Devices and methods for treatment of vascular aneurysms

• US 8,647,377 B2
• Filed: 10/29/2012
• Issued: 02/11/2014
• Est. Priority Date: 11/26/2001
• Status: Active Grant

• Current Assignee: Endologix
• Original Assignee: Thomas J. Fogarty
• Inventors: Kim, Steven W., Shiu, Brian K.
• Primary Examiner(s): SEVERSON, RYAN J
• Application Number:
  US13/663,272
• Publication Number:
  US 20130261724A1
• Time in Patent Office: 470 Days
• Field of Search: 606/200, 623/1.15, 623/1.25, 623/1.36
• US Class Current: 623/1.11
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/00986 Malecots, e.g. slotted tubes, of which the distal end is pulled to deflect side struts
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/3484 Anchoring means, e.g. spreading-out umbrella-like structure
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/077 having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas

Abstract

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Claims

1. A method for filling an aneurysm sac comprising,

placing a catheter configured to deliver a space-occupying device across an aneurysm cavity,

placing an expandable structure across the aneurysm cavity, wherein the space-occupying device is radially outside the expandable structure during the placing of the expandable structure, and

filling the aneurysm sac with the space-occupying device;

wherein the device comprises a first stent at the terminal end of the first longitudinal end and a second stent at the terminal end of the second longitudinal end, and wherein the first stent is the adjacent structural reinforcement element to the second stent;

wherein the space-occupying device and the catheter are substantially co-axial after the filling the aneurysm sac, and wherein the space-occupying device comprises a solid and/or solidifiable medium.

2. The method of claim 1, wherein filling comprises placing the catheter into the aneurysm sac.

3. The method of claim 1, wherein filling further comprises inflating a balloon on the catheter after the catheter is placed across the aneurysm cavity.

4. The method of claim 3, wherein delivering the space-occupying device comprises pushing the space-occupying device along the catheter with a plunger.

5. The method of claim 1, wherein the space-occupying device comprises a sponge.

6. The method of claim 5, wherein filling comprises placing the catheter into the aneurysm sac.

7. The method of claim 1, wherein filling further comprises inflating a balloon on the catheter after the catheter is placed across the aneurysm cavity.

8. The method of claim 1, wherein delivering the device comprises pushing the device along the catheter with a plunger.

9. The method of claim 1, wherein the expandable structure comprises the space-occupying device.

10. The method of claim 1, wherein the space-occupying device comprises the balloon.

11. The method of claim 1, wherein the space-occupying device substantially seals the aneurysm sac.

12. A method for filling an aneurysm cavity with a graft comprising an implant balloon and a longitudinal axis along a longer axis of the graft in a pre-deployment configuration, the method comprising,

positioning the graft at the aneurysm, wherein the graft is loaded radially outside a catheter, and wherein a first end of the graft is longitudinally concurrent with the catheter and wherein a second end of the graft is longitudinally concurrent with the catheter, and wherein a first stent is located at the first end of the graft, and wherein a second stent is located at the second end of the graft, and wherein the first stent is the adjacent structural reinforcement element to the second stent on the graft;

inflating the implant balloon, wherein inflating comprises inflating with a filling medium comprising a solid and/or solidifiable medium, and

detaching and removing the catheter from the graft.

13. The method of claim 12, wherein the inflating medium comprises an epoxy.

14. The method of claim 12, wherein the inflating comprises silicone.

15. The method of claim 12, wherein the inflating comprises urethane.

16. The method of claim 12, wherein the inflating comprises albumin.

17. The method of claim 12, wherein the inflating comprises collagen.

18. The method of claim 12, wherein the inflating comprises gelatin glue.

19. The method of claim 12, wherein the inflating comprises saline.

20. The method of claim 12, wherein the inflating comprises a contrast agent.

21. The method of claim 12, wherein the inflating comprises a biocompatible oil.

22. The method of claim 12, wherein the inflating comprises a biocompatible adhesive.

23. The method of claim 12, wherein the inflating comprises a UV-curable adhesive.

24. A method for filling an aneurysm sac in a subject comprising,

placing a catheter across an aneurysm cavity,

placing an expandable structure across the aneurysm cavity, and

filling the aneurysm sac with a space-occupying device comprising a solid and/or solidifiable medium;

wherein the space-occupying device is outside the catheter and inside the subject before the filling of the aneurysm sac and after placing the expandable structure; and

wherein a first stent is located at a first terminal end of the space-occupying device, and wherein a second stent is located at a second terminal end of the space-occupying device, and wherein the first stent is the adjacent structural reinforcement element to the second stent on the space-occupying device.

25. A method for filling an aneurysm sac comprising,

placing a catheter across an aneurysm cavity,

placing an expandable structure across the aneurysm cavity, wherein a space-occupying device is radially outside and substantially encircles the catheter during the placing the expandable structure;

and wherein a first stent is located at a first end of the expandable structure, and wherein a second stent is located at a second end of the expandable structure, and wherein the first stent is the adjacent structural reinforcement element to the second stent on the expandable structure, and

filling the aneurysm sac with the space-occupying device, wherein the space-occupying device comprises a solid and/or solidifiable medium.

26. A method for filling an aneurysm cavity with a graft comprising an implant balloon, a longitudinal axis along a longer axis of the graft in a pre-deployment configuration, a first stent at a first longitudinal end of the graft, a second stent at a second longitudinal end of the stent, and wherein the first stent is the longitudinally adjacent structural reinforcement element to the second stent on the graft, the method comprising:

positioning the graft at the aneurysm, wherein the graft is loaded radially outside and substantially longitudinally concurrent with a catheter,

inflating the implant balloon, wherein inflating comprises inflating with a filling medium comprising a solid and/or solidifiable medium, and

detaching and removing the catheter from the graft.