Photomodulation methods and devices for regulating cell proliferation and gene expression
First Claim
1. A method of dermatological treatment comprising exposing human tissue to electromagnetic radiation having an energy fluence to modulate cell activity of the genotype that when expressed produces a phenotype of aging skin, wherein the bandwidth of the electromagnetic radiation is greater than +/−
- about 10 nm about a dominant emissive wavelength, and wherein the energy fluence of the electromagnetic radiation inhibits the production of a gene expression pattern that produces aging-related indications changes and/or stimulates the production and activity of a gene expression pattern that retards aging or produces youthful characteristics.
6 Assignments
0 Petitions
Accused Products
Abstract
Human and mammalian skin undergoes a variety of changes associated with chronological aging. Various environmental factors, disease states and genetic disorders may accelerate both the appearance of aging skin and also the structural and functional changes associated with aging skin. Ultraviolet radiation from the sun is one of the classic known and well-defined means of accelerating or worsening the aging of the skin and this is frequently termed photoaging. Other environmental factors, such as oxidative stress, free radicals, environmental toxins such as ozone and cultural customs or habits such as tobacco smoking are other known probe accelerators in photo aging skin. A wide variety of other factors known and unknown contribute to accelerated or premature aging of the skin. This invention discusses methods where electromagnetic radiation, in particular, light, can be used to photobiomodulate the activity of living cells to delay, diminish, retard or even reverse the structural and functional effects of aging of the skin and other living cells and tissues. In particular methods described for improving the appearance, structure, function of aging skin, including up and down regulating the genotypic markers for the phenotype of aging skin.
338 Citations
7 Claims
-
1. A method of dermatological treatment comprising exposing human tissue to electromagnetic radiation having an energy fluence to modulate cell activity of the genotype that when expressed produces a phenotype of aging skin, wherein the bandwidth of the electromagnetic radiation is greater than +/−
- about 10 nm about a dominant emissive wavelength, and wherein the energy fluence of the electromagnetic radiation inhibits the production of a gene expression pattern that produces aging-related indications changes and/or stimulates the production and activity of a gene expression pattern that retards aging or produces youthful characteristics.
- View Dependent Claims (2, 3, 4, 5, 6, 7)
Specification