Extracorporeal blood chamber

• US 8,647,291 B2
• Filed: 10/30/2006
• Issued: 02/11/2014
• Est. Priority Date: 10/30/2006
• Status: Active Grant

• Current Assignee: Gambro Lundia AB (Baxter International Inc.)
• Original Assignee: Gambro Lundia AB (Baxter International Inc.)
• Inventors: Ribolzi, Francesco, Sakota, Ranko, Caleffi, Luca, Franzoni, Giuseppe
• Primary Examiner(s): Deak, Leslie
• Assistant Examiner(s): Townsend, Guy K
• Application Number:
  US12/447,647
• Publication Number:
  US 20100288761A1
• Time in Patent Office: 2,661 Days
• Field of Search: 604/6.15
• US Class Current: 604/6.15
• CPC Class Codes: A61M 1/3434 with pre-dilution and post-dilution
• CPC Class Codes: A61M 1/3437 downstream of the filter, e.g. post-dilution with filtrate
• CPC Class Codes: A61M 1/3465 using dialysate as substitution fluid
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters

Abstract

An extracorporeal blood chamber (12) comprises an expansion reservoir (47) having a first access (48) arranged laterally and a second access (49) arranged on the bottom of the chamber (12). The chamber comprises, integrally with the reservoir, a first conduit terminating in the first access, a second conduit terminating in the first access, and a third conduit terminating in the second access. The extracorporeal blood enters the reservoir through the first conduit and there mixes with an infusion fluid which enters through the second conduit. The resulting mixture exits through the third conduit. The chamber is used in a hemo(dia)filtration apparatus to mix the blood optimally with the replacement fluid.

Claims

1. An extracorporeal blood chamber for use in dialysis of a patient, comprising:

(a) an expansion reservoir provided with a bottom, a top, at least a first side extending between the bottom and the top, a first access arranged on said first side at a distance from said bottom and said top, and a second access;

(b) a first blood conduit having an end and terminating in said first access, the first blood conduit adapted for connection to a blood line conveying arterial blood from the patient, the first blood conduit being effective to convey the arterial blood to the first access;

(c) a second replacement fluid conduit terminating in said first side of the expansion reservoir, the second replacement fluid conduit adapted for connection to a replacement fluid line conveying replacement fluid, the second replacement fluid conduit being effective to convey the replacement fluid to the expansion reservoir;

wherein

the first blood conduit terminates in the first access so that arterial blood which flows in the first blood conduit has a first flow direction having at least a first motion component directed towards the bottom of the expansion reservoir; and

the second conduit terminates in the first side of the expansion reservoir below the end of the first conduit, with reference to a use configuration of the expansion reservoir in which the bottom and the top are arranged, respectively, inferiorly and superiorly.

2. The chamber of claim 1, wherein the expansion reservoir has a second side opposite the first side and extending between the bottom and the top of the expansion reservoir, the first conduit terminating in the first access with the first flow direction having at least a second motion component directed towards said second side.

3. The chamber of claim 1, wherein the expansion reservoir has a second side opposite the first side and extending between the bottom and the top of the expansion reservoir, the second conduit terminating in the expansion reservoir with a second flow direction having at least a motion component directed towards said second side of the expansion reservoir.

4. The chamber of claim 1, wherein the second conduit terminates in the expansion reservoir with a second flow direction having at least a motion component directed towards the top of the expansion reservoir.

5. The chamber of claim 1, wherein:

the second conduit terminates in the expansion reservoir with a second flow direction having at least a first horizontal motion component, with reference to a use configuration of the expansion reservoir in which the bottom and the top are arranged, respectively, inferiorly and superiorly; and

the second conduit comprises an intermediate tract defining a flow direction including at least a second horizontal motion component going in a direction opposite the first horizontal motion component.

6. The chamber of claim 5, wherein the flow direction of the intermediate tract includes at least a vertical motion component.

7. The chamber of claim 1, wherein the first conduit has a diverging tract having a fluid passage section which broadens moving towards the first access.

8. The chamber of claim 7, wherein the diverging tract broadens moving towards the bottom of the expansion reservoir.

9. The chamber of claim 7, wherein:

the expansion reservoir has a substantially flat configuration with front and rear faces; and

the diverging tract broadens in a direction perpendicular to said front and rear faces.

10. The chamber of claim 7, wherein the diverging tract terminates at the first access.

11. The chamber of claim 1, wherein the first access is elongate and extends in a direction perpendicular to the first side.

12. The chamber of claim 1, wherein the second access is arranged at the bottom of the expansion reservoir.

13. The chamber of claim 1, wherein it comprises a third conduit terminating at the second access.

14. The chamber of claim 13, wherein the third conduit extends along a second side of the expansion reservoir located opposite the first side.

15. The chamber of claim 1, wherein the first conduit terminates in the first access with a first flow direction directed towards the second access.

16. The chamber of claim 1, wherein the first conduit extends along the first side.

17. The chamber of claim 1, wherein the second conduit terminates either in the first access, contiguously below the end of the first conduit, or in an intermediate access arranged between the first access and the bottom of the expansion reservoir.

18. The chamber of claim 1, wherein the expansion reservoir has an upper part, comprised between the first access and the reservoir top, having a greater width than a lower part comprised between the reservoir bottom and the first access.

19. The chamber of claim 1, wherein the first conduit meets the second conduit in a mixing zone, reaching said mixing zone at a position located above the second conduit, where above is intended with reference to a use configuration of the expansion reservoir in which the bottom and the top are arranged, respectively, inferiorly and superiorly.

20. The chamber of claim 19, wherein:

the first conduit is designed to introduce the flow into the mixing zone with at least a motion component directed downwards, with reference to the use configuration of the expansion reservoir; and

the second conduit is designed to introduce the flow into the mixing zone with at least a motion component directed from below in an upwards direction.

21. The chamber of claim 19, wherein the first conduit and the second conduit are designed so that each of the respective flows is introduced into the mixing zone with at least a horizontal motion component directed inwardly of the expansion reservoir.