Injection device

• US 8,647,306 B2
• Filed: 06/16/2009
• Issued: 02/11/2014
• Est. Priority Date: 06/16/2008
• Status: Active Grant

• Current Assignee: Pharma Consult Ges.m.b.H. & Co Nfg KG
• Original Assignee: Pharma Consult Ges.m.b.H. & Co Nfg KG
• Inventors: Schwirtz, Andreas, Csenar, Markus
• Primary Examiner(s): Bosworth, Kami A
• Application Number:
  US12/999,551
• Publication Number:
  US 20110125100A1
• Time in Patent Office: 1,701 Days
• Field of Search: 604/130, 604/131, 604134-137, 604/139, 604/156, 604/157, 604/187, 604/192, 604197-199, 604/110, 604/200, 604/201
• US Class Current: 604/192
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/2418 comprising means for damping shocks on ampoule
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

The invention relates to an injection device (1), which comprises a support housing (2), an activating sleeve (9), a cartridge (3) containing a medicine (14), a first drive unit (4), a safety device (5), a needle arrangement (6), a needle protection element (7) and a second triggerable drive unit (8), whereby the latter moves the needle protection element (7) from the non-effective position into the position covering one needle end (21) of a cannula (20). The support housing (2) is surrounded over most of its longitudinal extension between its distal and proximal end (11, 12) by the activating sleeve (9), whereby the needle protection element (7) with the second drive unit (8) cooperating therewith is arranged radially between the support housing (2) and the activating sleeve (9), as viewed in axial cross section.

Claims

1. An injection device configured to be adjustable from a storage position to an injection position, comprising:

a support housing having a distal end to be applied to a patient and a proximal end opposite the distal end, between which a longitudinal axis extends, the support housing further including;

a front support housing part including a casing, the front support housing part defining an opening at a distal end of the front support housing part and defining a front holding chamber, the casing extending from the opening to a connecting section, and

a rear support housing part defining a rear chamber, the front support housing part and the rear support housing part adapted to be coupled together in the connecting section via a coupling device in the direction of the longitudinal axis in two different longitudinal positions in a first and a second coupling position;

an activating sleeve at least partially surrounding the support housing and configured to be adjusted in an axial direction relative to the support housing, whereby the distal end of the support housing projects over the activating sleeve,

a cartridge adapted to retain medicine to be administered in an injection procedure is mounted in the support housing,

a first drive unit which is in active connection with the cartridge and the activating sleeve and can be triggered by means of the activating sleeve,

a safety device, which secures the first drive unit prior to its activation by the activating sleeve for the injection procedure in position relative to the support housing,

a needle arrangement, which is arranged ahead of the cartridge in the storage position of the injection device in the section of the distal end of the support housing, the needle arrangement comprising a cannula having distal and proximal needle ends arranged inside the support housing, the distal needle end being configured to pass through the opening defined by the front support housing part,

a needle protection element which can be displaced from a non-active position into a position which covers the distal needle end projecting over the distal end of the support housing after the injection procedure,

a second activatable drive unit, which displaces the needle protection element from the non-active position into the covering position,

a seal stopper disposed in the opening defined by the front support housing part,

a sealing element extending circumferentially between an external surface of the cartridge and an internal surface of the support housing in the connecting section,

at least one throughput disposed in the connecting section between the front support housing part and the rear support housing part such that, in the first coupling position, there is a flow connection via the throughput between the front holding chamber and an outside of the support housing, and, in the second coupling position, the flow connection is interrupted between the front holding chamber and the outside of the support housing,

wherein the needle protection element with the second drive unit cooperating therewith is arranged radially between the support housing and the activating sleeve.

2. The injection device according to claim 1, wherein the front support housing part grips over the rear support housing part in the connecting section of the coupling device.

3. The injection device according to claim 1, wherein the support housing parts in the first coupling position of the coupling device have a greater longitudinal extension relative to the second coupling position.

4. The injection device according to claim 1, wherein the coupling device on the two support housing parts comprises mutually cooperating locking elements configured such that the two support housing parts are locked respectively in the two coupling positions in an opposite direction of movement as viewed in the direction of the longitudinal axis and moving away from each other.

5. The injection device according to claim 1, wherein the front support housing part in the connecting section on a face side, which faces the rear support housing part and springs back in the direction of the longitudinal axis, comprises a shoulder which is wedge-shaped, as viewed in axial cross section, and designed to be continuous around the circumference of the front support housing part.

6. The injection device according to claim 1, wherein in the second coupling position of the two support housing parts the sealing element bears in a sealing manner against a back-springing face side or a shoulder arranged on the back-springing face side, and also access into the front holding chamber is interrupted by the throughput.

7. The injection device according to claim 1, wherein the rear support housing part on its external surface and in the region of its proximal end has at least two detent noses spaced apart in the direction of the longitudinal axis, which interact with a detent element arranged on the activating sleeve, such that the detent noses define relative positions of the support housing and the activating sleeve relative to one another on the one hand in the storage position and on the other hand in the injection position, and in that only a relative longitudinal displacement of the activating sleeve relative to the support housing is permitted from the storage position to the injection position, but a relative longitudinal displacement in the opposite direction is prevented.

8. The injection device according to claim 1, wherein the activating sleeve in the region of the distal end of the support housing and on its internal surface comprises a stop surface, which is aligned preferably at right angles to the longitudinal axis.

9. The injection device according to claim 1, wherein the needle protection element comprises a rocker-like lever element arranged with lever ends spaced apart from one another in the direction of the longitudinal axis, whereby the lever element in the storage position of the injection device has its distal-facing lever end supported on a stop element arranged on an external surface of the support housing.

10. The injection device according to claim 9, wherein the needle protection element comprises at its proximal end an elastically deformable safety element, which in the position of the needle protection element covering the needle arrangement is supported on a stop surface formed on an internal surface of the activating sleeve.

11. The injection device according to claim 1, further comprising a safety element adjacent to the needle protection element covering the needle arrangement and an adjusting element arranged on the support housing.

12. The injection device according to claim 11, wherein the adjusting element is designed to be continuous circumferentially and, in the position of the needle protection element covering the needle arrangement, the needle protection element is supported with its proximal end additionally on the adjusting element in the direction of the distal end of the support housing.

13. The injection device according to claim 1, wherein the needle arrangement comprises the cannula, a needle support arranged on the cannula and a guiding element mounting the needle support, whereby the guiding element is coupled with a cartridge end facing the distal end of the injection device and, in the storage position, the needle end of the cannula facing the cartridge end is arranged ahead of a cartridge seal which can be penetrated by the needle end.

14. The injection device according to claim 13, wherein the needle support is held axially displaceably in the guiding element and is secured in position on the guiding element in a storage position of the needle support by at least one releasable holding element relative to the guiding element.

15. The injection device according to claim 14, wherein an adjusting cam is arranged on the holding element, such that the cam projects over the holding element radially on a side opposite the longitudinal axis.

16. The injection device according to claim 1, wherein the first drive unit comprises a piston rod including a radially peripheral release designed as a depression, which is arranged in the storage position of the injection device in the region of a proximal end of the cartridge.

17. The injection device according to claim 1, wherein after releasing the safety device arranged at the proximal end and with a subsequent axial displacement of the activating sleeve relative to the support housing the first drive unit is triggered and the first drive unit displaces the cartridge together with the needle arrangement in the direction of the distal end of the support housing.

18. The injection device according to claim 1, wherein the support housing, at its distal end, comprises a control cam projecting in the direction of the longitudinal axis, which after a prespecifiable adjusting movement of the cartridge is in engagement with an adjusting cam arranged on a detachable holding element of a needle support, and thereby moves the detachable holding element into a release position.

19. The injection device according to claim 1, wherein a needle support is supported in the injection position on the distal end of the support housing and the needle support together with the cannula is displaced relative to a guiding element so far in the direction of a cartridge end closed by a penetrable cartridge seal, the proximal needle end of the cannula facing the cartridge is in flow connection with the medicine contained in the cartridge.

20. The injection device according to claim 1, wherein with the axial displacement of the activating sleeve relative to the support housing, the second drive unit cooperating with the needle protection element is released and thereby the needle protection element is shifted from a non-effective position into a position covering the distal needle end which projects over the distal end of the support housing after the injection procedure.

21. The injection device according to claim 1, wherein with the axial displacement of the activating sleeve relative to the support housing there is a simultaneous release of both the first and the second drive units.

22. The injection device according to claim 1, wherein the second drive unit comprises driving means supported with a distal-facing end section on a proximal facing end section of the needle protection element.

23. The injection device according to claim 1, wherein the safety device comprises a holding disc, which in the center of the holding disc comprises an opening as well as additionally adjoining radially outwards extending recesses for holding arms of the second drive unit to be secured to the holding disc in the storage position.

24. The injection device according to claim 1, further comprising a bacteria-tight casing for use during sterilization, the bacteria-tight casing surrounding other elements of the device and being gas-permeable for gassing with ethylene oxide.

25. The injection device according to claim 24, wherein prior to performing the sterilization thereof, the bacteria-tight casing is placed in a bath-like holding shell and in a region of a container edge the holding shell is sealed by means of a bacteria-tight cover which is still gas-permeable for gassing with ethylene oxide.

26. The injection device according to claim 24, wherein the bacteria-tight casing comprising a paper-fleece-like fiber functional textile made from thermally fused fibers of high density polyethylene (HDPE).