavelengths that are related to a center-to-center transducer element spacing between adjacent transducers in their respective phased array.

22. The method of claim 21, wherein the step of transmitting the second plurality of ultrasonic signals comprises:

transmitting the second plurality of ultrasonic signals having wavelengths that are related to a center-to-center transducer element spacing between adjacent transducers in their respective phased array.